Hypothalamic Median Eminence Thyrotropin-Releasing Hormone-Degrading Ectoenzyme Activity Is Dispensable for Basal Thyroid Axis Activity in Lean Rodents [PDF]
The amplitude of the phasic output of thyrotropin-releasing hormone (TRH) into the hypothalamus–pituitary portal capillaries is likely controlled by the TRH-degrading ectoenzyme (TRH-DE) expressed on the surface of median eminence (ME) β2-tanycytes.
Adair Rodríguez-Rodríguez +4 more
doaj +2 more sources
Role of the thyrotropin-releasing hormone of the limbic system in mood and eating regulation
Thyrotropin-releasing hormone (TRH) and its receptors are expressed in the hypothalamus and limbic regions. Brain thyrotropin-releasing hormone actions are exerted directly through its receptors and indirectly by modulating the effects of ...
Elena Alvarez-Salas +3 more
doaj +1 more source
Biochemical and physiological insights into TRH receptor-mediated signaling
Thyrotropin-releasing hormone (TRH) is an important endocrine agent that regulates the function of cells in the anterior pituitary and the central and peripheral nervous systems.
Radka Trubacova +2 more
doaj +1 more source
Visual Reinforcement Audiometry (VRA): examination method of hearing in the youngest children
What does a child actually hear? At what intensities and at what frequencies? The answers to these questions are extremely difficult, because a child is not able to describe his/her auditory perception to us, as an adult would.
Petra Šestáková, Radan Havlík
doaj +1 more source
NR4A1 (Nur77) mediates thyrotropin-releasing hormone-induced stimulation of transcription of the thyrotropin β gene: analysis of TRH knockout mice. [PDF]
Thyrotropin-releasing hormone (TRH) is a major stimulator of thyrotropin-stimulating hormone (TSH) synthesis in the anterior pituitary, though precisely how TRH stimulates the TSHβ gene remains unclear. Analysis of TRH-deficient mice differing in thyroid
Yasuyo Nakajima +11 more
doaj +1 more source
Cardiac Arrest Developing Linked to Hydatid Cyst Rupture During Operation of a Pediatric Patient
Hydatid cysts are parasitic infections created by echinococcus granulosus and echinococcus alveolaris. These infections are characterized by cyst formation with cysts most commonly localized in the liver and lungs. With rupture of the cyst due to trauma,
Bedih Balkan +6 more
doaj +1 more source
The Thyrotropin-Releasing Hormone-Degrading Ectoenzyme, a Therapeutic Target?
Thyrotropin releasing hormone (TRH: Glp-His-Pro-NH2) is a peptide mainly produced by brain neurons. In mammals, hypophysiotropic TRH neurons of the paraventricular nucleus of the hypothalamus integrate metabolic information and drive the secretion of ...
Jean-Louis Charli +6 more
doaj +1 more source
Growth Hormone (GH)-Releasing Peptide Stimulation of GH Release from Human Somatotroph Adenoma Cells: Interaction with GH-Releasing Hormone, Thyrotropin- Releasing Hormone, and Octreotide. [PDF]
The synthetic hexapeptide GH-releasing peptide (GHRP; His-D-Trp-Ala-Trp-D-Phe-Lys-NH2) specifically stimulates GH secretion in humans in vivo and in animals in vitro and in vivo via a still unknown receptor and mechanism.
Brockmeier, S. +7 more
core +1 more source
The decrease in growth hormone (GH) response after repeated stimulation with GH-Releasing hormone is partly caused by an elevation of somatostatin tonus. [PDF]
Repeated injection of GHRH leads to a decrease in the GH response in normal subjects. Arginine (Arg) stimulates GH secretion by suppression of hypothalamic somatostatin.
Mehltretter, Gerhard +5 more
core +1 more source
Vibrio parahaemolyticus is a major foodborne pathogen responsible for significant economic losses in aquaculture and a threat to human health. Here, we explored the incidence, virulence potential, and diversity of V.
Abu Baker Siddique +10 more
doaj +1 more source

