Results 121 to 130 of about 46,961 (245)

Divergent Access to Fluorinated Pharmacons From Ethyl Trifluoropyruvate

open access: yesAdvanced Synthesis &Catalysis, Volume 368, Issue 7, 1 April 2026.
Fluoro(oxo) functional group diversification is traditionally accomplished through either specialized reagents or nucleophilic trifluoromethylation. Herein is disclosed the use of commercially available building blocks for the synthesis of trifluoromethyl(hydroxy) esters.
Rifat N. Nabi   +4 more
wiley   +1 more source

From Covalent Traps to Fluorescent Beacons: The Expanding Arsenal of Chemical Probes for Studying Ubiquitin and Ubiquitin‐Like Proteins

open access: yesAngewandte Chemie, Volume 138, Issue 13, 23 March 2026.
A large variety of chemistry‐based ubiquitin probes have been developed. ABSTRACT Ubiquitin (Ub) and ubiquitin‐like proteins (Ubls) orchestrate diverse cellular processes through reversible post‐translational modification of target proteins. Their conjugation is governed by a cascade of E1 activating, E2 conjugating, and E3 ligating enzymes, while ...
Saibal Chanda, Wenshe Ray Liu
wiley   +2 more sources

Characteristics of fungicide resistance in Asian soybean rust (Phakopsora pachyrhizi) in Paraguay for 2022–2023: insights from genetic mutations and molecular dynamics simulations

open access: yesPest Management Science, Volume 82, Issue 4, Page 3116-3126, April 2026.
Phakopsora pachyrhizi in Paraguay showed diverse resistance to DMI, SDHI, and QoI fungicides at both regional and intra‐field levels, likely driven by target mutation genes. Abstract BACKGROUND Phakopsora pachyrhizi, the causative agent of Asian soybean rust, poses a major threat to soybean production in South America. The rising incidence of fungicide
Ryusuke Hagihara   +5 more
wiley   +1 more source

A new method to measure EC50 reveals cultivar‐specific fungicide resistance and very high diversity within experimental field populations of Zymoseptoria tritici

open access: yesPest Management Science, Volume 82, Issue 4, Page 3613-3624, April 2026.
We isolated Zymoseptoria tritici strains from a diverse wheat field and quantified fungicide resistance using a novel plate assay. We found high diversity in fungicide sensitivity and host–fungicide–pathogen interactions. Abstract BACKGROUND Zymoseptoria tritici causes Septoria tritici blotch (STB), the most damaging wheat disease in Europe. In Europe,
Firas Talas   +2 more
wiley   +1 more source

Sensitivity to demethylation‐inhibiting fungicides and induced expression of CYP51 associated with tebuconazole resistance in Alternaria species on mandarin in Brazil

open access: yesPest Management Science, Volume 82, Issue 4, Page 3663-3676, April 2026.
Tebuconazole‐resistant isolates overexpress CYP51 and, when tested at field rates, did not reduce ABS severity, whereas difenoconazole and mefentrifluconazole remained effective. Abstract BACKGROUND Alternaria brown spot (ABS), caused by Alternaria spp., is an important disease affecting mandarin production in several citrus‐growing regions worldwide ...
Thiago de Aguiar Carraro   +7 more
wiley   +1 more source

Modification of the existing maximum residue levels for prothioconazole in various crops. [PDF]

open access: yesEFSA J
European Food Safety Authority (EFSA)   +18 more
europepmc   +1 more source

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