Results 11 to 20 of about 178,442 (380)
Triazole analogues as potential pharmacological agents: a brief review
Future Journal of Pharmaceutical Sciences, 2021 Background A large number of studies have recently reported that, because of their significant biological and pharmacological properties, heterocyclic compounds and their derivatives have attracted a strong interest in medicinal chemistry.
Sachin Kumar +2 more
doaj +2 more sources
Mutations in
mBio, 2019 Aspergillus fumigatus is the predominant pathogen of invasive aspergillosis, a disease state credited with over 200,000 life-threatening infections each year.
Jeffrey M. Rybak +6 more
doaj +2 more sources
LXII.—C-Phenyl-s-triazole [PDF]
J. Chem. Soc., Trans., 1905 n ...
George W. Young
openalex +4 more sources
1,2,4-Triazoles. VII. Methylation of 1,2,4-triazoles.
Chemical and Pharmaceutical Bulletin, 1976 AbstractMethylierung von 1,2,4‐Triazol und dessen symmetrisch 3,5‐disubst.
Masayuki Uda +3 more
openalex +5 more sources
Synthesis methods of 1,2,3-/1,2,4-triazoles: A review
Frontiers in Chemistry, 2022 Triazole, comprising three nitrogen atoms and two carbon atoms, is divided into two isomers 1,2,3-triazole and 1,2,4-triazole. Compounds containing a triazole are one of the significant heterocycles that exhibit broad biological activities, such as ...
Jinlian Dai +3 more
doaj +1 more source
Pharmacotherapy, 2023 Triazole antifungals (i.e., fluconazole, itraconazole, voriconazole, posaconazole, and isavuconazole) are commonly used in clinical practice to prevent or treat invasive fungal infections.
E. McCreary +9 more
semanticscholar +1 more source
An Overview of 1,2,3-triazole-Containing Hybrids and Their Potential Anticholinesterase Activities
Pharmaceuticals, 2023 Acetylcholine (ACh) neurotransmitter of the cholinergic system in the brain is involved in learning, memory, stress responses, and cognitive functioning.
S. Khan +4 more
semanticscholar +1 more source
Fluorescent Analogues of FRH Peptide: Cu(II) Binding and Interactions with ds-DNA/RNA
Chemosensors, 2022 Four novel peptidoids, derived from the Phe-Arg-His (FRH) peptide motif, were prepared by replacing the histidine heterocycle with triazole and consequent triazole-fluorophore (coumarin) extension and also replacing arginine with less voluminous lysine ...
Marta Košćak +3 more
doaj +1 more source
Benzimidazole-Triazole Hybrids as Antimicrobial and Antiviral Agents: A Systematic Review
Antibiotics, 2023 Bacterial infections have attracted the attention of researchers in recent decades, especially due to the special problems they have faced, such as their increasing diversity and resistance to antibiotic treatment.
M. Marinescu
semanticscholar +1 more source
Enantiomer stability of atropisomeric 1,5-disubstituted 1,2,3-triazoles
Tetrahedron Chem, 2022 The synthesis and characterisation of axially chiral atropisomeric 1,5-disubstituted 1,2,3-triazoles is reported. Molecules designed to display restricted rotation about 1,2,3-triazole N-1-aryl or 1,2,3-triazole C-5-aryl bonds were investigated by ...
Fernanda Meloni +6 more
doaj +1 more source