Results 41 to 50 of about 178,442 (380)

Multiple-Triazole–Resistant Aspergillosis [PDF]

New England Journal of Medicine, 2007
To the Editor: The use of voriconazole has become common for the management of invasive aspergillosis. However, therapy with voriconazole still sometimes fails, more often because of unresponsive underlying disease than because of resistance of the fungus.
Verweij, P.E., Mellado, E., Melchers, W.J.G.   +2 more
openaire   +5 more sources

Decarboxylative Triazolation Enables Direct Construction of Triazoles from Carboxylic Acids

JACS Au, 2023
Triazoles have major roles in chemistry, medicine, and materials science, as centrally important heterocyclic motifs and bioisosteric replacements for amides, carboxylic acids, and other carbonyl groups, as well as some of the most widely used linkers in click chemistry.
Hang T. Dang, Viet D. Nguyen, Graham C. Haug, Hadi D. Arman, Oleg V. Larionov   +4 more
openaire   +2 more sources

Diuretic activity of 3-(5-bromfuran-2-yl)-4-r-(4h)-1,2,4-triazole-5-thione, their S-derivatives and 2-(5-bromfuran-2-yl)-5-r'-thiazolo[3,2-b][1,2,4]triazole-6(5h)-ones

Aktualʹnì Pitannâ Farmacevtičnoï ì Medičnoï Nauki ta Praktiki, 2015
The aim of study was to investigate diuretic activity of 1,2,4-triazole derivatives which contain С5 atom 5-bromfuran-2-yl substituent in the 1,2,4-triazole nucleus, and to establish interrelation between chemical structure and diuretic action of 1,2,4 ...
Ye. S. Pruglo, A. S. Gotsulya, O. I. Panasenko, Ye. G. Knysh   +3 more
doaj   +1 more source

Antimicrobial and antifungal activity of new 4-(5-((5-(alkylthio)-4-R-4H-1,2,4-triazole-3-yl)thio)-1H-1,2,4-triazole-3-yl)pyridines

Aktualʹnì Pitannâ Farmacevtičnoï ì Medičnoï Nauki ta Praktiki, 2020
The resistance of such strains as Staphylococcus aureus, Escherichia coli extends to many antimicrobial drugs. This problem can be solved by searching for new drugs with high bactericidal and antifungal action.
Ye. O. Karpun, N. M. Polishchuk
doaj   +1 more source

Synthesis of a ditopic homooxacalix[3]arene for fluorescence enhanced detection of heavy and transition metal ions [PDF]

, 2015
A pyrene-appended ratiometric fluorescent chemosensor L based on a synthetic approach of insulating the fluorophore from the ionophore by a specific molecular spacer has been synthesised and characterised.
Jin, Cheng-Cheng, Mou, Lan, Ni, Xin-Long, Redshaw, Carl, Wu, Yanan, Yamato, Takehiko   +5 more
core   +2 more sources

An Overview on the Performance of 1,2,3-Triazole Derivatives as Corrosion Inhibitors for Metal Surfaces

International Journal of Molecular Sciences, 2021
This review accounts for the most recent and significant research results from the literature on the design and synthesis of 1,2,3-triazole compounds and their usefulness as molecular well-defined corrosion inhibitors for steels, copper, iron, aluminum ...
Meryem Hrimla, Lahoucine Bahsis, M. R. Laamari, M. Julve, Salah‐E. Stiriba   +4 more
semanticscholar   +1 more source

Safety of triazole antifungals: a pharmacovigilance study from 2004 to 2021 based on FAERS

Therapeutic Advances in Drug Safety, 2022
Background: Triazole antifungals are widely used as broad-spectrum antifungal activity; however, there are many undetected and unreported adverse events (AEs).
Shuang Chai, Jing-Lun Zhan, Li-Mei Zhao, Xiao-Dong Liu   +3 more
doaj   +1 more source

Preparation and antitumor effects of 4-amino-1,2,4-triazole Schiff base derivative

Journal of International Medical Research, 2020
Objectives The purpose of this paper was to synthesize 4-amino-1,2,4-triazole Schiff base derivative and to evaluate its antitumor activity. Methods 2,4,6-Tris (4-formylphenoxy)-1,3,5-triazine was synthesized by nucleophilic substitution with reaction of
Guo-wei Jiang, Qing Chang, Dong-yu Liang, Yu-ting Zhang, Yong-jun Meng, Qing-qing Yi   +5 more
doaj   +1 more source

Coordinatively unsaturated ruthenium complexes as efficient alkyne-azide cycloaddition catalysts [PDF]

, 2012
The performance of 16-electron ruthenium complexes with the general formula Cp*Ru(L)X (in which L = phosphine or N-heterocyclic carbene ligand; X = Cl or OCH2CF3) was explored in azide−alkyne cycloaddition reactions that afford the 1,2,3- triazole ...
Broggi, Julie, Cavallo, Luigi, Fortman, George C., Lamberti, Marina, Nolan, Steven P., Poater, Albert, Slawin, Alexandra M. Z.   +6 more
core   +2 more sources

Isolation of bis(copper) key intermediates in Cu-catalyzed azide-alkyne "click reaction". [PDF]

, 2015
The copper-catalyzed 1,3-dipolar cycloaddition of an azide to a terminal alkyne (CuAAC) is one of the most popular chemical transformations, with applications ranging from material to life sciences.
Bertrand, Guy, Jin, Liqun, Melaimi, Mohand, Tolentino, Daniel R   +3 more
core   +2 more sources