Results 131 to 140 of about 49,489 (310)
Journal of Enzyme Inhibition and Medicinal Chemistry, 2017 A new series of novel 7-hydroxy-4-phenylchromen-2-one (1a)–linked 1,2,4-triazoles were synthesised using a click chemistry approach. All derivatives were subjected to 3-(4,5-dimethylthiazol-yl)-diphenyl tetrazolium bromide (MTT) cytotoxicity screening ...
Chuan-Feng Liu +4 more
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Next-generation text-mining mediated generation of chemical response-specific gene sets for interpretation of gene expression data [PDF]
, 2013 Background: Availability of chemical response-specific lists of genes (gene sets) for pharmacological and/or toxic effect prediction for compounds is limited. We hypothesize that more gene sets can be created by next-generation text mining (next-gen TM),
Boorsma, J. (Jeffrey) +8 more
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Phosphinoisocyanide Cyclisation: Generation of Azaphospholylidene (NPHC) Ligands
Angewandte Chemie International Edition, Accepted Article.Phosphinoisocyanide complexes undergo facile [3+2] cycloaddition reactions with activated alkynes to afford the first azaphospholylidene complexes which are rare examples of N,P‐heterocyclic carbenes (NPHC). In addition to quantifying the donor/acceptor properties of this new class of carbene, their transmetallation reactions are also described.
Anthony Francis Hill, Ryan M. Kirk
wiley +1 more source
Drug, Healthcare and Patient Safety, 2010 Dionissios Neofytos1, Edina Avdic2, Anna-Pelagia Magiorakos31Transplant and Oncology Infectious Disease Program, The Johns Hopkins University School of Medicine, Division of Infectious Diseases, 2Department of Pharmacy, The Johns Hopkins Hospital ...
Dionissios Neofytos +2 more
doaj
The Preparation of Some N-Methyl-1,2,3-Triazoles. [PDF]
, 1959 Christian Pedersen +5 more
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Ruthenium Catalyzed ortho‐Arylation Reaction of Benzoic Acids with Arylthianthrenium Salts
Angewandte Chemie International Edition, Accepted Article.Arylthianthrenium salts have become key intermediates for late‐stage functionalizations of drug‐like molecules. Ruthenium‐phosphine catalysts are now shown to enable their use as aryl sources in high‐yielding ortho‐C–H arylations of benzoic acids. The arylthianthrenium salts are converted chemo‐selectively, leaving aryl halides and boronates untouched.
Kaiping Wang +9 more
wiley +1 more source
Triazole aus Dibenzamid, beziehungsweise Diparatoluylamid und Hydrazinsalzen [PDF]
, 1916 Herbert Wolchowe
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1, 2, 3 - Triazoles as key frameworks in drug discovery & metal catalysis [PDF]
, 2017 356 p.La tesis se enmarca dentro de la química de los 1H-1,2,3-triazoles y sus sales de N-alquil-triazolio. El trabajo realizado contempla los siguientes objetivos:1.- Sintetizar y estudiar los 1H-1,2,3-triazoles como plantillas moleculares de fármacos ...
Irastorza Epelde, Aitziber
core
Studies on Oxidation. Part IV. Action of Ferric Chloride and Hydrogen Peroxide on S-Alkyl thiosemicarbazones: Formation ol Triazoles. [PDF]
, 1930 SATISH CHANDRA DE +1 more
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Reactivity of Pnictaalumenes towards 1,3‐Dipole Molecules
Angewandte Chemie International Edition, Accepted Article.Alkynes undergo 1,3‐dipolar cyclisation reactions with organic azides giving 1,2,3‐triazoles. Pnictaalumenes RPn=AlRˈ are the isoelectronic congeners of alkynes, hence a similar reactivity towards 1,3‐dipole molecules is expected. Herein, we report the reactions of DippTerPn=AlCp* (DippTer = 2,6‑(2,6‐iPr2C6H3)‐C6H3, Cp* = [Me5C5]−, Pn = P, As) towards ...
Tim Wellnitz +7 more
wiley +1 more source