Results 121 to 130 of about 37,042 (298)
Selective C(sp2)–H Halogenation of “Click” 4‑Aryl-1,2,3-triazoles
, 2017 Selective bromination reactions of “click compounds” are described. Electron-neutral and electron-deficient arenes selectively undergo unprecedented Pd-catalyzed C–H ortho-halogenations assisted by simple triazoles as modular directing groups, whereas ...
Asier Goitia (3728104) +2 more
core +1 more source
Angewandte Chemie, EarlyView.Pt1, an organometallic platinum‐based complex, act as a modulator of redox homeostasis in cnidarians, regulating cellular functions and life‐cycle dynamics. In Nematostella vectensis, it mitigates oxidative stress, strengthens detox systems and accelerates development.
Giuseppina Tommasini +13 more
wiley +2 more sources
Progress and Prospects of Triazoles in Advanced Therapies for Parasitic Diseases
Tropical Medicine and Infectious DiseaseParasitic diseases represent a severe global burden, with current treatments often limited by toxicity, drug resistance, and suboptimal efficacy in chronic infections.
Jaime A. Isern +3 more
doaj +1 more source
An aqueous medium synthesis and tautomerism study of 3(5)-amino-1,2,4-triazoles
, 2009 A catalyst-free highly efficient synthesis of 3(5)-amino-5(3)-(het)aryl-1,2,4-triazoles in aqueous mediumwas performed using conventional heating and microwave irradiation.
W. Chui (23304466) +3 more
core
Supramolecular Polymer‐Surfactant Co‐Assemblies for Multivalent HSV‐1 Inhibition
Angewandte Chemie, EarlyView.Non‐covalent co‐assembly of BTA with antiviral surfactants produces ratio‐dependent morphologies. Fibrous supramolecular polymers exhibit superior HSV‐1 inhibition, revealing multivalent fiber‐virus interactions and highlighting supramolecular co‐assemblies as a powerful strategy for functional biomedical nanomaterials with demonstrated tunable ...
Christian Zoister +12 more
wiley +2 more sources
Anticancer properties of 1,2,4-triazole derivatives (literature review)
Aktualʹnì Pitannâ Farmacevtičnoï ì Medičnoï Nauki ta PraktikiCancer is still one of the leading causes of death worldwide. Statistical data show that more than 130,000 people in Ukraine receive this diagnosis as a sentence every year. Cancer can affect any organ and eventually the whole body. In most cases, cancer
I. V. Bushuieva, M. V. Parchenko
doaj +1 more source
1,2,3-Triazole N(2)-chelated C–S coupling: Access to ortho methylthiolated 1,2,3-triazoles
, 2019 CuF2-mediated selective C-S coupling of 1,4-disubstituted 1,2,3-triazole halides using the widely available DMSO as the methylthiolation reagent were achieved through the chelation of N(2) atom in triazole ring. The ortho- C-halogen bond in N(1) aryl was
Yubo Jiang (4426555) +5 more
core +1 more source
Nature CommunicationsChiral 1,2,3-triazoles are highly attractive motifs in various fields. However, achieving catalytic asymmetric click reactions of azides and alkynes for chiral triazole synthesis remains a significant challenge, mainly due to the limited catalytic ...
Ling-Feng Jiang +9 more
doaj +1 more source
The Click Reaction as an Efficient Tool for the Construction of Macrocyclic Structures
Molecules, 2013 The Cu(I)-catalyzed azide-alkyne cycloaddition (CuAAC, known as the click reaction) is an established tool used for the construction of complex molecular architectures.
Dario Pasini
doaj +1 more source
Drug, Healthcare and Patient Safety, 2010 Dionissios Neofytos1, Edina Avdic2, Anna-Pelagia Magiorakos31Transplant and Oncology Infectious Disease Program, The Johns Hopkins University School of Medicine, Division of Infectious Diseases, 2Department of Pharmacy, The Johns Hopkins Hospital ...
Dionissios Neofytos +2 more
doaj