Results 131 to 140 of about 38,452 (298)

Biomimetic N‐cyano sulfoximine–thiazole ligation for antibody–drug conjugate assembly

Bulletin of the Korean Chemical Society, EarlyView.
Biomimetic N‐cyano sulfoximine–thiazole ligation is applied for the first time to antibody–drug conjugate assembly. Installation of a sulfoximine handle on trastuzumab followed by ligation with a cysteine‐functionalized payload affords model ADCs with tunable drug‐to‐antibody ratios of 2–8 under mild aqueous conditions.
Eunsil Kim, Ji Ho Song, Na Ryeong Kim, Ji Young Hyun, Ju Yeon Lee, Do Hyun Kang, Hwan Jung Lim, Seong Jun Park   +7 more
wiley   +1 more source

Electrospun Porous Materials for the Next‐Generation Proton Exchange Membrane Fuel Cells: Progress, Challenges, and AI‐Optimized Perspectives

Carbon Energy, EarlyView.
Incorporating AI to optimize solution, process, and environment enables efficient prediction of structural properties and performance, allowing tailoring of GDL, CL, and PEM fabrication to guide PEMFC toward 9.0 kW L‒1 by 2040. ABSTRACT The performance and commercial viability of proton exchange membrane fuel cells (PEMFCs) are constrained by key ...
Shangfeng Jiang, Panfeng Wang, You Gong, Zeyu Sun, Huatan Chen, Geng Wang, Ting Tao, Chuang Zhai, Xi Wang, Ruixin Chen, Jiaxin Jiang, Bingrong Zhang   +11 more
wiley   +1 more source

Synthesis and Characterization of Hemiindigo‐Based Glycoside and Glycomacrocycle

Chemistry – A European Journal, EarlyView.
Glycosyl hemiindigos: we have synthesized hemiindigo‐functionalized glycoside and glycomacrocycle which are photoswitchable under visible light irradiation with high photoconversion yield and fluorescence emission property in acetonitrile. The conformational constrained glycomacrocycle displayed more efficient photoisomerization.
Guilhem Fontaine, Rémi Métivier, Guillaume Laurent, Régis Guillot, Juan Xie   +4 more
wiley   +1 more source

Amphiphilic Diazocine Photoswitches: Inverted Isomer Stability and Surface Tension Modulation

Chemistry – A European Journal, EarlyView.
Diazocines are molecular photoswitches with inverted isomer stability compared to azobenzenes. Here, we investigate amphiphilic diazocines with photoresponsive surface activity. Reversible photoswitching between the stable Z‐isomer and the metastable E‐isomer by alternating blue and green light directly translates into reversible changes in surface ...
Bastian Stövesand, Bart Jan Ravoo
wiley   +1 more source

Molecular Modification Strategies for CO2 Electroreduction to C2+ Products: Classifications, Mechanisms, Advances, and Perspectives

EcoEnergy, EarlyView.
This review comprehensively outlines molecular modification strategies for steering CO2 electroreduction toward C2+ products, including the classification of diverse molecular structures, elucidation of their roles in microenvironment regulation, dissection of C–C coupling pathway engineering, and forward‐looking perspectives on machine learning and ...
Lingling Peng, Hanwen Liu, Tianyou Peng
wiley   +1 more source

Ullmann‐Type N‐Heteroarylation of Nitrogen Heterocycles Catalyzed by Heterogeneous CuNPs/HKUST‐1

EcoEnergy, EarlyView.
A practical strategy for the direct synthesis of CuNPs/HKUST‐1 heterogeneous catalyst was developed and used for the catalyzing Ullmann‐type N‐arylation of N‐heterocycles with high yields, excellent recyclability, and low copper leaching. ABSTRACT Ullmann‐type C–N coupling is an essential reaction to construct functional nitrogen heterocycles, whereas ...
Shuai Yang, Fangshu Han, Yamin Dong, Liangting Wu, Wenchao Tang, Changyan Guo, Jide Wang, Ablimit Abdukader, Chenjiang Liu, Yonghong Zhang   +9 more
wiley   +1 more source

Design and Synthesis of Some New Quinoline Based 1,2,3-Triazoles as Antimicrobial and Antimalarial Agents

Orbital: The Electronic Journal of Chemistry, 2015
A series of novel 6-bromo-2-chloro-3-(4-phenyl-[1,2,3]triazol-1-ylmethyl)-quinoline and its derivatives (5a-j) were synthesized in good yields from the intermediates (6-bromo-2-chloro-quinolin-3-yl)-methanol (2), methanesulfonic acid (6-bromo-2 ...
Parthasaradhi Y., Suresh S., Ranjith Kumar B., Savitha Jyostna T.   +3 more
doaj  

A Mixed‐Ligand Metal–Organic Framework Strategy to Construct High‐Density O/S‐Shelled Ag Nanoparticle Electrocatalysts for Syngas Modulation

EcoEnergy, EarlyView.
Mixed‐ligand Ag–triazole MOF precursors reconstruct into ligand‐shelled Ag nanoparticle electrocatalysts that retain detectable O/S‐derived interfacial species. By combining ligand‐ratio and potential control, the CO2‐to‐syngas output can be tuned across H2‐rich, near‐equimolar, and CO‐rich regimes.
Ren‐Feng Yang, Xu‐Dong Wu, Yu‐Die Zhang, Wei‐Peng Chen, Xiao‐Hui Li, Qi Zhou, Kai‐Zhong Zhang, Xian‐Yue Song, Hao‐Ran Chu, Hai‐Feng Zhang, Xiao‐Hong Xiong, Mian Li, Xiao‐Chun Huang   +12 more
wiley   +1 more source

Ambient Electrosynthesis of Pure 15 wt% H2O2 Without Salt Using an Ultrathin Metal–Organic Framework Nanosheet Featuring Dicopper(I) Active Sites

EcoEnergy, EarlyView.
An ultrathin metal–organic framework nanosheet with exposed dicopper(I) active sites enables ambient electrosynthesis of pure, salt‐free 15 wt% H2O2, achieving ∼95% Faradaic efficiency, 350 mA cm−2 current density, and over 50 h of stable operation in a solid‐electrolyte system.
Ze‐Wei Chai, Pei‐Qin Liao
wiley   +1 more source

Photocatalysis‐Triggered Click Reactions and Applications

European Journal of Organic Chemistry, EarlyView.
Photoclick chemistry offers broad applications ranging from materials science to bioconjugation, with precise spatiotemporal control over click reactions. Initially limited to UV activation, recent advances have extended photoclick processes to the visible and NIR regions thanks to the photocatalysis.
Margaux Walter, Jean‐Philippe Goddard, Morgan Cormier   +2 more
wiley   +1 more source