Results 131 to 140 of about 103,024 (350)

Engineering Bisubstrates to Target m6Am RNA Methyltransferases: Synthesis and Computational Studies

Chemistry – A European Journal, EarlyView.
Use of the convertible nucleoside approach to synthesize m6Am RNA methyltransferase bisubstrates. This methodology allows for the introduction of modifications on the SAM analog moiety and the RNA substrate part, including the introduction of a cap analog by click chemistry.
Yoann Colas, Laurent Le Corre, Mélanie Ethève‐Quelquejeu, Emmanuelle Braud   +3 more
wiley   +1 more source

A Mononuclear Scenario for the Copper‐Catalyzed Monooxygenation of Phenolic Substrates

Chemistry – A European Journal, EarlyView.
ABSTRACT Whereas a dinuclear pathway applies to the monooxygenation of phenols by the type 3 copper enzyme tyrosinase, a mononuclear pathway has been identified for the same reaction in corresponding small‐molecule systems. DFT calculations of five copper model complexes reveal that the latter mechanism is energetically feasible, identifying all ...
Alexander Koch, Antony Memboeuf, Felix Tuczek, Tobias A. Engesser   +3 more
wiley   +1 more source

Synthesis, characterization and thermogravimetric study of Cu(II) adducts with 3- and 4-amino-1,2,4-triazole, 2-mercaptothiazoline and 2-mercaptopyridine [PDF]

Journal of the Serbian Chemical Society, 2006
The adducts CuCl2·(3amt), CuCl2·2(3amt)·2H2O, CuCl2·3(3amt), CuCl2·(4amt), CuCl2·2(4amt), CuCl2·3(4amt)·2H2O, CuCl2·(2mct)·H2O, CuCl2·2(2mct)·2.5H2O, CuCl2·3(2mct)·2H2O, CuCl2·(2mcp) and CuCl2·2(2mcp)·H2O, where 3-amino-1,2,4-triazole = 3amt, 4-amino-1,2,
MOAMEN S. REFAT, ROBSON F. DE FARIAS
doaj  

Synthetic Strategies for Activity‐Based Probes to Decode Ubiquitin‐Like Modifiers

Chemistry – A European Journal, EarlyView.
ABSTRACT Ubiquitin‐like proteins (Ubls) such as SUMO, NEDD8, ISG15, URM1, UFM1, FAT10, ATG8/ATG12, and FUBI are essential regulators of cellular homeostasis, controlling processes from protein stability and trafficking to immune signaling and autophagy.
Saibal Chanda, Alan Pham, SreeNidhi Karnati, Natalia Soto Rodriguez, Alyssa Toner, Wenshe Ray Liu   +5 more
wiley   +1 more source

Iridium Complexes of a Triazole‐Derived Pincer Ligand: Synthesis, Reactivity, and Transfer Dehydrogenation Catalysis

Chemistry – A European Journal, EarlyView.
Ir pincer complexes bearing a triazole architecture in the pincer backbone and O‐ancillary chelating ligands are presented. These were employed in the catalytic transfer dehydrogenation of alkanes as well as of saturated heterocycles. Reactivity of these complexes with silver salts and Lewis acids produced various cationic iridium complexes.
Jesvita Cardozo, Ouchan He, Aaron Prenzlow, Xinyang Peng, Kallol Ray, Thomas Braun   +5 more
wiley   +1 more source

Light‐Induced Anion Translocation to Control Helical Folding in an Artificial Communication System

Chemistry – A European Journal, EarlyView.
Anion‐induced helical folding of an oligomer is controlled indirectly and reversibly by light through anion uptake/release by a photoresponsive receptor. Thus, a light signal is processed into a chemical signal in a communication‐type three‐component supramolecular system.
Indigo M. Bekaert, Suchismita Saha, Julia Villalva, David Villarón, Maxime A. Siegler, Sander J. Wezenberg   +5 more
wiley   +1 more source

A Low‐Symmetry FeII Tetrahedron From a Flexible Tritopic Ligand

Chemistry – A European Journal, EarlyView.
A highly symmetric and flexible tris‐bidentate tritopic ligand forms an S4 meso homoleptic face‐capped FeII tetrahedron near‐quantitatively in acetonitrile. The addition of nitromethane solvent causes partial isomerization of this meso cage to the racemic homochiral tetrahedron, with the complexity of the system being moderated through solvophobic ...
Rosemary J. Goodwin, Nina R. Lawson, Michael G. Gardiner, Jack D. Evans, Paul E. Kruger, Dan Preston   +5 more
wiley   +1 more source

Strain Release of 1‐Azabicyclo[1.1.0]butanes as a Gateway to Highly Functionalized Azetidines: New Strategies and Structural Motifs

Chemistry – A European Journal, EarlyView.
Over the past decade, the interest in azetidines has continuously risen, by virtue of their highly appealing pharmaceutical properties. Monocyclic, spirocyclic, and bridged azetidines can be accessed by leveraging 1‐azabicyclo[1.1.0]butanes as precursors.
Yuri Gelato, Philipp Natho, Marco Colella, Renzo Luisi   +3 more
wiley   +1 more source

Deprotometalation-iodolysis and computed CH acidity of 1,2,3- and 1,2,4-triazoles. Application to the synthesis of resveratrol analogues

, 2015
International audience1-Aryl- and 2-aryl-1,2,3-triazoles were synthesized by N-arylation of the corresponding azoles using aryl iodides. The deprotometalations of 1-phenyl-1,2,3-triazole and -1,2,4-triazole were performed using a 2,2,6,6 ...
Bentabed-Ababsa, Ghenia, Chevallier, Floris, Duval, Raphaël E., Fontanay, Stéphane, Halauko, Yury S., Ivashkevich, Oleg A., Matulis, Vadim E., Mongin, Florence, Nagaradja, Elisabeth, Phillipot, Stéphanie, Roisnel, Thierry, Scalabrini, Mathieu   +11 more
core   +3 more sources

Synthesis and Reactivity of 3‐Aminosydnones in Cycloaddition Reactions With Alkynes

Chemistry – A European Journal, EarlyView.
The synthesis, functionalization, and reactivity as dipoles of 3‐aminosydnones have been investigated. These neglected compounds undergo smooth cycloaddition reactions with strained alkynes, leading to 1‐aminopyrazoles. ABSTRACT We present in this article the synthesis, functionalization, and properties of 3‐aminosydnones, a forgotten class of ...
Apolline Dominic, Timothée D'anfray, Guillaume Force, David‐Alexandre Buisson, Maxime Tricoire, Alexis Leblais, Davide Audisio, Frédéric Taran   +7 more
wiley   +1 more source