Prevalence of cyp51A variants in a US collection of Aspergillus fumigatus clinical isolates and comparative analysis of their contribution to triazole antifungal resistance. [PDF]
J Antimicrob ChemotherGómez Londoño LF +10 more
europepmc +1 more source
The continuing significance of chiral agrochemicals
Pest Management Science, Volume 81, Issue 4, Page 1697-1716, April 2025.In the time frame 2018–2023, around 43% of the 35 chiral agrochemicals introduced to the market (herbicides, fungicides, insecticides, acaricides, and nematicides) contain one or more stereogenic centers in the molecule, and almost 69% of them have been marketed as racemic mixtures of enantiomers or stereoisomers.
Peter Jeschke
wiley +1 more source
Synthesis of 2-Fluoroalkylated Pyridines and Fluoropyridines by Thermal Denitrogenation of <i>N</i>-Fluoroalkyl-1,2,3-triazoles and Cyclization of Ketenimines. [PDF]
J Org ChemVoltrová S, Klepetářová B, Beier P.
europepmc +1 more source
Rapid Communications in Mass Spectrometry, EarlyView.ABSTRACT Rationale To increase the confidentiality level of molecular tags, binary information can be hidden in sequence‐defined oligomers using isobaric monomers including a photo‐sensitive one, which mass can be modified upon light irradiation. Reading such secured data requires light edition prior to MS/MS sequencing, which was investigated here in ...
Clothilde Comby‐Zerbino +3 more
wiley +1 more source
Concurrent Administration of Triazoles with Chemotherapeutic and/or Immunosuppressant Agents Known to Have Moderate-to-Severe Drug-Drug Interactions in Patients with Hematologic Malignancies Hospitalized for Invasive Aspergillosis. [PDF]
MycopathologiaWalsh TJ +4 more
europepmc +1 more source
Advanced design and application for viologen‐based redox devices with customizable functionalities
Responsive Materials, EarlyView.This review examines viologen‐based materials with customizable functionalities achieved through molecular engineering strategies such as side‐chain modification and composite formation. It emphasizes their utility in electrochromic devices, multicolor displays, and energy storage, while discussing stability challenges and outlining future development ...
Yuxin Chang +7 more
wiley +1 more source
The Chemical Record, EarlyView.This review highlights recent advances in the use of organic carbonates, dimethyl carbonate (DMC), diethyl carbonate (DEC), and propylene carbonate (PC), as solvents in organic synthesis. Based on over seventy studies from the past 6 years, it shows their application in different organic reaction types, emphasizing their role in safer and more ...
Gabriela T. Quadros +5 more
wiley +1 more source
Synthesis, Physical and Ion-Conducting Properties of 1,2,3-Triazolium Ionic Liquids. [PDF]
MoleculesAbdelhedi Miladi I +5 more
europepmc +1 more source
Structural insights into the binding mode of the hypnotic drug vornorexant to orexin receptors
Acta Crystallographica Section F, EarlyView.The crystal structure of the human orexin type 2 receptor–vornorexant complex (3.29 Å resolution) and orexin type 1 receptor docking revealed a conserved U‐shaped binding conformation, explaining the high affinity and balanced dual antagonism of this dual orexin receptor antagonist. The structural data validate the rational design that incorporated a 1,
Masashi Mima +4 more
wiley +1 more source
Synthesis of sulfanyl derivatives of 1,2,4-triazoles <i>via</i> an acid catalyzed intramolecular cyclization of isothiosemicarbazones: structural characterization, <i>E</i>/<i>Z</i> isomerism, mechanistic insights and <i>in vitro</i> cytotoxicity. [PDF]
RSC AdvSnisha K +4 more
europepmc +1 more source