Results 181 to 190 of about 49,489 (310)

Carbazole Framework as Functional Scaffold for the Design of Synthetic Receptors

Chemistry – A European Journal, EarlyView.
Carbazole‐based receptors play a crucial role in supramolecular chemistry, due to their unique geometry, photophysical properties, strong hydrogen bonding features, and versatility. This review examines prominent examples, focusing on how structural modifications shape binding affinity and selectivity for various guests, showcasing the potential of ...
Alessio Carioscia, Debora Iapadre, Elena Incerto, Jonathan Di Pietro, Luisa Giansanti, Fabio Pesciaioli, Armando Carlone   +6 more
wiley   +1 more source

Buoyant Density Studies of Chloroplast and Nuclear Deoxyribonucleic Acid from Control and 3-Amino-1,2,4-Triazole-treated Wheat Seedlings, Triticum vulgare [PDF]

, 1970
Paul G. Bartels, Alison Hyde
openalex   +1 more source

Design and Evaluation of Bivalent K‐Ras Inhibitors That Target the CAAX Binding Site and the Acidic Surface of Farnesyltransferase and Geranylgeranyltransferase I

Chemistry – A European Journal, EarlyView.
Chemical inhibition of K‐Ras posttranslational prenylation represents a promising strategy against aggressive cancers. A structure‐based design produces piperidine‐based peptidomimetics conjugated to cationic modules, effectively inhibiting FTase and GGTase I at single‐digit nanomolar concentrations.
Naomi Horiuchi, Rania Omer, Fumitoshi Sugino, Naomi Ogino, Yoshihisa Inoue, Kazi Aslamuzzaman, Takeyuki Suzuki, Said M. Sebti, Junko Ohkanda   +8 more
wiley   +1 more source

Click‐Functionalized Cyanine Fluorogenic Dimers for Improved Detection of GPCRs: Application to Imaging of ApelinR in Living Cells

Chemistry – A European Journal, EarlyView.
A click‐mediated functionalization of a cyanine 5.5 bearing a terminal alkyne gave a rapid access to a library of ten new cyanine dyes and their corresponding dimers. A structure‐interaction relationship study led to the identification of an optimal dimer which was conjugated to the apelin‐17 ligand and enabled imaging of ApelinR under no‐wash ...
Océane Florès, Yann Berthomé, Lucille Weiss, Sarah Griesbaum‐Dubourg, Stéphanie Riché, Patrick Wagner, Christel Valencia, Pascal Villa, Andrey S. Klymchenko, Julie Karpenko, Dominique Bonnet   +10 more
wiley   +1 more source

KEAP1‐NRF2 protein–protein interaction inhibitors: Design, pharmacological properties and therapeutic potential

Medicinal Research Reviews, Volume 43, Issue 1, Page 237-287, January 2023., 2023
Abstract The transcription factor nuclear factor erythroid 2‐related factor 2 (NRF2) is considered the master regulator of the phase II antioxidant response. It controls a plethora of cytoprotective genes related to oxidative stress, inflammation, and protein homeostasis, among other processes.
Enrique Crisman, Pablo Duarte, Esteban Dauden, Antonio Cuadrado, María Isabel Rodríguez‐Franco, Manuela G. López, Rafael León   +6 more
wiley   +1 more source

Exploiting Activated Alkyne Chemistry for the Synthesis of Tailored Amphiphilic Janus Dendrimers with Aggregation‐Induced Emission and Their Assemblies for Cell Imaging

Chemistry – A European Journal, EarlyView.
Amphiphilic Janus dendrimers (AJDs) synthesized via activated alkyne‐hydroxyl “click” chemistry exhibit aggregation‐induced emission (AIE) properties and self‐assemble into fluorescent nanostructures, including dendrimersomes and micelles. These assemblies, with excellent biocompatibility and efficient cellular uptake, demonstrate potential for live ...
Hossein Rasoulmosaedi, Marilyne Bélanger‐Bouliga, Phuong Trang Nguyen, Steve Bourgault, Ali Nazemi   +4 more
wiley   +1 more source

Influence of Protonation and Iron(II) Complexation on Magnetic Interactions in Spin‐Labeled Mechanically Interlocked Molecules

Chemistry – A European Journal, EarlyView.
The study investigates the influence of protonation and Fe(II) complexation on exchange coupling and magnetic properties in a [2]‐rotaxane and its free‐axle biradicals. Mechanical bonding markedly modifies magnetic interactions, highlighting its potential for enabling the design of interlocked molecules with tunable spin states for advanced ...
Lorenzo Gualandi, Anna Turchetti, Paola Franchi, Lorenzo Sorace, Stephen M. Goldup, Fabio Canepa, Gianrico Lamura, Marco Lucarini   +7 more
wiley   +1 more source

Response of Young ‘d’Anjou’ Pear Trees to Triazine and Triazole Herbicides and Nitrogen1 [PDF]

, 1977
J. Thomas Raese
openalex   +1 more source

Synthesis of 6”-triazole-substituted α-GalCer analogues as potent iNKT cell stimulating ligands [PDF]

, 2012
Aspslagh, Banchet-Cadeddu, Bendelac, Berkers, Carnaud, Carvalho, Dirk Elewaut, Ebensen, Galli, Godfrey, Hammond, Hansen, Jervis, Jervis, Kronenberg, Liu, Miyamoto, Morita, Natori, Nora Pauwels, O’Boyle, Pauwels, Sandrine Aspeslagh, Schmieg, Serge Van Calenbergh, Sköld, Smyth, Tashiro, Trappeniers, Tron, Yu, Zhou   +31 more
core   +2 more sources

Advances in Mechanochemical Methods for One‐Pot Multistep Organic Synthesis

Chemistry – A European Journal, Accepted Article.
Mechanochemical synthesis has emerged as a powerful and more sustainable alternative to conventional solution‐based methods, offering advantages such as no or only minimal solvent use, reduced reaction times, and simplified operational conditions.
Michael Schnürch, Nina Biedermann
wiley   +1 more source