Results 11 to 20 of about 75,158 (330)

Understanding the impact of triazoles on female fertility and embryo development: Mechanisms and implications [PDF]

Toxicology Reports
Triazoles are among the most widely used fungicides that were launched in 1980s and are one of the most important pesticide groups used in agriculture as plant growth regulators and stress protectors.
Sonal Sharma, Geeta Pandey
doaj   +2 more sources

Progress and Prospects of Triazoles in Advanced Therapies for Parasitic Diseases [PDF]

Tropical Medicine and Infectious Disease
Parasitic diseases represent a severe global burden, with current treatments often limited by toxicity, drug resistance, and suboptimal efficacy in chronic infections.
Jaime A. Isern, Renzo Carlucci, Guillermo R. Labadie, Exequiel O. J. Porta   +3 more
doaj   +2 more sources

Access to Substituted Tricyclic Heteroarenes by an Oxidative Cyclization Reaction and Their Antifungal Performance [PDF]

Pharmaceuticals
Background/Objectives: Fungal pathogens are increasingly developing concerning resistance against the currently available antifungal drugs, which creates a constant demand for new antifungal agents.
Rehema Nakiwala, Noopur Dasgupta, Rebecca Wilson, Erika I. Lutter, Jeanne L. Bolliger   +4 more
doaj   +2 more sources

LXII.—C-Phenyl-s-triazole [PDF]

J. Chem. Soc., Trans., 1905
n ...
George W. Young
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1,2,4-Triazoles. VII. Methylation of 1,2,4-triazoles.

Chemical and Pharmaceutical Bulletin, 1976
AbstractMethylierung von 1,2,4‐Triazol und dessen symmetrisch 3,5‐disubst.
Masayuki Uda, YUKINORI HISAZUMI, Koji Sato, Seiju Kubota   +3 more
openalex   +5 more sources

Torsade de Pointes/QT Prolongation Associated with Antifungal Triazoles: A Pharmacovigilance Study Based on the U.S. FDA Adverse Event Reporting System（FAERS）

Journal of Pharmacy & Pharmaceutical Sciences, 2022
Purpose: Torsade de pointes (TdP)/QT prolongation is a fatal adverse event (AE) when using antifungal triazoles. We aimed to compare the AE signals of TdP/QT prolongation and onset time among different drugs of this kind comprehensively.
Zicheng Yu, Xiaolan Liao
doaj   +1 more source

Efficacy and safety of triazoles versus echinocandins in the treatment of invasive aspergillosis: A meta-analysis [PDF]

Vojnosanitetski Pregled, 2020
Backgroun/Aim. Although majority of guidelines recommend triazoles (voriconazole, posaconazole, itraconazole and isavuconazole) as first-line therapeutic option for treatment of invasive aspergillosis, echinocandins (caspofungin, micafungin and ...
Uzelac Sanja M., Živković-Zarić Radica S., Radovanović Milan R., Ranković Goran Ž., Jankovic Slobodan M.   +4 more
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Triazoles and Their Derivatives: Chemistry, Synthesis, and Therapeutic Applications

Frontiers in Molecular Biosciences, 2022
Among the nitrogen-containing heterocyclic compounds, triazoles emerge with superior pharmacological applications. Structurally, there are two types of five-membered triazoles: 1,2,3-triazole and 1,2,4-triazole.
Mohammed M. Matin, Priyanka Matin, Md. Rezaur Rahman, Taibi Ben Hadda, Faisal A. Almalki, Shafi Mahmud, Mohammed M. Ghoneim, Maha Alruwaily, Sultan Alshehri   +8 more
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5-Formyltriazoles as Valuable Starting Materials for Unsymmetrically Substituted Bi-1,2,3-Triazoles

Frontiers in Chemistry, 2020
Herein, we present the first synthetic methodologies toward non-symmetrical 5,5′-C, C-linked bi-1,2,3-triazoles starting from 5-formyl-1,2,3-triazole via two related pathways.
Robby Vroemans, Tomas Horsten, Maarten Van Espen, Wim Dehaen   +3 more
doaj   +1 more source

Design and Synthesis of New 5-aryl-4-Arylethynyl-1H-1,2,3-triazoles with Valuable Photophysical and Biological Properties

Molecules, 2021
Cu-catalyzed 1,3-dipolar cycloaddition of methyl 2-azidoacetate to iodobuta-1,3-diynes and subsequent Suzuki-Miyaura cross-coupling were used to synthesize new triazoles derivatives: 5-aryl-4-arylethynyl-1H-1,2,3-triazoles. Investigation of their optical
Mariia M. Efremova, Anastasia I. Govdi, Valeria V. Frolova, Andrey M. Rumyantsev, Irina A. Balova   +4 more
doaj   +1 more source