Results 21 to 30 of about 38,452 (298)

Triazole pesticides exposure impaired steroidogenesis associated to an increase in AHR and CAR expression in testis and altered sperm parameters in chicken

open access: yesToxicology Reports, 2023
Since several decades, we observe the decline of various bird populations that could be partly linked to the agricultural intensification and the use of large amount of pesticides.
Loïse Serra   +11 more
doaj   +1 more source

Ligand Control of Copper-Mediated Cycloadditions of Acetylene to Azides: Chemo- and Regio-Selective Formation of Deutero- and Iodo-Substituted 1,2,3-Triazoles

open access: yes, 2023
The participation of σ-monocopper and σ-bis-copper acetylide in mechanistic pathways for copper-catalyzed cycloaddition (CuAAC) reactions of acetylene with azides was probed by analysis of deuterium distributions in the 1,2,3-triazole product formed by ...
Shanguang Qiu (17707543)   +4 more
core   +1 more source

Three-Component Reactions of CF3 Carbonyls, NaN3, and Amines for the Synthesis of NH-1,2,3-Triazoles

open access: yes, 2021
The development of methods for the assembly of 1,2,3-triazoles is an important topic due to the broad applications of this motif in various scientific fields.
Ge Gao (5909)   +9 more
core   +1 more source

Triazoles Synthesis & Applications as Nonsteroidal Aromatase Inhibitors for Hormone-Dependent Breast Cancer Treatment

open access: yesHeteroatom Chemistry, 2022
In the last few years, nonsteroidal aromatase inhibitors (AIs) have been emerged as promising agents for treating hormone-dependent breast cancer in postmenopausal women because of their inhibitory effect on estrogen synthesis.
Huda R. M. Rashdan, Ihsan A. Shehadi
doaj   +1 more source

Metal-Free Synthesis of 1,5-Disubstituted 1,2,3-Triazoles

open access: yes, 2021
A three-component synthesis of 1,5-disubstituted 1,2,3-triazoles from α-acetyl-α-diazomethane sulfonamides, primary aliphatic amines, and aromatic aldehydes is presented.
Mikhail Krasavin   +9 more
core   +1 more source

Efecto del Butóxido de Piperonilo y Sus Mezclas con Fungicidas Triazoles sobre el Crecimiento In Vitro de Mycosphaerella fijiensis Morelet

open access: yesRevista Tecnológica, 2013
Se evaluó el efecto del Butóxido de Piperonilo (BOP), un conocido sinergista de insecticidas, sobre el crecimiento micelial de Mycosphaerella fijiensis para validar la hipótesis que supone que este compuesto posee un efecto antifúngico debido a sus ...
Daniel Navia   +2 more
doaj   +4 more sources

Copper-Catalyzed Three-Component Tandem Reaction of Alkynes, α‑Diazo Esters, and TMSN3 to Access N‑Substituted 1,2,3-Triazoles

open access: yes, 2023
An efficient copper-catalyzed three-component tandem reaction of alkynes, α-diazo esters, and TMSN3 to construct triazoles has been developed. Through this strategy, a number of diverse N-substituted 1,2,3-triazoles were conveniently obtained in moderate
Yufen Lv (8823398)   +7 more
core   +1 more source

Study of the Two Steps and One-Pot Two-Step Mechanochemical Synthesis of Annulated 1,2,4-Triazoles

open access: yes, 2020
The mechanochemical synthesis of 1,2,4-triazoles by using a planetary ball-mill is studied starting from hydralazine hydrochloride. Excellent conditions were found for achieving total conversion to intermediate hydrazones in a few minutes in the presence
Michel Baron (3526049)   +15 more
core   +1 more source

Synthesis of 6-Amino-5-cyano-1,4-disubstituted-2(1H)-Pyrimidinones via Copper-(I)-catalyzed Alkyne-azide ‘Click Chemistry’ and Their Reactivity

open access: yesMolecules, 2010
In this paper we present the room temperature synthesis of a novel serie of 1,4-disubstituted-1,2,3-triazoles 4a-l by employing the (3 + 2) cycloaddition reaction of pyrimidinones containing alkyne functions with different model azides in the presence of
Fethi Zribi   +5 more
doaj   +1 more source

Efficient, mild synthesis of N-unsubstituted 1,2,3-triazoles from methanolysis of 1-sulfonyl-1,2,3-triazoles

open access: yes, 2018
A small library of diverse N-unsubstituted 1,2,3-triazoles was prepared from the corresponding 1-sulfonyl-1,2,3-triazoles, which were treated only with MeOH at reflux temperature.
Janeth Rodríguez-Florencio (5616011)   +3 more
core   +1 more source

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