Results 41 to 50 of about 37,042 (298)
Click Triazoles for Bioconjugation [PDF]
, 2012 Click Chemistry is a set of rapid, selective and robust reactions that give near-quantitative yield of the desired product in aqueous solutions. The Cu(I)-catalyzed azide-alkyne cycloaddition (CuAAC) that forms 1,4-disubstituted triazoles is a prototypical example of click chemistry that features exquisite selectivity and bioorthogonality-that is, non ...
Tianqing, Zheng +3 more
openaire +2 more sources
Facile One-Pot Parallel Synthesis of 3‑Amino-1,2,4-triazoles
, 2018 A 1,2,4-triazole motif is present in numerous commercialized and investigational bioactive molecules. Despite its importance for medicinal chemistry, there is a lack of convenient combinatorial approaches toward this molecular core.
Sergey E. Pipko (1514257) +10 more
core +1 more source
OrganicsSeveral fluoro phenyl triazoles were synthesized using click chemistry between fluoro phenyl azides and phenyl acetylene. Under ultrasound irradiation, this synthetic procedure was performed with Cu (I) in the presence of 1,10-phenanthroline.
Elisa Leyva +3 more
doaj +1 more source
Molbank, 2023 Copper(I)-catalyzed azide-alkyne cycloaddition was employed to construct biscalixarene assemblies from the calix[4]arene dipropargyl ethers and 4,4′-bis-azidomethylated azobenzene or stilbene.
Ivan Lentin +6 more
doaj +1 more source
, 2016 A copper(I)-catalyzed tandem CuAAC/alkynylation reaction of various alkynes, organic azides, and bromoalkynes to provide rapid access to 5-alkynyl-1,2,3-triazoles has been developed.
Chen-Ho Tung (654283) +4 more
core +1 more source
Molecules, 2021 Wheat is one of the global strategic crops and ranks third in terms of cereals production. Wheat crops are exposed to many fungal infections during their cultivation stages, some of which have the ability to secrete a number of toxic secondary ...
Tamer M. A. Thabit +3 more
doaj +1 more source
Yeast Gcn2 retains activity following humanization of its auto‐phosphorylation region
FEBS Open Bio, EarlyView.Using Saccharomyces cerevisiae as a model to study Gcn2 activation and regulation is limited by the lack of antibodies detecting phosphorylated Gcn2. To overcome this, we engineered Gcn2‐HsC, a yeast Gcn2 variant recognizable by commercial anti‐human phospho‐GCN2 antibodies.
Reuben A. Anderson +2 more
wiley +1 more source
Beilstein Journal of Organic Chemistry, 2015 Propargylamines are popular substrates for triazole formation, but tetrasubstituted variants have required multistep syntheses involving stoichiometric amounts of metal.
Zachary L. Palchak +2 more
doaj +1 more source
, 2022 Significant advances have been achieved for the construction of chiral skeletons containing 1,2,3-triazoles via transition-metal-catalyzed asymmetric azide–alkyne cycloaddition; however, most of them have been limited to terminal alkynes in the synthesis
Long Li +15 more
core +1 more source
Photo‐Degradable Polyester Networks and Multi‐Photon Printed Objects Based on Cyclic Ketene Acetals
Advanced Functional Materials, EarlyView.The current work introduces a photoreversible polyester network derived from radical ring‐opening polymerization of cyclic ketene acetals. It combines photoreversible cross‐linking with initiator‐free multi‐photon printing. Reversible network formation, tunable mechanical properties, and selective degradation highlight its potential as a versatile ...
Till Meissner +5 more
wiley +1 more source