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QSAR Prediction of Aquatic Toxicity of Triazoles and Benzo-Triazoles

2011
Triazoles and benzo-triazoles (TAZ/BTAZ) are potentially hazardous chemicals that adversely affect humans and other non-target species, and are on the list of substances of very high concern (SVHC) in the European regulation of chemicals REACH. TAZ/BTAZ are synthetic molecules used in various industrial processes (to obtain pharmaceuticals and ...
CASSANI, STEFANO   +5 more
openaire   +3 more sources

1,2,4-Triazoles

2008
This chapter provides a critical update on developments in the chemistry of 1,2,4-triazoles over the last decade. 1,2,4-Triazoles have remained the topic of much research, primarily due to their ubiquitous presence in many pharmaceutical agents and, more recently, in other functional materials with uses in engineering as corrosion inhibitors and in ...
N. Jennings, Anthony D.M. Curtis
openaire   +2 more sources

Synthesis of 1-(1,2,4-triazol-3-yl)-1,2,3-triazoles

Chemistry of Heterocyclic Compounds, 1980
1-(1,2,4-Triazol-3-yl)-1,2,3-triazoles were obtained by 1,3-dipolar cycloaddition of 3-azido-1,2,4-triazole to acetylene derivatives.
T. F. Sharamet   +3 more
openaire   +2 more sources

Photolysis of vic-triazoles

Tetrahedron Letters, 1969
Photolytic cleavage of vic-triazole ring when unsubstituted at N, finding phenylacetonitrile production ...
R. Selvarajan, J.H. Boyer
openaire   +2 more sources

A Recent Portrait of Bioactive Triazoles

Current Bioactive Compounds, 2010
Scientists have extensively explored new synthetic routes in order to obtain 1,2,3- and 1,2,4-triazoles as they represent a very interesting class of compounds due to their wide range of biological activities such as antitumor, antiinflammatory, analgesic, antifungal, antibacterial, antiviral, etc.
PIBIRI, Ivana, BUSCEMI, Silvestre
openaire   +3 more sources

Voriconazole: A second-generation triazole

Drugs of Today, 2001
Voriconazole, a derivative of fluconazole, is an antifungal triazole with expanded spectrum of activity against a variety of yeasts and filamentous fungi. It exhibits fungicidal activity against Aspergillus species. Preliminary data from animal models and clinical trials show promise in the treatment of candidiasis and aspergillosis.
Elias K. Manavathu   +1 more
openaire   +2 more sources

Ring-Opening Coupling of Cyclopropanol with 1,2,3-Triazole for the Synthesis of Fused Triazoles

Organic Letters
A radical ring-opening arylation of cyclopropanol with 1,2,3-triazole has been achieved. This synthetic protocol provides straightforward access to a wide range of structurally diverse and chiral 4,5,6,7-tetrahydro[1,2,3]triazolo[1,5-a]pyridines with high efficiency from readily available chiral cyclopropanols.
Yi Wu   +8 more
openaire   +2 more sources

The Chemistry of the Vicinal Triazoles.

Chemical Reviews, 1950
Frederic R. Benson, Walter L. Savell
openaire   +3 more sources

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