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Emerging impact of triazoles as anti-tubercular agent.
European journal of medicinal chemistry, 2022Tuberculosis, a disease of poverty is a communicable infection with a reasonably high mortality rate worldwide. 10 Million new cases of TB were reported with approx 1.4 million deaths in the year 2019. Due to the growing number of drug-sensitive and drug-
Anindra Sharma +3 more
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Comprehensive review on natural pharmacophore tethered 1,2,3‐triazoles as active pharmaceuticals
Chemical Biology and Drug Design, 2022The privileged 1,2,3‐triazole scaffold is drawing researcher's attention due to its widespread applications in diverse fields such as drug discovery (e.g., carboxyamidotriazole), organic synthesis (click‐reaction template), polymeric materials (e.g ...
Aluru Rammohan +4 more
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The chemical record, 2021
The triazole heterocycle is a privileged scaffold in medicinal chemistry, since its structure is present in a large number of biologically active molecules, including several drugs currently in the market.
Luana S. M. Forezi +7 more
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The triazole heterocycle is a privileged scaffold in medicinal chemistry, since its structure is present in a large number of biologically active molecules, including several drugs currently in the market.
Luana S. M. Forezi +7 more
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A decade of advances in the reaction of nitrogen sources and alkynes for the synthesis of triazoles
Coordination Chemistry Reviews, 2020The cyclization reactions of alkynes have become one of the most important and useful methodologies for the preparation of heterocycles. To this end, the association between alkynes and nitrogen sources are versatile substrates for the synthesis of ...
Jose S S Neto, Gilson Zeni
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New Methods for Synthesis of 1,2,3-Triazoles: A Review
Polycyclic aromatic compounds (Print), 20211,2,3-Triazole is one of a pair of isomeric chemical compounds with molecular formula C2H3N3, called triazoles, which have a five-membered ring of two carbon atoms and three nitrogen atoms.
Bakthavatchala Reddy Nemallapudi +6 more
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Recent progress on 1H-1,2,3-triazoles as potential antifungal agents.
Current Topics in Medicinal Chemistry, 2021To overcome ever increasing cases of antifungal resistance and circumventing side effects and drug interactions related with currently available drugs has impelled the need to expedite the process of drug discovery and development of novel antifungals. 1,
Nisha Poonia +4 more
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Flash Vacuum Pyrolysis of Azides, Triazoles, and Tetrazoles
Chemical Reviews, 2017 Curt Wentrup
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Developments in the Application of 1,2,3-Triazoles in Cancer Treatment.
Recent Patents on Anti-Cancer Drug Discovery, 2020BACKGROUND The impact of cancer on modern society cannot be emphasized enough in terms of both economic and human costs. Cancer treatments are known, unfortunately, for their side effects - frequently numerous and severe. Drug resistance is another issue
Katerina I Slavova +4 more
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