Results 281 to 290 of about 103,024 (350)

Synthesis, characterization and application of copper oxide chitosan nanocomposite for green regioselective synthesis of [1,2,3]triazoles.

International Journal of Biological Macromolecules, 2019
Chitosan copper (II) oxide nanocomposite was synthesized, characterized and used to synthesize [1,2,3]triazoles. Nanocomposite was characterized by using FTIR, XRD, FESEM, and EDS techniques, which reflected rough morphology.
K. Khalil, S. Riyadh, Sobhi M. Gomha, I. Ali   +3 more
semanticscholar   +1 more source

Metal-Free Synthesis of Functional 1-Substituted-1,2,3-Triazoles from Ethenesulfonyl Fluoride and Organic Azides.

Angewandte Chemie, 2019
The 1,2,3-triazole group is one of the most important connective linkers and functional aromatic heterocycles in modern chemistry. The boom in growth of 1,4-disubstituted triazole products, in particular, since the early 2000's, can be largely attributed
Marie-Claire Giel, C. Smedley, Emily R. R. Mackie, Taijie Guo, Jiajia Dong, T. P. Soares da Costa, J. Moses   +6 more
semanticscholar   +1 more source

Identification of 1,2,4-triazoles as new thymidine phosphorylase inhibitors: Future anti-tumor drugs.

Bioorganic chemistry (Print), 2019
Thymidine phosphorylase (TP) is over expressed in several solid tumors and its inhibition can offer unique target suitable for drug discovery in cancer.
S. Shahzad, M. Yar, Z. Khan, L. Shahzadi, S. A. Naqvi, Adeem Mahmood, S. Ullah, A. J. Shaikh, T. A. Sherazi, A. T. Bale, Jędrzej Kukułowicz, M. Bajda   +11 more
semanticscholar   +1 more source

Triazole antifungals: A review

Drugs of Today, 2015
Invasive fungal infections and systemic mycosis, whether from nosocomial infection or immunodeficiency, have been on an upward trend for numerous years. Despite advancements in antifungal medication, treatment in certain patients can still be difficult for reasons such as impaired organ function, limited administration routes or poor safety profiles of
L R, Peyton, S, Gallagher, M, Hashemzadeh   +2 more
openaire   +2 more sources

Novel triazole antifungal agents

Expert Opinion on Investigational Drugs, 2000
The risk of opportunistic infections is greatly increased in patients who are immunocompromised due to AIDS, cancer chemotherapy and organ or bone marrow transplantation. Candida albicans is often associated with serious systemic fungal infections, however other Candida species such as Candida krusei, Candida tropicalis and Candida glabrata, as well as
H L, Hoffman, E J, Ernst, M E, Klepser
openaire   +2 more sources

1,2,4-Triazole

2006
[288-88-0] C2H3N3 (MW 69.08) InChI = 1S/C2H3N3/c1-3-2-5-4-1/h1-2H,(H,3,4,5) InChIKey = NSPMIYGKQJPBQR-UHFFFAOYSA-N (transacylating agent used for ester and amide synthesis, especially in peptide synthesis; cyclization reactions; oligonucleotide synthesis) Physical Data: mp 120–121 °C; bp 260 °C (dec above 187 °C); fp 140 
Jean-Claude Gesquière, Christopher S. Siedem   +1 more
openaire   +1 more source

1,2,3-Triazoles. Part II. 4-Amino-5-aminomethyl-1,2,3-triazoles

Journal of the Chemical Society, Perkin Transactions 1, 1973
4-Amino-1-(and 2-)methyl-1,2,3-triazole-5-carbonitrile were made by acidic hydrolysis of 4-dimethylaminomethyleneamino-1-(and 2-)methyl-1,2,3-triazole-5-carbonitrile. These amino-nitriles, and also their known 3-methyl- and 3-benzyl-analogues, were hydrogenated to 4-amino-5-aminomethyl-1-methyl-1,2,3-triazole (1a) and its 2- and 3-methyl- and 3-benzyl ...
openaire   +2 more sources

1,2,3‐Triazoles

ChemInform, 2005
AbstractFor Abstract see ChemInform Abstract in Full Text.
openaire   +1 more source

Synthesis of Triazole Nucleoside Derivatives

Nucleosides, Nucleotides & Nucleic Acids, 2003
AbstractFor Abstract see ChemInform Abstract in Full Text.
Zicheng, Li, Shuhua, Chen, Ning, Jiang, Gang, Cui   +3 more
openaire   +2 more sources

Regioselective Synthesis of Fluorosulfonyl 1,2,3-Triazoles from Bromovinylsulfonyl Fluoride.

Organic Letters, 2018
A regioselective metal-free preparation of 4-fluorosulfonyl 1,2,3-triazoles from organic azides and a hitherto underexplored bromovinylsulfonyl fluoride building block is described.
Joice Thomas, V. Fokin
semanticscholar   +1 more source