Results 271 to 280 of about 103,024 (350)

Synthesis of heterocycles through denitrogenative cyclization of triazoles and benzotriazoles.

Chemistry, 2020
During the past decades there has been considerable growth in the development of denitrogenative reactions of triazole skeletons to construct valuable cyclic compounds, particularly heterocycles.
Wenbo Li, Junliang Zhang
semanticscholar   +1 more source

Recent accomplishments on the synthetic/biological facets of pharmacologically active 1H-1,2,3-triazoles.

European journal of medicinal chemistry, 2020
The continuous demand of medicinally important scaffolds has prompted the synthetic chemists to identify simple and efficient routes for their synthesis.
S. Kumar, Bharvi Sharma, Vishu Mehra, Vipan Kumar   +3 more
semanticscholar   +1 more source

Triazoles in Medicinal Chemistry: Physicochemical Properties, Bioisosterism, and Application.

Journal of Medicinal Chemistry
Triazole demonstrates distinctive physicochemical properties, characterized by weak basicity, various dipole moments, and significant dual hydrogen bond acceptor and donor capabilities.
Qianwen Guan, Shuaishuai Xing, Lei Wang, Jiawei Zhu, Can Guo, Chunlei Xu, Qun Zhao, Yulan Wu, Yao Chen, Haopeng Sun   +9 more
semanticscholar   +1 more source

ChemInform Abstract: 1,2,4‐TRIAZOLE 20. MITT. DIE JODIERUNG VON 1,2,4‐TRIAZOL UND 1,2,3‐TRIAZOL ZU 3,5‐DIJOD‐1,2,4‐TRIAZOL BZW. 4,5‐DIJOD‐1,2,3‐TRIAZOL

Chemischer Informationsdienst. Organische Chemie, 1970
AbstractDurch Erhitzen des Jodtriazols (I) mit dem Dimethyltriazol (II) entstehen die Jodtriazole (III) ( 15% Ausbeute) und (IV) (30%).
RALF MIETHCHEN, HELGA ALBRECHT, EDELTRAUD RACHOW   +2 more
openaire   +1 more source

Structural modification strategies of triazoles in anticancer drug development.

European journal of medicinal chemistry
The triazole functional group plays a pivotal role in the composition of biomolecules with potent anticancer activities, including numerous clinically approved drugs. The strategic utilization of the triazole fragment in the rational modification of lead
Qianwen Guan, Ziming Gao, Yuting Chen, Can Guo, Yao Chen, Haopeng Sun   +5 more
semanticscholar   +1 more source

Beyond click chemistry – supramolecular interactions of 1,2,3-triazoles

Chemical Society Reviews, 2014
Ulrich S Schubert
exaly   +2 more sources

5-Fluoro-1H-indole-2,3-dione-triazoles- synthesis, biological activity, molecular docking, and DFT study

Journal of Molecular Structure, 2020
An environmental friendly heterogeneous catalyst Cell-CuI-NPs was employed for the synthesis of biologically promising 1-((1-aryl)-1H-1,2,3-triazol-4-yl)methyl-5-fluoroindoline-2,3-diones via CuAAC click reaction of 5-fluoro-(1-prop-2-ynyl)indoline-2,3 ...
Sonal Deswal, Naveen, Ram Kumar Tittal, D. Vikas, Kashmiri Lal, Ashwani Kumar   +5 more
semanticscholar   +1 more source

Mesoionic 1,2,3-Triazoles and 1,2,3-Triazole Carbenes

2014
Routine access to 1,2,3-triazoles through the copper-catalyzed azide-alkyne “click” cycloaddition reaction has promoted the rapid development of 1,2,3-triazolylidenes as ligands for transition metals. The organometallic complexes containing this kind of N-heterocyclic carbene ligands (NHCs) have shown to possess unique structural characteristics ...
Jesus M. Aizpurua, Maialen Sagartzazu-Aizpurua, Zaira Monasterio   +2 more
openaire   +1 more source

Copper(I)‐Catalyzed Interrupted Click Reaction: Synthesis of Diverse 5‐Hetero‐Functionalized Triazoles

Angewandte Chemie - International Edition, 2016
Chen-Ho Tung, Zhenghu Xu
exaly   +2 more sources

Usnic Acid Enaminone-Coupled 1,2,3-Triazoles as Antibacterial and Antitubercular Agents.

Journal of Natural Products, 2019
(+)-Usnic acid, a product of secondary metabolism in lichens, has displayed a broad range of biological properties such as antitumor, antimicrobial, antiviral, anti-inflammatory, and insecticidal activities. Interested by these pharmacological activities
P. Bangalore, S. K. Vagolu, R. K. Bollikanda, Dileep K. Veeragoni, P. Choudante, S. Misra, D. Sriram, B. Sridhar, S. Kantevari   +8 more
semanticscholar   +1 more source