Type A Trichothecene Metabolic Profile Differentiation, Mechanisms, Biosynthetic Pathways, and Evolution in Fusarium Species—A Mini Review [PDF]
Toxins, 2023 Trichothecenes are the most common Fusarium toxins detected in grains and related products. Type A trichothecenes are among the mycotoxins of greatest concern to food and feed safety due to their high toxicity.
Jianhua Wang +5 more
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Phylogenetic Variation of Tri1 Gene and Development of PCR–RFLP Analysis for the Identification of NX Genotypes in Fusarium graminearum Species Complex [PDF]
Toxins, 2023 NX toxins have been described as a novel group of type A trichothecenes produced by members of the Fusarium graminearum species complex (FGSC). Differences in structure between NX toxins and the common type B trichothecenes arise from functional ...
Meiling Gao +5 more
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Regulatory mechanism of trichothecene biosynthesis in Fusarium graminearum [PDF]
Frontiers in Microbiology, 2023 Among the genes involved in the biosynthesis of trichothecene (Tri genes), Tri6 and Tri10 encode a transcription factor with unique Cys2His2 zinc finger domains and a regulatory protein with no consensus DNA-binding sequences, respectively.
Maydelene Xiao Xuan Liew +4 more
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Precocene II, a Trichothecene Production Inhibitor, Binds to Voltage-Dependent Anion Channel and Increases the Superoxide Level in Mitochondria of Fusarium graminearum. [PDF]
PLoS ONE, 2015 Precocene II, a constituent of essential oils, shows antijuvenile hormone activity in insects and inhibits trichothecene production in fungi. We investigated the molecular mechanism by which precocene II inhibits trichothecene production in Fusarium ...
Tomohiro Furukawa +5 more
doaj +2 more sources
Proinflammatory cytokines interleukin-18 and interleukin-6 mediate anorexia induction by trichothecene deoxynivalenol and its congeners [PDF]
Frontiers in Veterinary ScienceAs the common foodborne mycotoxins with the highest pollution rate, deoxynivalenol (DON, also named “vomitoxin”) can harm the health of humans and animals by causing anorectic response.
Chuang Zhou +8 more
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Reduction of Fusarium head blight and trichothecene contamination in transgenic wheat expressing Fusarium graminearum trichothecene 3-O-acetyltransferase [PDF]
Frontiers in Plant ScienceFusarium graminearum, the causal agent of Fusarium head blight (FHB), produces various mycotoxins that contaminate wheat grains and cause profound health problems in humans and animals.
Gabdiel Yulfo-Soto +7 more
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Pathological consequences, metabolism and toxic effects of trichothecene T-2 toxin in poultry [PDF]
Poultry Science: Contamination of feed with mycotoxins has become a severe issue worldwide. Among the most prevalent trichothecene mycotoxins, T-2 toxin is of particular importance for livestock production, including poultry posing a significant threat to animal health
Júlia Vörösházi +3 more
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Microorganisms, 2022 The Fusarium graminearum species complex is the main causal agent of wheat head blight worldwide. Trichothecenes produced by the pathogen in infected grains have important food safety implications.
Jianhua Wang +7 more
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Cellular development associated with induced mycotoxin synthesis in the filamentous fungus Fusarium graminearum. [PDF]
PLoS ONE, 2013 Several species of the filamentous fungus Fusarium colonize plants and produce toxic small molecules that contaminate agricultural products, rendering them unsuitable for consumption. Among the most destructive of these species is F.
Jon Menke +3 more
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AN IN VITRO ESTIMATION OF CYTOTOXICITY OF FUSARIUM TRICHOTHECENE ON THE BREAST CANCER CELL LINE
Сибирский онкологический журнал, 2020 trichothecenes and their derivatives have recently attracted much attention of researchers with respect of their potential role in medicine, including for the treatment of different types of cancer.
Rin. S. Mukhammadiev +6 more
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