Results 51 to 60 of about 15,217 (246)
In trichothecene-producing fusaria, isotrichodermol (ITDol) is the first intermediate with a trichothecene skeleton. In the biosynthetic pathway of trichothecene, a 3-O-acetyltransferase, encoded by Tri101, acetylates ITDol to a less-toxic intermediate ...
Nozomu Tanaka+8 more
doaj +1 more source
Identification and Characterization of Small Molecule Compounds That Modulate Trichothecene Production by Fusarium graminearum [PDF]
From the RIKEN Natural Products Depository (NPDepo) chemical library, we identified small molecules that alter trichothecene 15-acetyldeoxynivalenol (15-ADON) production by Fusarium graminearum. Among trichothecene production activators, a furanocoumarin
85359+19 more
core +1 more source
Effects of four Fusarium toxins (fumonisin B(1), alpha-zearalenol, nivalenol and deoxynivalenol) on porcine whole-blood cellular proliferation. [PDF]
The in vitro effects of four Fusarium toxins, fumonisin B1 (FB1), a-zearalenol (a-ZEA), nivalenol (NIV) and deoxynivalenol (DON), on mitogen-induced cell proliferation were determined in swine whole-blood cultures.
DE LUNA, ROCCO+3 more
core +1 more source
Detection of T-2 Toxin in Wheat and Maize with a Portable Mass Spectrometer
T-2 toxin is a mycotoxin routinely found as a contaminant of cereal grains worldwide. A portable mass spectrometer was adapted to enable the detection of T-2 toxin in wheat and maize by APCI-MS.
Chris M. Maragos
doaj +1 more source
Deficient Glutathione in the Pathophysiology of Mycotoxin-Related Illness
Evidence for the role of oxidative stress in the pathophysiology of mycotoxin-related illness is increasing. The glutathione antioxidant and detoxification systems play a major role in the antioxidant function of cells.
Frederick T. Guilford, Janette Hope
doaj +1 more source
The existence of di-glucosylated derivative of T-2 toxin in plant (corn powder) was confirmed for the first time in addition to that of HT-2 toxin. These masked mycotoxins (mycotoxin glucosides) were identified as T-2 toxin-di-glucoside (T2GlcGlc) and HT-
Hitoshi Nagashima+3 more
doaj +1 more source
Trichothecene toxins are confirmed or suspected virulence factors of various plant-pathogenic Fusarium species. Plants can detoxify these to a variable extent by glucosylation, a reaction catalyzed by UDP-glucosyltransferases (UGTs).
H. Michlmayr+11 more
semanticscholar +1 more source
Hydrogen-Bonding Interactions in T-2 Toxin Studied Using Solution and Solid-State NMR
The structure of T-2 toxin in the solid-state is limited to X-ray crystallographic studies, which lack sufficient resolution to provide direct evidence for hydrogen-bonding interactions.
Paul Hazendonk+6 more
doaj +1 more source
Macrocyclic Trichothecene Mycotoxins from a Deadly Poisonous Mushroom, Podostroma cornu-damae.
Three new macrocyclic trichothecenes (1-3) and five known related compounds (4-8) were isolated from the MeOH extract of a plate culture of the fungus Podostroma cornu-damae, a deadly poisonous mushroom. Miophytocen D (1) is a rearranged macrocyclic type
Seoung Rak Lee+4 more
semanticscholar +1 more source
Summary The ubiquitous filamentous fungus F usarium graminearum causes the important disease Fusarium head blight on various species of cereals, leading to contamination of grains with mycotoxins. In a survey of F .
E. Varga+13 more
semanticscholar +1 more source