Results 31 to 40 of about 1,630 (179)
Annals of Indian Academy of Neurology, 2022 Background: Most centers in developing countries prefer chelation therapy with D-penicillamine for the management of Wilson's disease (WD) because of its easy availability and affordability. Neurological worsening following treatment with D-penicillamine
Madhan Kumar +5 more
doaj +1 more source
Catatonia: A rare presentation of Wilson's disease
Industrial Psychiatry Journal, 2021 Wilson's disease (WD) or hepatolenticular degeneration is a rare inherited disorder of copper metabolism affecting both the liver and the central nervous system.
Supriya Davis +4 more
doaj +1 more source
Toxicology International, 2015 Wilson disease is a rare genetic hepatic and neurological disorder of copper accumulation. Trientine is usually used as a second line in the management of patients with this condition. We present a case of a large overdose of Trientine (60 g) resulting in self-limiting dizziness and vomiting with no further clinical sequelae or significant biochemical ...
Hashim, Ahmed, Parnell, Nick
openaire +3 more sources
BMC Chemistry, 2023 Trientine or (N,N´-bis(2-aminoethyl)-1,2-ethanediamine (TETA) is a copper chelator and used in Wilson’s disease, is aliphatic amine that does not have UV absorbing groups.
Mahsa Khodadadi, Ali Shayanfar
doaj +1 more source
Sensitive and Rapid determination of Trientine and N1-Acetyl Trientine in Human Plasma by LC-MS/MS for bioequivalence study [PDF]
, 2019 A simple and robust method for simultaneous determination of Trientine and N1-Acetyl Trientine in human plasma by liquid chromatography-tandem mass spectrometry (LC-MS/MS) was developed and validated. The analyte and internal standard were extracted from
Parmar, Dharmesh +4 more
core +1 more source
Romanian Journal of Neurology, 2011 A disturbance of copper metabolism causes hepatolenticular degeneration (Wilson’s disease), an autosomal recessive disorder whose genetic locus lies on the long arm of chromosome 13.
A. Hancu +5 more
doaj +1 more source
Frontiers in Oncology, 2019 Background: Epithelial ovarian cancer (EOC) is the leading cause of gynecological cancer-related deaths worldwide. Preclinical studies found that copper-lowering agents could re-sensitize platinum-resistant cancer cells by enhancing the human copper ...
Yu-Fang Huang +5 more
doaj +1 more source
Switching Pharmacological Treatment in Wilson Disease: Case Report and Recommendations
Journal of Investigative Medicine High Impact Case Reports, 2020 Background . Available treatments for Wilson disease (WD) prevent longterm complications of copper accumulation. Current anti-copper agents include zinc salts, penicillamine, and trientine.
Marcia Leung MD +2 more
doaj +1 more source
Pharmaceuticals, 2021 The platinum (Pt)-containing antitumor drugs including cisplatin (cis-diamminedichloroplatinum II, cDDP), carboplatin, and oxaliplatin, have been the mainstay of cancer chemotherapy. These drugs are effective in treating many human malignancies.
Macus Tien Kuo +3 more
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Wilson disease in Northern Portugal: a long-term follow-up study
Orphanet Journal of Rare Diseases, 2022 Introduction Wilson disease is an autosomal recessive disease of liver copper metabolism with predominant hepatic and neurological manifestations. Long-term data on the clinical follow-up and treatment efficacy are limited due to the low frequency of the
Isabel Garrido +5 more
doaj +1 more source