Results 41 to 50 of about 1,630 (179)
, 2021 Background: Disturbances of copper (CU) homeostasis can lead to hypertrophic cardiac phenotypes (e.g. Wilson’s disease). We previously identified abnormal Cu homeostasis in patients with hypertrophic cardiomyopathy (HCM) and therefore hypothesized that ...
Cooper, G. +7 more
core +4 more sources
Trientine-induced Rhabdomyolysis in an Adolescent with Wilson's Disease
, 2019 WOS: 000496525900012PubMed ID: 31749561Background: Drugs are very important in the etiology of nontraumatic rhabdomyolysis. Case descriptions: A 16-year-old male patient with Wilson's disease was admitted for myoclonic contractions.
Coban, Yasemin +6 more
core +1 more source
Case Report: The Association of Wilson Disease in a Patient With Ataxia and GLUT-1 Deficiency
Frontiers in Pediatrics, 2021 Background: Wilson disease (WD) and glucose transporter type 1 (GLUT1) deficiency syndrome are two syndromes with different modes of inheritance but share certain similarities on neurological presentation. To date we have not found previous reports of an
Jenna Diaz +7 more
doaj +1 more source
Frontiers in HematologyWe present a rare case of erythrocytosis due to a homozygous SLC30A10 mutation, causative of Hypermanganesemia with Dystonia, Polycythemia, and Cirrhosis (HMDPC).
Tiziana Coppola +13 more
doaj +1 more source
THE INHIBITORY EFFECT OF COPPER-CHELATOR, TRIENTINE, ON LIVER TUMOR GROWTH AND ON HEPATOCARCINOGENESIS BY ANGIOGENESIS SUPPRESSION [PDF]
, 2004 Angiogenesis is now recognized to play a pivotal role in tumor development, and even in the process of carcinogenesis. Trientine dihydrochloride (trientine) is used in clinical practice as a copper (Cu)-chelating agent.
吉井, 純一
core +1 more source
Therapeutic Reversal of Severe Neuropsychiatric Symptoms in Wilson's Disease: A Case Report
Clinical Case Reports, Volume 14, Issue 11, November 2026.ABSTRACT Wilsons disease is an autosomal recessive genetic disorder of copper metabolism that results in copper accumulation in liver and other organs. Hepatic manifestation tends to occur earlier than the neurological manifestation. We present a case with psychiatric presentation.
Tshering Penjor +2 more
wiley +1 more source
Journal of the Formosan Medical Association, 2018 Background/Purpose: This study aimed to investigate the epidemiology, the preference of medication, and the potential outcome of Wilson disease in Taiwan.
Chi-San Tai +5 more
doaj +1 more source
DBT Modulates Copper‐Dependent Cuproptosis‐Related Injury in Experimental Alcoholic Cardiomyopathy
Journal of Cellular and Molecular Medicine, Volume 30, Issue 21, November 2026.ABSTRACT Alcoholic cardiomyopathy (ACM) is a severe cardiovascular complication of chronic alcohol consumption, but its underlying mechanisms remain incompletely understood. Cuproptosis is a recently identified copper‐dependent form of regulated cell death; however, its role in ACM remains unclear.
Zhihao Pan +3 more
wiley +1 more source
Iron and Other Metal Ions in Human Health and Disease
MedComm, Volume 7, Issue 10, October 2026.Iron, copper, zinc, and calcium orchestrate cellular function through distinct yet cooperative mechanisms: redox‐active iron and copper cycle between oxidation states to act as Fenton catalysts and electron carriers in oxidative phosphorylation (OXPHOS); redox‐inert zinc serves as a structural component of zinc‐finger proteins and a catalytic cofactor ...
Xiaofeng Dai, Jitian Li
wiley +1 more source
Treatment patterns in a real-world cohort of patients with Wilson disease in the United States
Frontiers in GastroenterologyBackgroundWilson disease (WD) is a rare and potentially fatal genetic disorder caused by accumulation of toxic levels of copper. Current treatments include chelating agents and/or zinc.
Valentina Medici +4 more
doaj +1 more source