Results 31 to 40 of about 22,737 (222)

Spin-electric coupling in quantum dots and molecular magnets [PDF]

open access: yes, 2011
In this thesis we study several aspects related to the dynamics of electrons and holes in quantum dots, as well as dynamics of electron spins in molecular magnets.
Trif, Mircea
core   +1 more source

Adaptor Molecule TRIF in Teleost

open access: yesJournal of Clinical Medicine Research, 2020
The immune defense mechanism mainly depends on the recognition and response of innate immune signaling receptors PRRs to PAMPs or DAMPs. TLRs family is an important category in PRRs, stimulatory cytokines and interferon type I (IFN) are produced through TRIF-or MyD88-dependent after TLRs recognition PAMPs or DAMPs, which regulate innate and adaptive ...
Guanjie Wang, Guobin Hu
openaire   +2 more sources

Delayed Resolution of Acute Inflammation in Ulcerative Colitis Is Associated with Elevated Cytokine Release Downstream of TLR4 [PDF]

open access: yes, 2010
Background: Ulcerative colitis (UC) is widely viewed as a leukocyte-mediated disorder. Although strong evidence implicates an exuberant response to microbial components in its pathogenesis, no intrinsic immune defect has been identified and the ...
Bu'Hussain Hayee   +17 more
core   +2 more sources

A study of the modulation of Toll-like receptor signalling in macrophages by Annexin-1 [PDF]

open access: yes, 2011
PhDAnnexin-A1 (AnxA1) is an endogenous anti-inflammatory protein that has been shown to exert a protective role against the lethal effects induced by the Toll-like receptor (TLR) 4 agonist lipopolysaccharide (LPS).
Polycarpou, Anastasia
core   +4 more sources

The ubiquitin-like protein PLIC-1 or ubiquilin 1 inhibits TLR3-Trif signaling. [PDF]

open access: yesPLoS ONE, 2011
The innate immune responses to virus infection are initiated by either Toll-like receptors (TLR3/7/8/9) or cytoplasmic double-stranded RNA (dsRNA)-recognizing RNA helicases RIG-I and MDA5.
Nabanita Biswas   +6 more
doaj   +1 more source

circMORC3-encoded novel protein negatively regulates antiviral immunity through synergizing with host gene MORC3.

open access: yesPLoS Pathogens, 2023
The protein-coding ability of circRNAs has recently been a hot topic, but the role of protein-coding circRNAs in antiviral innate immunity of teleost fish has rarely been reported.
Linchao Wang   +4 more
doaj   +1 more source

Microglial TIR-domain-containing adapter-inducing interferon-β (TRIF) deficiency promotes retinal ganglion cell survival and axon regeneration via nuclear factor-κB

open access: yesJournal of Neuroinflammation, 2012
Background TIR-domain-containing adapter-inducing interferon-β (TRIF) is the sole downstream adaptor of Toll-like receptor (TLR)3, which is one of the major signaling pathways in immune cells leading to neuroinflammation in the central nervous system ...
Lin Sen   +8 more
doaj   +1 more source

TRIF Regulates BIC/miR-155 via the ERK Signaling Pathway to Control the ox-LDL-Induced Macrophage Inflammatory Response

open access: yesJournal of Immunology Research, 2018
Toll/IL-1R-domain-containing adaptor-inducing IFN-β (TRIF) is an important adaptor for TLR3- and TLR4-mediated inflammatory signaling pathways. Recent studies have shown that TRIF plays a key role in vessel inflammation and atherosclerosis; however, the ...
Yaxi Wu   +4 more
doaj   +1 more source

Beyond MyD88 and TRIF Pathways in Toll-Like Receptor Signaling [PDF]

open access: yesFrontiers in Immunology, 2014
The Toll-like receptors (TLRs), 13 types known to-date, are a major class of transmembrane proteins of the mammalian innate immune system (1). They are known to detect diverse pathogen-associated molecular patterns of microorganisms, and trigger specialized sets of signal transduction cascades that neutralize any danger posed to the host by the ...
Vincent ePiras   +3 more
openaire   +3 more sources

MORC3-84aa promotes K6-linked ubiquitination of TRIF.

open access: yes, 2023
(A) HEK293 cells were transfected with TRIF-Myc, Linear-Flag-MORC3-84aa, or pcDNA3.1 and His-Ub-WT, His-Ub-K6O, His-Ub-K11O, His-Ub-K27O, His-Ub-K29O or His-Ub-K33O.
Weiwei Zheng (140828)   +4 more
core   +1 more source

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