Results 111 to 120 of about 271 (121)

Biochemical insight into soman intoxication and treatment with atropine, HI-6, trimedoxime, and K203 in a rat model.

Bratislavske lekarske listy, 2011
The present experiment is based on biochemical assessment of nerve agent soman intoxication and atropine, respectively atropine and HI-6, trimedoxime or K203 treatment in rats.Nerve agents are toxic substances irreversibly inhibiting enzyme acetylcholinesterase (AChE).
M, Pohanka, J, Pikula, K, Kuca, J, Kassa
openaire   +1 more source

Application of modeling for evaluation of the efficacy of trimedoxime, atropine and sodium bicarbonate against dichlorvos poisoning in rats

2006
IV Kongres farmaceuta Srbije sa međunarodnim učešćem, 29. novembar – 2.
Stefanović, D., Antonijević, Biljana, Bokonjić, Dubravko, Milovanović, Zoran A., Stojiljković, Miloš P., Nedeljković, M.   +5 more
openaire   +1 more source

Oxidative stress during soman intoxication and treatment with atropine, asoxime, trimedoxime and K203 in a rat model

Toxicology Letters, 2010
M. Pohanka, M. Mercova, J.Z. Karasova, K. Kuca, J. Pikula, J. Kassa   +5 more
openaire   +1 more source

Understanding the Interaction Modes and Reactivity of Trimedoxime toward MmAChE Inhibited by Nerve Agents: Theoretical and Experimental Aspects

International Journal of Molecular Sciences, 2020
Kamil Kuca, Teodorico C Ramalho, Eugenie Nepovimova   +2 more
exaly  

Pharmacokinetic study of two acetylcholinesterase reactivators, trimedoxime and newly synthesized oxime K027, in rat plasma

Journal of Applied Toxicology, 2013
Kamil Kuca, Miloš Hroch, Jaroslav Chládek   +2 more
exaly  

Comparative studies of pralidoxime, trimedoxime, obidoxime and diethyxime in acute fluostigmine poisoning in rats.

Die Pharmazie, 1983
S, Das Gupta, A K, Ghosh, M V, Moorthy, D K, Jaiswal, B L, Chowdhri, , Purnand, B P, Pant   +6 more
openaire   +1 more source

The evaluation of the reactivating and therapeutic efficacy of three novel bispyridinium oximes (K454, K456, K458) in comparison with the oxime K203 and trimedoxime in tabun-poisoned rats and mice

Toxicology Mechanisms and Methods, 2013
Jiří Kassa, Vendula Sepsova, Kamil Musilek   +2 more
exaly  

[Effect of atropine and trimedoxime on the acetylcholinesterase activity in some parts of the mouse brain].

Ceskoslovenska farmacie, 1971
J, Bajgar, A, Jakl, V, Hrdina
openaire   +1 more source

A comparison of reactivating and therapeutic efficacy of the oxime K203 and its fluorinated analog (KR-22836) with currently available oximes (obidoxime, trimedoxime, HI-6) against tabun in rats and mice

Journal of Enzyme Inhibition and Medicinal Chemistry, 2010
Young-Sik Jung, Kamil Kuca, Jiří Kassa   +2 more
exaly  

[Microcristallographic identification of some antidotes: pralidoxime, trimedoxime and obidoxime (author's transl)].

Journal de pharmacie de Belgique, 1978
openaire   +1 more source