Results 101 to 110 of about 553,444 (284)

On the Road to Accurate Biomarkers for Cardiometabolic Diseases by Integrating Precision and Gender Medicine Approaches [PDF]

, 2019
The need to facilitate the complex management of cardiometabolic diseases (CMD) has led to the detection of many biomarkers, however, there are no clear explanations of their role in the prevention, diagnosis or prognosis of these diseases.
Argano, Vincenzo, Balistreri, Carmela Rita, Giarratana, Rosa Maria, Lio, Domenico, Scola, Letizia, Torre, Salvatore   +5 more
core   +1 more source

Evidence of a causal and modifiable relationship between kidney function and circulating trimethylamine N-oxide

Nature Communications, 2023
The host-microbiota co-metabolite trimethylamine N-oxide (TMAO) is linked to increased cardiovascular risk but how its circulating levels are regulated remains unclear.
P. Andrikopoulos, J. Aron‐Wisnewsky, R. Chakaroun, A. Myridakis, S. Forslund, T. Nielsen, S. Adriouch, Bridget Holmes, J. Chilloux, S. Vieira-Silva, G. Falony, Joe-Elie Salem, Fabrizio Andreelli, Eugeni Belda, J. Kieswich, K. Chechi, F. Puig-Castellví, Mickaël Chevalier, E. Le Chatelier, M. Olanipekun, Lesley Hoyles, Renato J Alves, Gérard Helft, R. Isnard, L. Køber, Luis Pedro Coelho, C. Rouault, Dominique Gauguier, J. Gøtze, Edi Prifti, P. Froguel, Jean-Daniel Zucker, F. Bäckhed, H. Vestergaard, T. Hansen, J. Oppert, M. Blüher, Jens Nielsen, J. Raes, P. Bork, Muhammad M. Yaqoob, M. Stumvoll, Oluf Pedersen, S. Ehrlich, Karine Clément, M. Dumas   +45 more
semanticscholar   +1 more source

From Two‐Electron to Four‐Electron System: Electrolyte Regulation for Advanced Aqueous Zn–I2 Batteries

Carbon Energy, EarlyView.
This review systematically summarizes recent progress in electrolyte‐regulated aqueous Zn–I2 batteries (AZIBs). It outlines the fundamentals of AZIBs along with their main challenges, and then analyzes electrolyte‐engineering strategies that improve both two‐ and four‐electron reactions.
Yucong Wang, Ruifeng Huang, Zhangchi Yang, Shaojian Zhang, Lijing Yan, Weijie Chen, Xiaolong Lin, Yongjun Li, Shuxing Wu, Zhan Lin, Jun Lu   +10 more
wiley   +1 more source

Structural mechanism for bacterial oxidation of oceanic trimethylamine into trimethylamine N -oxide [PDF]

, 2017
Trimethylamine (TMA) and trimethylamine N-oxide (TMAO) are widespread in the ocean and are important nitrogen source for bacteria. TMA monooxygenase (Tmm), a bacterial flavin-containing monooxygenase (FMO), is found widespread in marine bacteria and is ...
Chen, Xiu-Lan, Chen, Yin, Li, Chun-Yang, Li, Ping-Yi, Peng, Ming, Qin, Qi-Long, Sheng, Qi, Shi, Mei, Song, Xiao-Yan, Su, Hai-Nan, Wang, Peng, Xie, Bin-Bin, Xun, Lu-Ying, Zhang, Dian, Zhang, Xi-Ying, Zhang, Yu-Zhong, Zhou, Bai-Cheng   +16 more
core   +1 more source

Systemic aging fuels heart failure: Molecular mechanisms and therapeutic avenues

ESC Heart Failure, Volume 12, Issue 2, Page 1059-1080, April 2025.
Abstract Systemic aging influences various physiological processes and contributes to structural and functional decline in cardiac tissue. These alterations include an increased incidence of left ventricular hypertrophy, a decline in left ventricular diastolic function, left atrial dilation, atrial fibrillation, myocardial fibrosis and cardiac ...
Zhuyubing Fang, Umar Raza, Jia Song, Junyan Lu, Shun Yao, Xiaohong Liu, Wei Zhang, Shujuan Li   +7 more
wiley   +1 more source

Gut microbiota‐related modulation of immune mechanisms in post‐infarction remodelling and heart failure

ESC Heart Failure, Volume 12, Issue 2, Page 942-954, April 2025.
Abstract The immune system has long been recognized as a key driver in the progression of heart failure (HF). However, clinical trials targeting immune effectors have consistently failed to improve patient outcome across different HF aetiologies. The activation of the immune system in HF is complex, involving a broad network of pro‐inflammatory and ...
Johann Roessler, Friederike Zimmermann, Bettina Heidecker, Ulf Landmesser, Arash Haghikia   +4 more
wiley   +1 more source

Trimethylamine N-Oxide: The Good, the Bad and the Unknown

Toxins, 2016
Trimethylamine N-oxide (TMAO) is a small colorless amine oxide generated from choline, betaine, and carnitine by gut microbial metabolism. It accumulates in the tissue of marine animals in high concentrations and protects against the protein ...
Manuel T. Velasquez, Ali Ramezani, Alotaibi Manal, Dominic S. Raj   +3 more
doaj   +1 more source

Trimethylamine-N-oxide is an independent risk factor for hospitalization events in patients receiving maintenance hemodialysis

Renal Failure, 2020
Background Hospitalization is a significant outcome measurement for maintenance hemodialysis pantients. Trimethylamine-N-oxide (TMAO), created by gut microflora from dietary l-carnitine and choline, cleared by the kidney, has been implicated in the ...
Yin Zheng, Zihui Tang, Li You, Yuanhao Wu, Junfeng Liu, Jun Xue   +5 more
doaj   +1 more source

The search for biomarkers of facial eczema, following a sporidesmin challenge in dairy cows, using mass spectrometry and nuclear magnetic resonance of serum, urine, and milk : a thesis presented in partial fulfilment of the requirements for the degree of Doctor of Philosophy in Sciences at Massey University, Palmerston North, Manawatu, New Zealand [PDF]

, 2015
Facial eczema (FE) is a secondary photosensitisation disease of ruminants that is significant in terms of both its economic importance to New Zealand and its impact on animal welfare.
Matthews, Zoe Maree
core  

Seasonal changes in microbial dissolved organic sulfur transformations in coastal waters [PDF]

, 2020
The marine trace gas dimethylsulfide (DMS) is the single most important biogenic source of atmospheric sulfur, accounting for up to 80% of global biogenic sulfur emissions.
Dixon, Joanna L., Hopkins, Frances E., Schäfer, Hendrik, Stephens, John A.   +3 more
core   +1 more source