Results 21 to 30 of about 56,477 (262)

Purification and properties of a catalytically active fragment of soluble nucleoside triphosphatase from bovine kidney [PDF]

open access: yesThe Ukrainian Biochemical Journal, 2013
A catalytic fragment of soluble NTPase has been isolated from bovine kidneys.The 236-fold purification was carried out to obtain the preparation with a specific activity of 37.7 U/mg of protein.
А. F. Makarchikov
doaj   +1 more source

Complete genome sequence and taxonomic position of anguillid herpesvirus 1 [PDF]

open access: yes, 2010
Eel herpesvirus or anguillid herpesvirus 1 (AngHV1) frequently causes disease in freshwater eels. The complete genome sequence of AngHV1 and its taxonomic position within the family Alloherpesviridae were determined. Shotgun sequencing revealed a 249 kbp
Abma-Henkens, M.H.C.   +8 more
core   +9 more sources

Effects of benzo(a)pyrene exposure on the ATPase activity and calcium concentration in the hippocampus of neonatal rats

open access: yesInternational Journal of Occupational Medicine and Environmental Health, 2017
Objectives: To investigate whether postnatal benzo(a)pyrene (B(a)P) exposure caused the impairments on the process of neurodevelopment and the alteration in the calcium medium in the neonatal rats. Material and Methods: Eighty neonatal Sprague Dawley (SD)
Kai Yang   +4 more
doaj   +1 more source

The immunosuppressive agent mizoribine monophosphate is an inhibitor of the human RNA capping enzyme. [PDF]

open access: yesPLoS ONE, 2013
Mizoribine monophosphate (MZP) is a specific inhibitor of the cellular inosine-5'-monophosphate dehydrogenase (IMPDH), the enzyme catalyzing the rate-limiting step of de novo guanine nucleotide biosynthesis.
Frédéric Picard-Jean   +3 more
doaj   +1 more source

Inhibition and relaxation of sea urchin sperm flagella by vanadate [PDF]

open access: yes, 1980
Direct measurements of the stiffness (elastic bending resistance) of demembranated sera urchin sperm flagella were made in the presence of MgATP2- and vanadate.
Okuno, Makoto
core   +3 more sources

Nanomolar Inhibitors of Trypanosoma brucei RNA Triphosphatase

open access: yesmBio, 2016
Eukaryal taxa differ with respect to the structure and mechanism of the RNA triphosphatase (RTPase) component of the mRNA capping apparatus. Protozoa, fungi, and certain DNA viruses have a metal-dependent RTPase that belongs to the triphosphate tunnel ...
Paul Smith   +4 more
doaj   +1 more source

Hepatitis C virus pharmacogenomics in Latin American populations: implications in the era of direct-acting antivirals [PDF]

open access: yes, 2017
In recent years, great progress has been made in the field of new therapeutic options for hepatitis C virus (HCV) infection. The new direct-acting antiviral agents (DAAs) represent a great hope for millions of chronically infected individuals because ...
Caputo, Mariela   +4 more
core   +1 more source

Effects of cellular cholesterol loading on macrophage foam cell lysosome acidifications⃞

open access: yesJournal of Lipid Research, 2007
Macrophages incubated with mildly oxidized low density lipoprotein (OxLDL), aggregated low density lipoprotein (AggLDL), or cholesteryl ester-rich lipid dispersions (DISPs) accumulate cholesterol in lysosomes followed by an inhibition of lysosomal ...
Brian E. Cox   +3 more
doaj   +1 more source

Protective Role of Sarpogrelate in Combination with Bromocriptine and Cabergoline for Treatment of Diabetes in Alloxan-induced Diabetic Rats

open access: yesCurrent Therapeutic Research, 2021
: Background: Although dopamine D2 receptor agonists, bromocriptine and cabergoline, are notable medications in the treatment of Parkinsonism, hyperprolactinemia, and hyperglycemia, there is an identified relationship between the utilization of D2-like ...
Mohammed Fouad Shalaby, MD   +5 more
doaj   +1 more source

Molecular Characterization of Protease Activity in Serratia sp. Strain SCBI and Its Importance in Cytotoxicity and Virulence [PDF]

open access: yes, 2014
A newly recognized Serratia species, termed South African Caenorhabditis briggsae isolate (SCBI), is both a mutualist of the nematode Caenorhabditis briggsae KT0001 and a pathogen of lepidopteran insects. Serratia sp.
Petersen, Lauren M., Tisa, Louis S.
core   +2 more sources

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