Results 101 to 110 of about 616,340 (230)

Paracoccidioides spp.: the structural characterization of extracellular matrix, expression of glucan synthesis and associated genes and adhesins during biofilm formation

Frontiers in Microbiology
The genus Paracoccidioides includes Paracoccidioides lutzii and the Paracoccidioides brasiliensis complex, which comprises four phylogenetic species. A key feature distinguishing planktonic growth from biofilm is the presence of a 3D extracellular matrix
Lariane Teodoro Oliveira, Caroline Maria Marcos, Ana Karla Lima Freire Cabral, Ana Karla Lima Freire Cabral, Kaila Petronila Medina-Alarcón, Regina Helena Pires, Ana Marisa Fusco-Almeida, Maria José Soares Mendes-Giannini   +7 more
doaj   +1 more source

Avaliação do risco epidemiológico da carcinicultura catarinense usando como modelo a síndrome de taura e da doença da mancha branca [PDF]

, 2004
Dissertação (mestrado) - Universidade do Vale do Itajaí, Centro de Ciências Tecnológicas da Terra e do Mar. Programa de Mestrado Acadêmico em Ciência e Tecnologia Ambiental.A carcinicultura brasileira vem apresentando produtividade crescente nos últimos ...
Lenoch, Robert
core  

VDAC1 Upregulation Induces Hyperexcitability of Nociceptive Sensory Neurons Via Enhanced Mitochondrial Atp Efflux in Neuropathic Pain

Advanced Science, EarlyView.
The mechanism diagram of VDAC1 mediating neuronal excitability and neuropathic pain. Briefly, VDAC1 is expressed in DRG neurons and is upregulated following CCI‐induced neuropathic pain. This upregulation enhances ATP transport from mitochondria to the cytoplasm in sensory neurons, leading to increased neuronal excitability and pain behavior.
Fengrun Sun, Ning Yu, Liang Yu, Xiaofen Tian, Yujia Ma, Yikuan Xie, Tao Wang, Chao Ma   +7 more
wiley   +1 more source

Estudo e análise da ferramenta gerencial Eva® [PDF]

, 2004
TCC (Graduação) - Universidade Federal de Santa Catarina. Centro Socioeconômico. Curso de Ciências ContábeisEste trabalho tem por objetivo geral apresentar o EVA® (Valor Econômico Agregado) – uma ferramenta gerencial de cálculo de desempenho empresarial ...
Souza, Rafael Adalberto de
core  

改良的 Trizol 法提取小鼠皮肤 RNA 技术 [PDF]

, 2020
【目的】由于皮肤组织韧性强且存在大量RNA酶，采用经典Trizol法提取的RNA存在易降解质量低等不足。因此，本研究旨在通过改良的Trizol法实现高质量的皮肤RNA提取。【方法】采用不同处理方式（Tri：Trizol包埋；Pro：RNA样本保护液包埋；Cry：先冷冻液氮再冷冻-80℃冰箱；LNG：液氮研磨；Cut：采用剪刀剪碎组织）提取的小鼠正常皮肤RNA为实验组；脊髓组织作为参照组，并以咪喹莫特（IMQ）诱导的小鼠银屑病模型皮肤组织作为保真性验证组。我们采用紫外分光光度法、琼脂凝胶电泳法 ...
熊媖, 谈智, 刘先国, 张辉, 揭英桃, 唐源, 周利君, 林震嘉   +7 more
core  

TOLLIP Inhibits Psoriasis Progression via Suppressing PKM2‐Mediated Glycolysis in Keratinocytes

Advanced Science, EarlyView.
In this study, we identify TOLLIP as a critical regulator of psoriasis pathogenesis through its modulation of glycolytic metabolism. Our findings establish the TOLLIP‐PKM2‐glycolysis axis as a key mechanism linking metabolic reprogramming to psoriasis pathogenesis, and propose TOLLIP as a promising therapeutic target.
Xiuhuan Jiang, Guoying Miao, Na Shen, Qingxia Han, Xiaoru Han, Zichang Qiao, Kexin Feng, Zhuo Tan, Yaguang Wang, Xiuhua Liu, Chen Wu, Zhenzhen Yan   +11 more
wiley   +1 more source

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, 2017
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core   +1 more source

Sustainable Fabrication of Tailored Bone Substitutes: From High‐Throughput Scaffold Manufacturing, Scaled‐Up HMSC Expansion to Dynamic Cultivation in a Perfusion Bioreactor

Advanced Science, EarlyView.
ABSTRACT The demand for off‐the‐shelf biocompatible bone substitutes has driven the development of numerous independent in vitro technologies to generate products resembling physiological tissues. Due to technical challenges and overly simplified cultivation approaches/niches, the end‐products are often uniformly shaped and inferior to native bone ...
Franziska Braun, Anna Paříková, Sandra Rother, Martin Kantor, Salman Muhammad Ilyas, Ricardo Bernhardt, Pavel Ndjawa Yomi, Jaromír Havlica, Revathi Appali, Benjamin Kruppke, Poh Soo Lee   +10 more
wiley   +1 more source

Astrocytic LMP2 Coordinates NF‐κB and TGF‐β1/Smad3 Signaling to Drive Neuroinflammation after Cerebral Ischemia/Reperfusion

Advanced Science, EarlyView.
ABSTRACT Astrocyte reactivity critically shapes neuroinflammatory outcomes after ischemic stroke, yet the upstream regulators governing astrocyte state transitions remain incompletely defined. Here, we identify the immunoproteasome subunit low molecular weight protein 2 (LMP2) as an important modulator of astrocyte functional remodeling following ...
Yanguang Mao, Rulan Ma, Zejing Lin, Huiying Zhao, Yuexian Liu, Yonghe Su, Xu Zhang, Xingyong Chen   +7 more
wiley   +1 more source

Investigating gene expression profiles of whole blood and peripheral blood mononuclear cells using multiple collection and processing methods - Fig 3

, 2019
Two dimensional Sammon projection using the top 50% of most variable transcripts (25370) for whole blood (red) and PBMC (black). There is a clear distinction in clusters for PBMCs and whole blood sample processing as marked by a black tilted line.
Jesse Lynch (8098436), Allison Hoke (8098424), Leanne Detwiler (8098433), Michael Levangie (8098439), Marti Jett (19942), Bintu Sowe (8098430), Rasha Hammamieh (19941), Duncan Donohue (6475823), Seshamalini Srinivasan (7485002), Stacy Ann Miller (8098427), Aarti Gautam (307419)   +10 more
core   +1 more source