Results 121 to 130 of about 5,304 (178)
A critical role for Kalirin in NGF signaling through TrkA
Kalirin is a multidomain guanine nucleotide exchange factor (GEF) that activates Rho proteins, inducing cytoskeletal rearrangement in neurons. Although much is known about the effects of Kalirin on Rho GTPases and neuronal morphology, little is known ...
Schiller, Noraisha I. +8 more
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TrkA crosslinking mimics neuronal responses to nerve growth factor
TrkA, a tyrosine kinase receptor, is an essential component of the nerve growth factor (NGF) response pathway. The binding of NGF to the receptor induces receptor autophos-phorylation and activation of intracellular signaling pathways, resulting in ...
Douglas Clary +3 more
core
This paper presents the importance of the influence of past peoples, history and culture for the development of a location. The events and celebrations that took place in the distant past can be of great importance today not only for tourism but also for t he local population.
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Mechanisms of TrkA-induced cell death of neuroblastoma
Neuroblastoma is the most frequent solid extra-cranial tumor in children. Its clinical prognosis correlates with the expression pattern of members of the Trk neurotrophin receptor family, which includes TrkA, TrkB, and TrkC.
Lavoie, Jean-François
core
Functional interactions between the p75 neurotrophin receptor and TrkA
The p75NTR neurotrophin receptor has previously been shown to increase the responsiveness of TrkA to NGF, the preferred ligand of TrkA. We performed structure/function studies to determine the domains of p75 NTR involved in this functional interaction ...
Simoneau, Steve.
core
Općina Barban proteže se na gotovo 100 metara kvadratnih i graniči s mnogim drugim općinama. Barban je naselje u istoimenoj Općini, smješteno na povoljnom položaju, na brežuljku iznad doline rijeke Raše, nadomak Pule. Danas, Barban ima 221 stanovnika.
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Modeliranje trka osebnih vozil
Magistrsko delo obravnava gibanje vozil, udeleženih v prometnih nezgodah s pomočjo programskega orodja PC-Crash. Zaradi obširnosti problema je obravnava omejena na trk dveh osebnih vozil. V delu je uporabljena metoda togih teles, kjer deformabilnost upoštevam s korekcijskimi faktorji, impulzna in energijska metoda.
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NGF binds to two receptors, p75NTR and TrkA. The endosomal trafficking of receptors is of emerging importance for the understanding of their signaling. We compared the endocytic trafficking of the two NGF receptors in PC12 cells. Both p75NTR and TrkA were internalized in response to NGF and colocalized with early endosomes.
Saxena S +7 more
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