Results 101 to 110 of about 27,805 (268)

Resident memory T cell development is gradual and shows AP-1 gene expression in mature cells

JCI Insight
Tissue-resident memory T (TRM) cells play a central role in immune responses across all barrier tissues after infection. However, the mechanisms that drive TRM differentiation and priming for their recall effector function remains unclear. In this study,
Neal P. Smith, Yu Yan, Youdong Pan, Jason B. Williams, Kasidet Manakongtreecheep, Shishir M. Pant, Jingxia Zhao, Tian Tian, Timothy Pan, Claire Stingley, Kevin Wu, Jiang Zhang, Alexander L. Kley, Peter K. Sorger, Alexandra-Chloé Villani, Thomas S. Kupper   +15 more
doaj   +1 more source

Nomenclature on Immune‐Mediated Drug Reactions: An EAACI Position Paper

Allergy, EarlyView.
ABSTRACT Over the past several decades, there have been significant advances in our understanding of both immunological and pharmacological mechanisms of adverse drug reactions (ADRs). Immune‐mediated drug reactions (IMDRs) represent a small proportion of ADRs and are caused by a pathological activation of the immune system or inflammatory pathways ...
Maria J. Torres, Cristobalina Mayorga, Elizabeth J. Phillips, Adriana Ariza, Annick Barbaud, Patrizia Bonadonna, Mariana Castells, Gülfem Çelik, Knut Brockow, Lene H. Garvey, Inmaculada Doña, Jean‐Christoph Caubet, Francesca Mori, Jason Trubiano, Giorgia Marta, Antonino Romano, Ingrid Terreehorst, Asli Gelincik, Philip H. Li, Vito Sabato   +19 more
wiley   +1 more source

Crystalline silica-induced recruitment and immuno-imbalance of CD4+ tissue resident memory T cells promote silicosis progression

Communications Biology
Occupational crystalline silica (CS) particle exposure leads to silicosis. The burden of CS-associated disease remains high, and treatment options are limited due to vague mechanisms.
Yichuan You, Xiulin Wu, Haoyang Yuan, Yangyang He, Yinghui Chen, Sisi Wang, Hui Min, Jie Chen, Chao Li   +8 more
doaj   +1 more source

Correction to “Micromagnetic models of pseudo-single domain grains of magnetite near the Verwey Transition” [PDF]

, 1999
Domain structures of small pseudo-single domain (PSD) magnetite near the Verwey transition (Tυ) at ≈120 K were modeled using an unconstrained three-dimensional micromagnetic algorithm.
A. R. Muxworthy, W. Williams, Muxworthy, A. R., Williams, Wyn; id_orcid   +3 more
core   +1 more source

BHLHE40 Orchestrates Effector Tissue‐Resident Memory CD8+ T Cells and Limits Long‐Term Survival of Kidney Graft

Advanced Science
Tissue‐resident memory T cells (TRM), which function against tumors, infections, and non‐self antigens in organ transplantation, exhibit both effector and memory functionality. However, the homeostasis and differentiation of TRM is not clear.
Junbo Li, Bo Yang, Tianhui Pan, Xi Zhou, Zhibo Ma, Du Tang, Bowen Xie, Jing Liu, Zhishui Chen, Peixiang Lan   +9 more
doaj   +1 more source

Flexural Behavior of Fire-Damaged Prefabricated RC Hollow Slabs Strengthened with CFRP versus TRM

, 2020
In this paper, carbon fiber reinforced polymer (CFRP) and textile reinforced mortar (TRM) strengthening techniques were proposed to retrofit and strengthen fire-damaged prefabricated concrete hollow slabs. A total of six slabs, from an actual multi-story
Jitong Jiang, Zheng-Ang Sui, Kun Dong, Shutong Yang, Kexu Hu   +4 more
core   +1 more source

A Proposal to Achieve Sustainable Development Goals in the Luxury Fashion Industry

Business Ethics, the Environment &Responsibility, EarlyView.
ABSTRACT The luxury industry stands at a crossroads between tradition and sustainability. The objective of this paper is to analyse the relationship and effects of the luxury fashion industry on the Sustainable Development Goals (SDGs) and identify opportunities to improve its management.
Alicia Parro‐Ruiz, María‐Sonia Medina‐Salgado, Marta Ortiz‐de‐Urbina‐Criado, María Torrejón‐Ramos   +3 more
wiley   +1 more source

Incidental Findings From Treatment Response Monitoring in Oncological Care: Ethical Reflections

Bioethics, EarlyView.
ABSTRACT The question of how to handle incidental findings in medicine has attracted a lot of attention in the bioethics literature. The most widely discussed examples come from genetics (e.g., next generation sequencing) and medical imaging (e.g., neuroimaging).
Jasper Debrabander, Stefano Fanti, Elisabetta Lalumera   +2 more
wiley   +1 more source

trm-scatac

Final fragment files for TRM scATAC-seq mouse data ...
Pat Yan, Caleb Lareau
core  

Updates in acute graft‐versus‐host disease: From novel pathogenic mechanisms to emerging therapeutic targets

British Journal of Haematology, EarlyView.
The graphical abstract provides a view on selected aspects of the pathogenesis, risk stratification and treatment of acute GVHD. Summary Acute graft‐versus‐host disease (aGVHD) remains a major complication following allogeneic haematopoietic stem cell transplantation (allo‐HSCT), representing a leading cause of non‐relapse mortality (NRM) and ...
Hazim Khatib, Robert Zeiser
wiley   +1 more source