Results 81 to 90 of about 27,805 (268)

Artificial Intelligence for Identifying Tumor‐Reactive CD8+ T Cells: Biological Principles, Computational Advances, and Future Directions

open access: yesMed Research, EarlyView.
This review details a three‐stage paradigm shift for tumor‐reactive CD8+ T‐cell identification: decoding transcriptomic states, deciphering clonal functional efficacy, and molecular‐level therapeutic TCR design. Addressing translational hurdles and generative AI “scientific blind spots”—such as missing catch bonds—we present a visionary roadmap.
Chao Yang   +4 more
wiley   +1 more source

Χρήση TRM για ενεργειακή και σεισμική αναβάθμιση υφιστάμενων κτιρίων

open access: yes, 2019
Στην παρούσα μελέτη παρουσιάζεται ο ορισμός του TRM και οι μηχανικές του ιδιότητες. Το TRM είναι ένα σύνθετο υλικό αφού αποτελείτε από κονίαμα το οποίο ενισχύεται με υφασμάτινες ίνες υψηλής αντοχής άνθρακα, βασάλτη, ή γυαλιού.
Δημητρίου, Ραφαέλλας
core  

Armed and Ready: Transcriptional Regulation of Tissue-Resident Memory CD8 T Cells

open access: yesFrontiers in Immunology, 2018
A fundamental benefit of immunological memory is the ability to respond in an enhanced manner upon secondary encounter with the same pathogen. Tissue-resident memory CD8 T (TRM) cells contribute to improved protection against reinfection through the ...
Felix M. Behr   +6 more
doaj   +1 more source

A FE Model for TRM Reinforced Masonry Walls with Interface Effects

open access: yes, 2019
International audienceWe report on experimental and numerical investigations of textile reinforced mortar (TRM) strengthening systems, an innovative solution for reinforcing historical masonry structures. The experimental campaign presented in this paper
Aprile, Alessandra   +14 more
core   +1 more source

Flax-TRM Composite Systems for Strengthening of Masonry

open access: yes, 2021
This book is intended to raise awareness about the use of sustainable Textile-Reinforced Mortar (TRM) composite systems, including plant fibers, for civil engineering applications. It presents a comprehensive characterization of the mechanical properties
Giuseppe Ferrara
core   +1 more source

Cortical Cholinergic Pathway Degeneration Reflects Cognitive Impairment and Dementia in Parkinson's Disease

open access: yesMovement Disorders, EarlyView.
Abstract Background Cognitive impairment is a prevalent and debilitating feature of Parkinson's disease (PD). Increasing evidence from postmortem and in vivo positron emission tomography imaging studies supports cholinergic dysfunction in PD. There is, however, little evidence regarding the influence of the structural integrity of cortical cholinergic ...
Nicola M. Slater   +13 more
wiley   +1 more source

An integrated forest‐to‐market approach to promote lesser‐known timber species (LKTS) in a domestic timber market in the Congo Basin

open access: yesPLANTS, PEOPLE, PLANET, EarlyView.
In the Congo Basin, domestic timber markets account for ~40% of timber consumption, yet demand is concentrated on a few high‐value species also sought after on international markets, raising concerns about their long‐term availability. We combine market, wood, and forest data to assess the potential of lesser‐known timber species (LKTS) to support a ...
Mbusa Wasukundi   +19 more
wiley   +1 more source

Metabolic Reprogramming and Longevity of Tissue-Resident Memory T Cells

open access: yesFrontiers in Immunology, 2018
Tissue-resident memory T cells (TRM) persist in peripheral tissues for long periods of time in the absence of antigenic stimulation. Upon re-encounter with cognate antigen, TRM trigger an immediate immune response at the local tissue microenvironment and
Youdong Pan, Thomas S. Kupper
doaj   +1 more source

Hypoxia acts as an environmental cue for the human tissue-resident memory T cell differentiation program

open access: yesJCI Insight, 2021
Tissue-resident memory T cells (TRM) provide frontline defense against infectious diseases and contribute to antitumor immunity; however, aside from the necessity of TGF-β, knowledge regarding TRM-inductive cues remains incomplete, particularly for human
Farah Hasan   +4 more
doaj   +1 more source

Home - About - Disclaimer - Privacy