Results 211 to 220 of about 4,753,527 (236)

Indiscriminate nature of lung resident CD8+ TRM cells reactivation and their varied reactivation profiles

The Journal of Immunology, 2019
Abstract CD8+ tissue resident memory (TRM) cells are poised at the portals of infection and confer immediate protection upon reinfection. Despite the critical role of CD8+ TRM cells in long-term protective immunity, the precise mechanics governing their reactivation in-situ are unclear.
Jun Siong Low, Caro Amezcua, Esen Sefik, Christian C D Harman, Ruaidhri Jackson, Xiaodong Jiang, Joseph Barrack Kelly, Linda S Cauley, Richard A Flavell, Susan Kaech   +9 more
openaire   +1 more source

Immune pressure against ovarian cancer depends on antigen-specific TRM T cells

The Journal of Immunology, 2019
Abstract Conventional memory T cells classically include central memory T (TCM) cells, residing in lymphoid organs, and effector memory T (TEM) cells, circulating through various tissues. Recently, a novel population of memory T cells has gained interest, namely tissue resident memory T (TRM) cells, which persist in tissues and do not ...
Carmen Maria Anadon Galindo, Jairo Perez Sanz, Subir Biswas, Kyle K Payne, Xiaoqing Yu, Tara Lee Costich, Ricardo Chaurio Gonzalez, Jose R Conejo-Garcia   +7 more
openaire   +1 more source

Alt-RNAtive vaccines elicit anti-malarial TRM cells

Nature Immunology, 2023
Mariah Hassert, John T. Harty
openaire   +2 more sources

The roles of tissue-resident memory T cells (TRMs) in diseases and vaccine development: A comprehensive review

Vaccine
Tissue-resident memory T cells (TRMs) are integral to localized immune defense, characterized by their capacity for long-term tissue residency and rapid effector responses in infectious diseases. Beyond their established roles in antimicrobial immunity, TRMs exhibit unique therapeutic potential in tumor immunology and vaccine design.
Hongyu, Wei, Yunfeng, Wang, Shichun, Jiang, Xiaoli, Zhang, Jinyong, Zhang   +4 more
openaire   +2 more sources

Memory Lymphocyte Clusters in Genital Immunity: Role of Tissue-Resident Memory T Cells (TRM)

2020
Development of front-line defenses in genital tissues is important to inhibit viral/bacterial replication and to eliminate sexually transmitted diseases. In this chapter, we discuss the cellular composition, location, and function of memory lymphocyte clusters deployed in mucosal tissues and compare them with those in secondary lymphoid organs and ...
openaire   +2 more sources

Tissue resident memory T cells (TRM)

The Biomedical & Life Sciences Collection, 2022
openaire   +1 more source

Stem Cell Epigenetics in Medical Therapy

Medical Epigenetics, 2021
Peng Jin, Liqi Shu
exaly  

Maintaining TRM cells

Nature Immunology, 2017
openaire   +2 more sources

Skin CD4+ Trm Cells Distinguish Acute Cutaneous Lupus Erythematosus From Localized Discoid Lupus Erythematosus/Subacute Cutaneous Lupus Erythematosus and Other Skin Diseases

Journal of Autoimmunity, 2022
Qianjin Lu, Haijing Wu, Wei Liao
exaly  

Insights Into Phenotypic and Functional CD8+ TRM Heterogeneity

Immunological Reviews, 2023
Ananda W Goldrath, Maximilian Heeg
exaly