Results 21 to 30 of about 36,147 (195)
tRNA-derived small RNAs (tsRNAs) in cardiovascular diseases: biogenesis, functions, and therapeutic targets [PDF]
Frontiers in Cardiovascular MedicineXie C +6 more
exaly +2 more sources
Classification, function, and advances in tsRNA in non-neoplastic diseases
Cell Death and Disease, 2023 tRNA-derived small RNAs (tsRNAs) are non-coding small RNAs produced by specific endonucleases following the processing and splicing of precursor or mature tRNAs upon starvation, oxidative stress, hypoxia, and other adverse conditions.
Liou Zhang, Jie Liu, Yang Hou
doaj +1 more source
Unveiling the role of tRNA-derived small RNAs in MAPK signaling pathway: implications for cancer and beyond [PDF]
Frontiers in GeneticsShiwei Duan, Qurui Wang, Duan Shiwei
exaly +2 more sources
The epitranscriptome of small non-coding RNAs
Non-coding RNA Research, 2021 Small non-coding RNAs are short RNA molecules and involved in many biological processes, including cell proliferation and differentiation, immune response, cell death, epigenetic regulation, metabolic control.
Xiaoyu Li, Jinying Peng, Chengqi Yi
doaj +1 more source
tRNA Fragments Populations Analysis in Mutants Affecting tRNAs Processing and tRNA Methylation
Frontiers in Genetics, 2020 tRNA fragments (tRFs) are a class of small non-coding RNAs (sncRNAs) derived from tRNAs. tRFs are highly abundant in many cell types including stem cells and cancer cells, and are found in all domains of life.
Anahi Molla-Herman +5 more
doaj +1 more source
Frontiers in Endocrinology, 2021 Most of the sequences in the human genome do not code for proteins but generate thousands of non-coding RNAs (ncRNAs) with regulatory functions. High-throughput sequencing technologies and bioinformatic tools significantly expanded our knowledge about ...
Cécile Jacovetti +3 more
doaj +1 more source
Memorias do Instituto Oswaldo Cruz, 2012 Small non-coding RNAs derived from transfer RNAs have been identified as a broadly conserved prokaryotic and eukaryotic response to stress. Their presence coincides with changes in developmental state associated with gene expression regulation.
Larissa Reifur +8 more
doaj +1 more source
Cell Reports, 2013 Transfer RNA (tRNA) fragmentation in response to stress conditions has been described in many organisms. tRNA fragments have been found in association with small interfering RNA (siRNA) components, but the biological role of these interactions remains ...
Zeljko Durdevic +4 more
doaj +1 more source
METTL1 promotes tumorigenesis through tRNA-derived fragment biogenesis in prostate cancer
Molecular Cancer, 2023 Newly growing evidence highlights the essential role that epitranscriptomic marks play in the development of many cancers; however, little is known about the role and implications of altered epitranscriptome deposition in prostate cancer.
Raquel García-Vílchez +36 more
doaj +1 more source
Mapping the small RNA content of simian immunodeficiency virions (SIV).
PLoS ONE, 2013 Recent evidence indicates that regulatory small non-coding RNAs are not only components of eukaryotic cells and vesicles, but also reside within a number of different viruses including retroviral particles.
Markus Brameier +5 more
doaj +1 more source