Results 181 to 190 of about 4,159 (191)

Nanoarchaeum equitans creates functional tRNAs from separate genes for their 5′- and 3′-halves

Nature, 2005
Analysis of the genome sequence of the small hyperthermophilic archaeal parasite Nanoarchaeum equitans has not revealed genes encoding the glutamate, histidine, tryptophan and initiator methionine transfer RNA species. Here we develop a computational approach to genome analysis that searches for widely separated genes encoding tRNA halves that, on the ...
Lennart, Randau, Richard, Münch, Michael J, Hohn, Dieter, Jahn, Dieter, Söll   +4 more
openaire   +2 more sources

Identification of aberrant expression of tRNA halves in renal cell carcinoma

2016
Question: Small non-coding RNAs (sncRNA; < 200nt) modify gene expression and thereby regulate various cellular processes. sncRNA expression profiles are changing during carcinogenesis. We therefore performed Next Generation Sequencing to identify clear cell renal cell carcinoma (ccRCC) specific[for full text, please go to the a.m. URL]
Ellinger, J, Nientiedt, M, Deng, M, Schmidt, D, Kristiansen, G, Perner, S, Müller, SC   +6 more
openaire   +2 more sources

Developmentally-controlled generation of tRNA halves facilitates translational repression during sexual reproduction

Abstract The role of transfer RNAs (tRNAs) as mediators between the genetic code and protein synthesis is well established. In parallel, tRNAs can generate different types of functional small RNAs (sRNAs) that accumulate during stress and certain developmental processes across diverse organisms.
Vasti Thamara Juarez-Gonzalez, Joan Marquez-Molins, Jinping Cheng, Juan Luis Reig-Valiente, Konstantin Kutashev, Stefanie Rosa, German Martinez   +6 more
openaire   +1 more source

5’-tRNA-halves: circulating syncytiotrophoblast RNA signals in early-onset preeclampsia

Placenta, 2021
William Cooke, Peiyong Jiang, Lu Ji, Gabriel Jones, Wei Zhang, Neva Kandzija, Ana Sofia Cerdeira, Dennis Lo, Christopher Redman, Manu Vatish   +9 more
openaire   +1 more source

Halves and fragments derived of tRNAs in Escherichia coli are selectively associated with 30S ribosomal subunits and in the cytosol

Abstract The generation of tRNA halves and fragments (tsRNAs) has been associated with stressful growth conditions in eukaryotes, but reports on tsRNAs in bacteria are scarce. Here, we demonstrate that the presence of tsRNAs in Escherichia coli depends on active translation, and that they are found in the 30S ribosomal subunit and the ...
Eva Jacinto-Loeza, Augusto Uc-Mass, Gabriel Guarneros   +2 more
openaire   +1 more source

Ligation of endogenous tRNA 3′ half molecules to their corresponding 5′ halves via 2′-phosphomonoester,3′,5′-phosphodiester bonds in extracts of Chlamydomonas 1

EMBO Journal, 1983
Witold Filipowicz, Hans J Gross
exaly  

Circular dichroism of yeast valine tRNA and its halves.

Molecular biology, 1973
G B, Zavil'gel'skii, A D, Mirzabekov, A I, Poletaev, A A, Baev   +3 more
openaire   +1 more source

Re: Sex Hormone-Dependent tRNA Halves Enhance Cell Proliferation in Breast and Prostate Cancers

Journal of Urology, 2016
openaire   +2 more sources

The heteromeric Nanoarchaeum equitans splicing endonuclease cleaves noncanonical bulge-helix-bulge motifs of joined tRNA halves

Proceedings of the National Academy of Sciences of the United States of America, 2005
Lennart Randau, Dieter Soll, Jing Yuan   +2 more
exaly  

The ‘recently’ split transfer RNA genes may be close to merging the two halves of the tRNA rather than having just separated them

Journal of Theoretical Biology, 2012
Massimo Di Giulio
exaly