Results 11 to 20 of about 11,423 (138)

Mesenchymal Stem Cells in Embryo-Maternal Communication under Healthy Conditions or Viral Infections: Lessons from a Bovine Model

Cells, 2022
Bovine mesenchymal stem cells are a relevant cell population found in the maternal reproductive tract that exhibits the immunomodulation capacity required to prevent embryo rejection.
Alexandra Calle, Miguel Ángel Ramírez
doaj   +1 more source

Essential roles of HDAC1 and 2 in lineage development and genome-wide DNA methylation during mouse preimplantation development

Epigenetics, 2020
Epigenetic modifications, including DNA methylation and histone modifications, are reprogrammed considerably following fertilization during mammalian early embryonic development.
Panpan Zhao, Huanan Wang, Han Wang, Yanna Dang, Lei Luo, Shuang Li, Yan Shi, Lefeng Wang, Shaohua Wang, Jesse Mager, Kun Zhang   +10 more
doaj   +1 more source

Trophectoderm cell failure leads to peri-implantation lethality in Trpm7-deficient mouse embryos

Cell Reports, 2021
Summary: Early embryogenesis depends on proper control of intracellular homeostasis of ions including Ca2+ and Mg2+. Deletion of the Ca2+ and Mg2+ conducting the TRPM7 channel is embryonically lethal in mice but leaves compaction, blastomere polarization,
Aline Schütz, Christin Richter, Petra Weissgerber, Volodymyr Tsvilovskyy, Michael Hesse, Roger Ottenheijm, Frank Zimmermann, Stefanie Buchholz, Rebekka Medert, Sascha Dlugosz, Vladimir Kuryshev, Vladimir Benes, Veit Flockerzi, Bernd K. Fleischmann, Adolfo Cavalié, Marc Freichel   +15 more
doaj   +1 more source

Euploid Day-5 Blastocysts Versus Euploid Day-6 Blastocysts — Will the Reproductive Outcomes Differ? An Observational Study

Fertility & Reproduction, 2021
Background and objective: Day-5 blastocyst embryos are usually chosen for assisted reproductive therapy. We compared the reproductive outcomes of the euploid blastocysts developed on Day 5 versus Day 6.
Durga Gedela Rao, Krishna Chaitanya Mantravadi, Vijay Kumar Sharanappa   +2 more
doaj   +1 more source

The Human Early Maternal–Embryonic Interactome

Reproductive Medicine, 2023
Background: Single cell transcriptomics offers an avenue for predicting, with improved accuracy, the gene networks that are involved in the establishment of the first direct cell–cell interactions between the blastocyst and the maternal luminal ...
Adam Stevens, Taqua Khashkhusha, Megan Sharps, Terence Garner, Peter T. Ruane, John D. Aplin   +5 more
doaj   +1 more source

Tetraploid embryo aggregation produces high-quality blastocysts with an increased trophectoderm in pigs

Frontiers in Cell and Developmental Biology, 2023
Tetraploid complementation is an ideal method for demonstrating the differentiation potential of pluripotent stem cells. In this study, we selected the most efficient tetraploid production method for porcine embryos and investigated whether tetraploid ...
Joohyeong Lee, Lian Cai, Lian Cai, Lian Cai, Mirae Kim, Mirae Kim, Hyerin Choi, Hyerin Choi, Dongjin Oh, Dongjin Oh, Ali Jawad, Ali Jawad, Eunsong Lee, Sang-Hwan Hyun, Sang-Hwan Hyun, Sang-Hwan Hyun   +15 more
doaj   +1 more source

Which is the safer method for trophectoderm biopsy in mouse blastocyst, mechanical or laser?

Clinical and Experimental Obstetrics & Gynecology, 2020
Introduction: This study was conducted to compare hatching rates after assisted hatching, re-expansion rates after trophectoderm biopsy, and survival rates after cryopreservation using different methods of assisted hatching and biopsy in mouse embryo ...
M.S. Jo, H.J. Lee, Y.J. Lee, S.C. Kim, J.K. Joo, K.S. Lee   +5 more
doaj   +1 more source

Transitions in cell potency during early mouse development are driven by Notch

eLife, 2019
The Notch signalling pathway plays fundamental roles in diverse developmental processes in metazoans, where it is important in driving cell fate and directing differentiation of various cell types.
Sergio Menchero, Isabel Rollan, Antonio Lopez-Izquierdo, Maria Jose Andreu, Julio Sainz de Aja, Minjung Kang, Javier Adan, Rui Benedito, Teresa Rayon, Anna-Katerina Hadjantonakis, Miguel Manzanares   +10 more
doaj   +1 more source

BMP-treated human embryonic stem cells transcriptionally resemble amnion cells in the monkey embryo

Biology Open, 2021
Human embryonic stem cells (hESCs) possess an immense potential to generate clinically relevant cell types and unveil mechanisms underlying early human development.
Sapna Chhabra, Aryeh Warmflash
doaj   +1 more source

A developmental insurance policy

eLife, 2017
Why does a totipotent state linger within the inner cell mass of mouse embryos?
Nestor Saiz, Anna-Katerina Hadjantonakis
doaj   +1 more source