Results 31 to 40 of about 15,306 (209)
Transitions in cell potency during early mouse development are driven by Notch
The Notch signalling pathway plays fundamental roles in diverse developmental processes in metazoans, where it is important in driving cell fate and directing differentiation of various cell types.
Sergio Menchero +10 more
doaj +1 more source
Morphometric assessment of blastocysts: relationship with the ongoing pregnancy rate
Objective: To explore a morphometric grading system for blastocysts that is associated with ongoing pregnancy. Design: Cross-sectional study. Setting: None.
Hiroki Utsuno, Ph.D. +9 more
doaj +1 more source
A developmental insurance policy
Why does a totipotent state linger within the inner cell mass of mouse embryos?
Nestor Saiz, Anna-Katerina Hadjantonakis
doaj +1 more source
Derivation of trophoblast stem cells from naïve human pluripotent stem cells
Naïve human pluripotent stem cells (hPSCs) provide a unique experimental platform of cell fate decisions during pre-implantation development, but their lineage potential remains incompletely characterized.
Chen Dong +13 more
doaj +1 more source
Purpose This study investigated the consistency between results of preimplantation genetic testing for aneuploidy performed on trophectoderm (TE) cells and remaining blastocyst cells.
Harunori Takahashi +13 more
doaj +1 more source
The first lineage choice made in human embryo development separates trophectoderm from the inner cell mass, which proceeds to form the pluripotent epiblast and primitive endoderm. Trophectoderm on the other hand gives rise to the placenta.
Schell, J +6 more
core +1 more source
The first cell fate choice of the preimplantation embryo generates the extraembryonic trophoblast and embryonic epiblast lineages. Embryonic stem cells (ESCs) and trophoblast stem cells (TSCs) can be utilized to investigate molecular mechanisms of this ...
Ursula Nosi +3 more
doaj +1 more source
BMP-treated human embryonic stem cells transcriptionally resemble amnion cells in the monkey embryo
Human embryonic stem cells (hESCs) possess an immense potential to generate clinically relevant cell types and unveil mechanisms underlying early human development.
Sapna Chhabra, Aryeh Warmflash
doaj +1 more source
Contribution of JAM-1 to epithelial differentiation and tight-junction biogenesis in the mouse preimplantation embryo [PDF]
We have investigated the contribution of the tight junction (TJ) transmembrane protein junction-adhesion-molecule 1 (JAM-1) to trophectoderm epithelial differentiation in the mouse embryo.
Fay C. Thomas +11 more
core +1 more source
Low reproductive efficiency of high-yielding dairy cows is a worldwide challenge, among which the high mortality rate of early embryos is one of the main reasons.
WU Xiaotong +4 more
doaj +1 more source

