Results 41 to 50 of about 87,349 (342)
eLife, 2019 Studies suggest that placental nutrient supply adapts according to fetal demands. However, signaling events underlying placental adaptations remain unknown.
Jorge López-Tello +12 more
doaj +1 more source
RBM10 Regulates Embryonic Trophoblast Injury via Endoplasmic Reticulum Stress
Clinical and Experimental Obstetrics & Gynecology, 2022 Background: Previous studies shown that RNA binding motif proteins (RBM) participate in regulating various physiological processes such as cell autophagy, proliferation, and apoptosis, and are abnormally highly expressed in placental trophoblast cells ...
Xiao Chen +4 more
doaj +1 more source
Frontiers in Immunology, 2021 The immune tolerance microenvironment is crucial for the establishment and maintenance of pregnancy at the maternal-fetal interface. The maternal-fetal interface is a complex system containing various cells, including lymphocytes, decidual stromal cells,
Jinli Ding +5 more
semanticscholar +1 more source
Ecotoxicology and Environmental Safety, 2022 Human trophoblast cell apoptosis may induce miscarriage. Trophoblast cells are sensitive to environmental BaP-7,8-dihydrodiol-9,10-epoxide (BPDE). However, how BPDE induces human trophoblast cell apoptosis is still largely elusive.
Xinying Huang +8 more
doaj +1 more source
Decreased USP2a Expression Inhibits Trophoblast Invasion and Associates With Recurrent Miscarriage
Frontiers in Immunology, 2021 An appropriate development of the placenta consisting of trophoblast cell migration, invasion, proliferation, and apoptosis, is essential to establishing and maintaining a successful pregnancy.
Jiayu Wang +6 more
semanticscholar +1 more source
Proceedings of the National Academy of Sciences of the United States of America, 2020 Significance Defects in development and differentiation of the placenta are associated with various pregnancy disorders such as miscarriage, stillbirth, preeclampsia, and intrauterine growth restriction.
G. Meinhardt +10 more
semanticscholar +1 more source
A Critical Role of TET1/2 Proteins in Cell-Cycle Progression of Trophoblast Stem Cells
Stem Cell Reports, 2018 Summary: The ten-eleven translocation (TET) proteins are well known for their role in maintaining naive pluripotency of embryonic stem cells. Here, we demonstrate that, jointly, TET1 and TET2 also safeguard the self-renewal potential of trophoblast stem ...
Stephanie Chrysanthou +7 more
doaj +1 more source
Acta Biochimica et Biophysica Sinica, 2023 Accumulating evidence has shown that the apoptosis of trophoblast cells plays an important role in the pathogenesis of preeclampsia, and an intricate interplay between DNA methylation and polycomb group (PcG) protein-mediated gene silencing has been ...
Xie Lin +13 more
doaj +1 more source
Expression of CD82 in human trophoblast and its role in trophoblast invasion. [PDF]
PLoS ONE, 2012 BACKGROUND: Well-controlled trophoblast invasion at maternal-fetal interface is a critical event for the normal development of placenta. CD82 is a member of transmembrane 4 superfamily, which showed important role in inhibiting tumor cell invasion and ...
Qian Zhang +4 more
doaj +1 more source
Brazilian Journal of Medical and Biological Research, 2023 Inadequate invasion and excessive apoptosis of trophoblast cells are associated with the development of preeclampsia. Vitamin D deficiency in pregnant women may lead to an increased risk of preeclampsia.
Xiaoyu Tian +5 more
doaj +1 more source