Results 41 to 50 of about 109,495 (390)

The Trophoblast: A Rejoinder [PDF]

Science, 1904
n ...
openaire   +3 more sources

Human amniotic fluid glycoproteins expressing sialyl Lewis carbohydrate antigens stimulate progesterone production in human trophoblasts in vitro [PDF]

, 2004
Background: Progesterone is thought to mediate immune modulator effects by regulating uterine responsiveness. The aim of the study was to clarify the effect of transferrin and glycodelin A (former name PP14) as sialyl Lewis X-expressing glycoproteins on ...
Annett Streu, Beer AE, Crosignani PG, Dagmar-Ulrike Richter, Heiner Müller, Ioannis Mylonas, Jeschke U, Julkunen M, Julkunen M, Julkunen M, Klaus Friese, Kliman HJ, Loh TT, Mandler RN, Martinovic S, Mylonas I, Okamoto N, Seki H, Shanker YG, Siiteri PK, Starreveld JS, Udo Jeschke, Vanderpuye OA, Volker Briese, Zelewski L   +24 more
core   +1 more source

Pivotal role of the transcriptional co-activator YAP in trophoblast stemness of the developing human placenta

Proceedings of the National Academy of Sciences of the United States of America, 2020
Significance Defects in development and differentiation of the placenta are associated with various pregnancy disorders such as miscarriage, stillbirth, preeclampsia, and intrauterine growth restriction.
G. Meinhardt, S. Haider, V. Kunihs, L. Saleh, J. Pollheimer, C. Fiala, Szabolcs Hetey, Zsofia Feher, A. Szilágyi, N. Than, M. Knöfler   +10 more
semanticscholar   +1 more source

Regulation of Placental Development and Its Impact on Fetal Growth—New Insights From Mouse Models

Frontiers in Endocrinology, 2018
The placenta is the chief regulator of nutrient supply to the growing embryo during gestation. As such, adequate placental function is instrumental for developmental progression throughout intrauterine development.
Laura Woods, Laura Woods, Vicente Perez-Garcia, Vicente Perez-Garcia, Myriam Hemberger, Myriam Hemberger   +5 more
doaj   +1 more source

N-glycans of human amniotic fluid transferrin stimulate progesterone production in human first trimester trophoblast cells in vitro [PDF]

, 2004
Aims: During pregnancy, the placenta produces a variety of steroid hormones and proteins. Several of these substances have been shown to exert immunomodulatory effects.
Briese, V., Friese, K., Gundel, G., Jeschke, U., Mylonas, I., Müller, H., Richter, D.-U., Streu, A., Unverzagt, C.   +8 more
core   +1 more source

Capturing Human Trophoblast Development with Naïve Pluripotent Stem Cells In Vitro

bioRxiv, 2020
Trophoblast are extra-embryonic cells that are essential to maintain pregnancy. Human trophoblasts arise from the morula as trophectoderm (TE), which, after implantation, differentiates into cytotrophoblast (CT), syncytiotrophoblast (ST), and ...
Shingo Io, Mio Kabata, Yoshiki Iemura, Katsunori Semi, N. Morone, I. Okamoto, Tomonori Nakamura, Yoji Kojima, C. Iwatani, H. Tsuchiya, Belinda Kaswandy, E. Kondoh, M. Saitou, Takuya Yamamoto, M. Mandai, Yasuhiro Takashima   +15 more
semanticscholar   +1 more source

Fetal and trophoblast PI3K p110α have distinct roles in regulating resource supply to the growing fetus in mice

eLife, 2019
Studies suggest that placental nutrient supply adapts according to fetal demands. However, signaling events underlying placental adaptations remain unknown.
Jorge López-Tello, Vicente Pérez-García, Jaspreet Khaira, Laura C Kusinski, Wendy N Cooper, Adam Andreani, Imogen Grant, Edurne Fernández de Liger, Brian YH Lam, Myriam Hemberger, Ionel Sandovici, Miguel Constancia, Amanda N Sferruzzi-Perri   +12 more
doaj   +1 more source

Effects of Circulating and Local Uteroplacental Angiotensin II in Rat Pregnancy. [PDF]

, 2010
The renin-angiotensin (Ang) system is important during placental development. Dysregulation of the renin-Ang system is important in preeclampsia (PE). Female rats transgenic for the human angiotensinogen gene crossed with males transgenic for the human ...
Brosnihan, KB, Cartwright, JE, Dechend, R, Geusens, N, Hering, L, Herse, F, Huppertz, B, Luft, FC, Muller, DN, Pijnenborg, R, Staff, AC, Verlohren, S, Wenzel, K   +12 more
core   +1 more source

Cooperation between NSPc1 and DNA methylation represses HOXA11 expression and promotes apoptosis of trophoblast cells during preeclampsia

Acta Biochimica et Biophysica Sinica, 2023
Accumulating evidence has shown that the apoptosis of trophoblast cells plays an important role in the pathogenesis of preeclampsia, and an intricate interplay between DNA methylation and polycomb group (PcG) protein-mediated gene silencing has been ...
Xie Lin, Ding Ning, Sheng Siqi, Zhang Honghong, Yin He, Gao Lina, Zhang Hui, Ma Shengchao, Yang Anning, Li Guizhong, Jiao Yun, Shi Qing, Jiang Yideng, Zhang Huiping   +13 more
doaj   +1 more source

Caffeine Inhibits EGF-Stimulated Trophoblast Cell Motility through the Inhibition of mTORC2 and Akt. [PDF]

, 2012
Impaired trophoblast invasion is associated with pregnancy disorders such as early pregnancy loss and preeclampsia. There is evidence to suggest that the consumption of caffeine during pregnancy may increase the risk of pregnancy loss; however, little is
Alison E. Wallace, Bauer, Beavo, Biadasiewicz, Boulbes, Brent, Brooke Lumicisi, Brosens, Burton, CARE Study Group, Cartwright, Cartwright, Cartwright, Chui, Di Fiore, Fabro, Foukas, Goldstein, Gude, Guy S. Whitley, Hofmann, Isobelle Grant, Jang, Judith E. Cartwright, Julien, LaMarca, LaMarca, LaMarca, Lee, Liu, Marone, Maslova, Mei, Olayioye, Omori, Pollheimer, Robertson, Spindle, Stefanidou, Tsygankova, Wadge, Weng, Yarden, Yarden, Yoshino, Zhang, Zoncu   +46 more
core   +1 more source