Inadequate invasion and excessive apoptosis of trophoblast cells are associated with the development of preeclampsia. Vitamin D deficiency in pregnant women may lead to an increased risk of preeclampsia.
Xiaoyu Tian+5 more
doaj +1 more source
Here and there a trophoblast, a transcriptional evaluation of trophoblast cell models
Abstract A recent explosion of methods to produce human trophoblasts and stem cells (hTSC) is fuelling a renewed interest in this tissue. The trophoblast is critical to reproduction by facilitating implantation, maternal physiological adaptations to pregnancy and the growth of the fetus through transport of nutrients between the mother and ...
Brian Joseph Cox, Kendra Naismith
openaire +2 more sources
Convergent evolution of pregnancy-specific glycoproteins in human and horse [PDF]
Pregnancy-specific glycoproteins (PSGs) are members of the carcinoembryonic antigen cell adhesion molecule (CEACAM) family that are secreted by trophoblast cells. PSGs may modulate immune, angiogenic and platelet responses during pregnancy.
Amanda M de Mestre+16 more
core +1 more source
A Semantic Segmentation Network Based Real-Time Computer-Aided Diagnosis System for Hydatidiform Mole Hydrops Lesion Recognition in Microscopic View [PDF]
As a disease with malignant potential, hydatidiform mole (HM) is one of the most common gestational trophoblastic diseases. For pathologists, the HM section of hydrops lesions is an important basis for diagnosis. In pathology departments, the diverse microscopic manifestations of HM lesions and the limited view under the microscope mean that physicians
arxiv
Epithelioid trophoblastic tumor
To describe a case of epithelioid trophoblastic tumor (ETT) in a postmenopausal woman, which had several peculiar features that differentiate it from previously reported ETTs.ETT of the uterus is a rare form of trophoblastic tumor with only 100 cases distinguished until now.
Caglar Cakir+5 more
openaire +4 more sources
Gene expression analysis of bovine embryonic disc, trophoblast and parietal hypoblast at the start of gastrulation [PDF]
In cattle early gastrulation-stage embryos (Stage 5), four tissues can be discerned: (i) the top layer of the embryonic disc consisting of embryonic ectoderm (EmE); (ii) the bottom layer of the disc consisting of mesoderm, endoderm and visceral hypoblast
Berg, D+3 more
core +2 more sources
RBM10 Regulates Embryonic Trophoblast Injury via Endoplasmic Reticulum Stress
Background: Previous studies shown that RNA binding motif proteins (RBM) participate in regulating various physiological processes such as cell autophagy, proliferation, and apoptosis, and are abnormally highly expressed in placental trophoblast cells ...
Xiao Chen+4 more
doaj +1 more source
Formation of atypical podosomes in extravillous trophoblasts regulates extracellular matrix degradation [PDF]
Throughout pregnancy the cytotrophoblast, the stem cell of the placenta, gives rise to the differentiated forms of trophoblasts. The two main cell lineages are the syncytiotrophoblast and the invading extravillous trophoblast.
Alexander+37 more
core +2 more sources
Brucella abortus Infection of Placental Trophoblasts Triggers Endoplasmic Reticulum Stress-Mediated Cell Death and Fetal Loss via Type IV Secretion System-Dependent Activation of CHOP. [PDF]
Subversion of endoplasmic reticulum (ER) function is a feature shared by multiple intracellular bacteria and viruses, and in many cases this disruption of cellular function activates pathways of the unfolded protein response (UPR).
Atluri, Vidya L+14 more
core +1 more source
The placenta is crucial for a successful pregnancy and the health of both the fetus and the pregnant woman. However, how the human trophoblast lineage is regulated, including the categorization of the placental cell subtypes is poorly understood. Here we
Yawei Liu+10 more
semanticscholar +1 more source