Results 91 to 100 of about 4,124 (226)
Super‐Resolution Microscopy in Tissue Engineering
Advanced Materials Interfaces, Volume 12, Issue 19, October 6, 2025.Super‐resolution microscopy (SRM) has advanced tissue engineering by providing nanoscale insights into cellular interactions. It reveals detailed cell membrane structures, tracks vesicle and virus entry, and visualizes the cytoskeleton. SRM also improves understanding of cell migration, facilitating tissue regeneration, vascularization, immune ...
Navid Rabiee +2 more
wiley +1 more source
Functional Classification of Skeletal Muscle Networks. I. Normal Physiology [PDF]
, 2012 Extensive measurements of the parts list of human skeletal muscle through transcriptomics and other phenotypic assays offer the opportunity to reconstruct detailed functional models.
Subramaniam, Shankar +2 more
core +2 more sources
Advanced Science, Volume 12, Issue 37, October 6, 2025.Cardiovascular disease (CVD) and cancer are leading causes of death worldwide, with overlapping risk factors and pathophysiological mechanisms. This review explores shared pathways, including metabolic dysregulation, chronic inflammation, and gut microbiome alterations, highlighting dual‐benefit strategies such as lifestyle modifications and repurposed
Shihan Xiang +6 more
wiley +1 more source
Gene Assignment, Expression, and Homology of Human Tropomodulin
Genomics, 1996 Tropomodulin is a newly characterized pointed end capping protein for actin filaments. It binds specifically to the N terminus of tropomyosin and blocks the elongation and depolymerization of tropomyosin-coated actin filaments. A 1.9-kb human tropomodulin cDNA clone was used to map its gene by fluorescence in situ hybridization.
L A, Sung, Y, Fan, C C, Lin
openaire +2 more sources
Murine obscurin and Obsl1 have functionally redundant roles in sarcolemmal integrity, sarcoplasmic reticulum organization, and muscle metabolism. [PDF]
, 2019 Biological roles of obscurin and its close homolog Obsl1 (obscurin-like 1) have been enigmatic. While obscurin is highly expressed in striated muscles, Obsl1 is found ubiquitously.
Blondelle, Jordan +13 more
core +1 more source
The FEBS Journal, 2019 Tropomyosin (Tpm) binds along actin filaments and regulates myosin binding to control muscle contraction. Tropomodulin binds to the pointed end of a filament and regulates actin dynamics, which maintains the length of a thin filament.
J. Moraczewska +7 more
semanticscholar +1 more source
Circulation, 2020 Circulation. 2020;142:e450–e451. DOI: 10.1161/CIRCULATIONAHA.120.047575 e450 Xin Liu , MD Junjie Guo, PhD Haichu Yu, MD To the Editor: We read with interest the article by Xu et al,1 who report that branched-chain amino acids (BCAAs) catabolism is an ...
Xin Liu, Junjie Guo, Haichu Yu
semanticscholar +1 more source
Tropomodulin caps the pointed ends of actin filaments. [PDF]
The Journal of cell biology, 1994 Many proteins have been shown to cap the fast growing (barbed) ends of actin filaments, but none have been shown to block elongation and depolymerization at the slow growing (pointed) filament ends. Tropomodulin is a tropomyosin-binding protein originally isolated from red blood cells that has been localized by immunofluorescence staining to a site at ...
A, Weber +3 more
openaire +2 more sources
Super-Resolution Microscopy Reveals the Native Ultrastructure of the Erythrocyte Cytoskeleton
Cell Reports, 2018 Summary: The erythrocyte cytoskeleton is a textbook prototype for the submembrane cytoskeleton of metazoan cells. While early experiments suggest a triangular network of actin-based junctional complexes connected by ∼200-nm-long spectrin tetramers, later
Leiting Pan, Rui Yan, Wan Li, Ke Xu
doaj +1 more source
Tropomodulin 3 promotes liver cancer progression by activating the MAPK/ERK signaling pathway.
Oncology Report, 2019 Tropomodulin 3 (TMOD3) is a member of the pointed‑end capping protein family that contributes to invasion and metastasis in several types of malignancies.
Can-guang Jin +3 more
semanticscholar +1 more source