Results 81 to 90 of about 4,124 (226)

Domain structure of tropomodulin [PDF]

European Journal of Biochemistry, 2000
The structure of tropomodulin, the unique capping protein for the pointed end (the slow‐growing end) of an actin filament, was studied. An improved Escherichia coli expression system for chicken E‐tropomodulin was established and tropomodulin was prepared, Tmod (N39), in which 15 amino acid residues from the original C‐terminus are deleted at the DNA ...
A, Kostyukova, K, Maeda, E, Yamauchi, I, Krieger, Y, Maéda   +4 more
openaire   +2 more sources

Tropomyosin - master regulator of actin filament function in the cytoskeleton. [PDF]

, 2015
Tropomyosin (Tpm) isoforms are the master regulators of the functions of individual actin filaments in fungi and metazoans. Tpms are coiled-coil parallel dimers that form a head-to-tail polymer along the length of actin filaments.
Alenghat, Ang, Bach, Balasubramanian, Bernstein, Bharadwaj, Boyd, Broschat, Bryce, Bugyi, Caldwell, Clayton, Colón-Franco, Coulton, Creed, Curthoys, Dalby-Payne, Egelman, Fanning, Fath, Fischer, Fowler, Galkin, Galkin, Geeves, Geeves, Gimona, Goins, Gunning, Gunning, Hendricks, Hendricks, Hitchcock-DeGregori, Hodges, Holmes, Hook, Hook, Hotulainen, Ishikawa, Ishikawa, Jagatheesan, Jagatheesan, Jalilian, Johnson, Kee, Kee, Kee, Kis-Bicskei, Klip, Kojima, Korobova, Korobova, Kotadiya, Kuhn, Lazarides, Lazarides, Lees, Lehman, Lehrer, Leonardi, Li, Lim, Lin, Liu, Liu, Marguerat, Martin, Martin, Marttila, Matsumura, McCullough, McIntosh, McMichael, McMichael, Michelot, Miyado, Miyado, Muthuchamy, Nakano, Novy, Ono, Papp, Pelham, Percival, Prasad, Ramabhadran, Rao, Raval, Rethinasamy, Schevzov, Schevzov, Schevzov, Schevzov, Schevzov, Schulze, Singh, Skau, Skoumpla, Stark, Stehn, Stehn, Tang, Temm-Grove, Thoms, Tobacman, Tojkander, Tojkander, Ujfalusi, Urbancíková, Vera, Vindin, Vlahovich, Vlahovich, von der Ecken, Wakatsuki, Warren, Wawro, Wegner, Zucchi   +118 more
core   +1 more source

Leiomodin 3 and Tropomodulin 4 have overlapping functions during skeletal myofibrillogenesis [PDF]

Journal of Cell Science, 2014
Chinedu U. Nworu, Robert Kraft, Daniel C. Schnurr, Carol C. Gregorio, Paul A. Krieg   +4 more
openalex   +2 more sources

Intrinsic structural disorder in cytoskeletal proteins. [PDF]

, 2013
Cytoskeleton, the internal scaffold of the cell, displays an exceptional combination of stability and dynamics. It is composed of three major filamentous networks, microfilaments (actin filaments), intermediate filaments (neurofilaments), and ...
Beata Szabo, Mainak Guharoy, Peter Tompa, Sara Contreras Martos, Simone Kosol   +4 more
core   +1 more source

Leiomodin-3 dysfunction results in thin filament disorganization and nemaline myopathy [PDF]

, 2014
Peer ...
Adele D’Amico, Agrawal, Alan H. Beggs, Alla S. Kostyukova, Anders Flisberg, Ann E. Davidson, Annie Laquerrière, Biljana Ilkovski, Brett P. Thomas, Carina Wallgren-Pettersson, Carol C. Gregorio, Carsten G. Bönnemann, Catherine A. Brownstein, Chereau, Christopher T. Pappas, Coen A.C. Ottenheijm, Cooper, Daniel G. MacArthur, Darcée D. Sloboda, David Chitayat, David P. Bick, David S. Gokhin, de Winter, Edoardo Malfatti, Emily J. Todd, Enrico Bertini, Eva Holmberg, Flora Nolent, Gianina Ravenscroft, Gokhin, Granzier, Greenfield, Ichizo Nishino, James J. Dowling, Judith Melki, Jérome Maluenda, Katarina Pelin, Kate G. Quinlan, Kathryn N. North, Kostyukova, Kouyama, Leigh B. Waddell, Lindsay C. Swanson, Livija Medne, Majczenko, Mark J. Daly, Menezes, Michaela Yuen, Monkol Lek, Namrata Gupta, Nanda, Natalia Moroz, Nicole Martin, Nigel F. Clarke, Nigel G. Laing, Norma B. Romero, Ozge Ceyhan-Birsoy, Pablo Lapunzina, Patrick Shannon, Peter J. Houweling, Peter Van den Bergh, Ravenscroft, Ryan, Sarah A. Sandaradura, Sloboda, Stacey B. Gabriel, Stefanie M. Novak, Telfer, Tsukada, Vandana A. Gupta, Velia M. Fowler, Vilma-Lotta Lehtokari, William R. Telfer, Yukiko K. Hayashi   +73 more
core   +1 more source

Evolution of Plasticity in Response to Ethanol Between Recently Separated Populations of D. melanogaster With Different Ecological Histories

Ecology and Evolution, Volume 16, Issue 1, January 2026.
We identified: (1) differences in gene expression among each locale; (2) changes in gene expression in response to treatment; (3) genotype‐specific changes in gene expression in response to treatment. ABSTRACT While there is abundant theoretical work on the evolution of phenotype plasticity, empirical support has lagged.
George Boateng‐Sarfo, Franz Scherping, Murad Mammadov, Sarah Signor   +3 more
wiley   +1 more source

Loss of Tropomodulin4 in the zebrafish mutant träge causes cytoplasmic rod formation and muscle weakness reminiscent of nemaline myopathy

Disease Models & Mechanisms, 2014
Nemaline myopathy is an inherited muscle disease that is mainly diagnosed by the presence of nemaline rods in muscle biopsies. Of the nine genes associated with the disease, five encode components of striated muscle sarcomeres.
Joachim Berger, Hakan Tarakci, Silke Berger, Mei Li, Thomas E. Hall, Anders Arner, Peter D. Currie   +6 more
doaj   +1 more source

Role of active contraction and tropomodulins in regulating actin filament length and sarcomere structure in developing zebrafish skeletal muscle

Frontiers in Physiology, 2016
Whilst it is recognised that contraction plays an important part in maintaining the structure and function of mature skeletal muscle, its role during development remains undefined.
Lise eMazelet, Matt O Parker, Mei eLi, Arner eAnders, Rachel eAshworth   +4 more
doaj   +1 more source

Response by Xu et al to Letter Regarding Article, "Branched-Chain Amino Acid Catabolism Promotes Thrombosis Risk by Enhancing Tropomodulin-3 Propionylation in Platelets".

Circulation, 2020
Circulation. 2020;142:e452–e453. DOI: 10.1161/CIRCULATIONAHA.120.051367 e452 Yanyan Xu, PhD Haojie Jiang, PhD Junling Liu, PhD In Response: We thank Dr Liu and colleagues for their interest in our article, “Branched-Chain Amino Acid Catabolism Promotes ...
Yanyan Xu, Haojie Jiang, Junling Liu
semanticscholar   +1 more source

Formation, contraction, and mechanotransduction of myofribrils in cardiac development: clues from genetics [PDF]

, 2012
Congenital heart disease (CHD) is the most common birth defect in humans. It is a leading infant mortality factor worldwide, caused by defective cardiac development.
Brook, David, Granados-Riveron, Javier T.   +1 more
core   +5 more sources