Results 31 to 40 of about 19,854,960 (401)

Which diagnostic tests are most useful in a chest pain unit protocol? [PDF]

, 2005
Background The chest pain unit (CPU) provides rapid diagnostic assessment for patients with acute, undifferentiated chest pain, using a combination of electrocardiographic (ECG) recording, biochemical markers and provocative cardiac testing.
Angelini, K., Arnold, J., Goodacre, S., Locker, T., Morris, F.   +4 more
core   +3 more sources

Prognostic importance of emerging cardiac, inflammatory, and renal biomarkers in chronic heart failure patients with reduced ejection fraction and anaemia: RED-HF study [PDF]

, 2018
Aims: To test the prognostic value of emerging biomarkers in the Reduction of Events by Darbepoetin Alfa in Heart Failure (RED-HF) trial. Methods and results: Circulating cardiac [N-terminal pro-B-type natriuretic peptide (NT-proBNP), and high ...
Alehagen, Arimoto, Balling, Bolignano, Cabassi, Dupont, Gaggin, Gravning, Grodin, Guisado Espartero, Haehling, Harrell, Jackson, Lassus, Lassus, Lok, Maisel, Maisel, McMurray, McMurray, Miller, Miller, Nagarajan, Park, Pascual-Figal, Pencina, Pencina, Pocock, Ponikowski, Rahimi, Rush, Shlipak, Swedberg, Tentzeris, Zamora   +34 more
core   +4 more sources

Characterization of a Cardiac Troponin C-Troponin I Chimera Protein [PDF]

Biophysical Journal, 2013
Association of the regulatory N-domain of cardiac troponin C (cNTnC) with the switch region of cardiac troponin I (cTnI147-163) is a major step in Ca2+ regulation of myocardial contraction by troponin as it triggers a series of downstream events that leads to contraction.
Sandra E. Pineda-Sanabria, Monica X. Li, Olivier Julien, Brian D. Sykes   +3 more
openaire   +2 more sources

The 99th percentile of reference population for cTnI and cTnT assay: Methodology, pathophysiology and clinical implications [PDF]

, 2017
According to recent international guidelines, including the 2012 Third Universal Definiton of Myocardial Infarction by the Joint ESC/ACCF/AHA/WHF Task Force, an increase in cardiac troponin (cTn) levels over the 99th percentile upper reference limit ...
Clerico, Aldo, Masotti, Silvia, Passino, Claudio, Plebani, Mario, Prontera, Concetta, Ripoli, Andrea, Zaninotto, Martina   +6 more
core   +1 more source

Differentiation between myopericarditis and acute myocardial infarction on presentation in the emergency department using the admission C-reactive protein to troponin ratio.

PLoS ONE, 2021
BackgroundThe treatment of myopericarditis is different than that of acute myocardial infarction (AMI). However, since their clinical presentation is frequently similar it may be difficult to distinguish between these entities despite a disparate ...
Simcha R Meisel, Hamuda Nashed, Randa Natour, Rami Abu Fanne, Majdi Saada, Naama Amsalem, Carmel Levin, Ofer Kobo, Aaron Frimerman, Yaniv Levi, Jameel Mohsen, Avraham Shotan, Ariel Roguin, Michael Kleiner-Shochat   +13 more
doaj   +1 more source

The isolation of differentially expressed cDNA clones from the filarial nematode Brugia pahangi [PDF]

, 1999
A cDNA library constructed from 3 day post-infective L3 of the filarial nematode Brugia pahangi was screened by differential hybridization with cDNA probes prepared from different life-cycle stages.
Devaney, E., Hunter, S.J., Martin, S.A., Tetley, L., Thompson, F.J.   +4 more
core   +1 more source

Cardiac troponin I but not cardiac troponin T adheres to polysulfone dialyser membranes in an in vitro haemodialysis model: explanation for lower serum cTnI concentrations following dialysis. [PDF]

, 2014
BACKGROUND: Elevated serum cardiac troponin T (cTnT) and I (cTnI) can occur in patients with chronic kidney disease. Differences in cTn concentrations between cTnT and cTnI have been reported but the mechanism of such discrepancy has not been ...
Adams, Beciani, Bhayana, Boulier, Collinson, Collinson, Collinson, Conway, Deegan, Donnino, Frankel, Hickman, Katrukha, Keller, Khan, Krummel, Lippi, Lowbeer, Mockel, Morrow, Muller-Bardorff, Orea-Tejeda, Peetz, Reichlin, Sahinarslan, Sharma, Sommerer, Stoffel, Tarakcioglu, Thygesen, Tomisawa, Wang, Wayand   +32 more
core   +1 more source

The Rates of Ca2+ Dissociation and Cross-bridge Detachment from Ventricular Myofibrils as Reported by a Fluorescent Cardiac Troponin C*

Journal of Biological Chemistry, 2012
Background: The rate-limiting step of cardiac muscle relaxation is not completely understood. Results: We were able to measure two proposed rate-limiting steps of relaxation in ventricular myofibrils.
Sean C. Little, B. Biesiadecki, A. Kilic, Robert S. D. Higgins, P. Janssen, Jonathan P. Davis   +5 more
semanticscholar   +1 more source

Prognostic value of troponins in acute coronary syndrome depends upon patient age [PDF]

, 2014
Peer ...
Bachmann, M. O., Kwok, C. S., Myint, P. K., Shepstone, L., Stirling, S., Zaman, M. J. S.   +5 more
core   +1 more source

Molecular Basis of Calcium-Sensitizing and Desensitizing Mutations of the Human Cardiac Troponin C Regulatory Domain: A Multi-Scale Simulation Study

PLoS Comput. Biol., 2012
Troponin C (TnC) is implicated in the initiation of myocyte contraction via binding of cytosolic and subsequent recognition of the Troponin I switch peptide.
P. Kekenes-Huskey, S. Lindert, J. McCammon   +2 more
semanticscholar   +1 more source