Analysis of myofibrillar and sarcoplasmic proteins in pork meat by capillary gel electrophoresis
Foods and Raw Materials, 2018 Myofibrillar and sarcoplasmic proteins were extracted from pork meat (M. Longissimus dorsi) and then separated by capillary gel electrophoresis (CGE). Migration time and peak areas of individual protein molecules in the electropherogram were analysed ...
Radoslav Grujić, Danica Savanović
doaj +1 more source
Evaluation of troponin I and C in horses intoxicated by salinomycin
Pesquisa Veterinária Brasileira, 2023 : Ionophores are antibiotics frequently used in animals of production. The most common are monensin, salinomycin, narasin, and lasalocid. The equine species is highly susceptible to ionophores poisoning.
Camila B. Pohl +7 more
doaj +1 more source
Influence of case definition on incidence and outcome of acute coronary syndromes [PDF]
, 2016 © 2016, BMJ Publishing Group. All rights reserved. Objective: Acute coronary syndromes (ACS) are common, but their incidence and outcome might depend greatly on how data are collected.
Alamgir, Farqad +11 more
core +2 more sources
Journal of Biological Chemistry, 2012 Background: Cardiac troponin C mutations are rare causes of HCM. A novel mutation in TNNC1 gene was identified in a pediatric HCM patient. Results: Functional characterization demonstrated increased myofilament Ca2+ affinity.
Michelle S. Parvatiyar +5 more
semanticscholar +1 more source
Engineered Troponin C Constructs Correct Disease-related Cardiac Myofilament Calcium Sensitivity*
Journal of Biological Chemistry, 2012 Background: Improved myofilament Ca2+ sensitivity alleviates defects in thin filament bearing disease-causing mutations. Results: By engineering the cardiac muscle Ca2+ sensor troponin C, aberrant myofilament Ca2+ sensitivity can be corrected in vitro ...
B. Liu +4 more
semanticscholar +1 more source
Irisin regulates cardiac physiology in zebrafish.
PLoS ONE, 2017 Irisin is a myokine encoded in its precursor fibronectin type III domain containing 5 (FNDC5). It is abundantly expressed in cardiac and skeletal muscle, and is secreted upon the activation of peroxisome proliferator-activated receptor gamma coactivator ...
Lakshminarasimhan Sundarrajan +4 more
doaj +1 more source
The role of cardiac troponin T quantity and function in cardiac development and dilated cardiomyopathy [PDF]
, 2008 Background: Hypertrophic (HCM) and dilated (DCM) cardiomyopathies results from sarcomeric protein mutations, including cardiac troponin T (cTnT, TNNT2).
Ahmad, F +17 more
core +4 more sources
Drug Binding to Cardiac Troponin C [PDF]
Journal of Biological Chemistry, 1999 Compounds that sensitize cardiac muscle to Ca(2+) by intervening at the level of regulatory thin filament proteins would have potential therapeutic benefit in the treatment of myocardial infarctions. Two putative Ca(2+) sensitizers, EMD 57033 and levosimendan, are reported to bind to cardiac troponin C (cTnC).
John A. Putkey, Quinn Kleerekoper
openaire +3 more sources
Familial hypertrophic cardiomyopathy related cardiac troponin C L29Q mutation alters length-dependent activation and functional effects of phosphomimetic troponin I*. [PDF]
PLoS ONE, 2013 The Ca(2+) binding properties of the FHC-associated cardiac troponin C (cTnC) mutation L29Q were examined in isolated cTnC, troponin complexes, reconstituted thin filament preparations, and skinned cardiomyocytes. While higher Ca(2+) binding affinity was
Alison Y Li +6 more
doaj +1 more source
High-sensitivity cardiac troponin T and copeptin assays to improve diagnostic accuracy of exercise stress test in patients with suspected coronary artery disease [PDF]
, 2014 Background: The average diagnostic sensitivity of exercise stress tests (ESTs) is lower than that of other non-invasive cardiac stress tests. The aim of the study was to examine whether high-sensitivity cardiac troponin T (hs-cTnT) or copeptin ...
Dörr, Oliver +9 more
core +1 more source