Results 41 to 50 of about 43,375 (307)
Cardiospecific troponins in non-ischemic cardiological pathologies
Cardiospecific troponin T (TnT) and I (TnI) are low-molecularweight proteins that form part of the troponin complex and are integral components of the myofibrillar contractile apparatus of the heart.
Giuseppe Lippi+2 more
doaj +1 more source
Interaction of aldolase with the troponin–tropomyosin complex of bovine muscle [PDF]
Ultracentrifugal studies of mixtures of aldolase and the troponin–tropomyosin complex from bovine muscle showed the existence of a labile interaction between these two myofibrillar constituents in imidazole buffers, pH6.8, I 0.02–0.10 (mol/l), and the suppression of the reaction by fructose 1,6-diphosphate.
Clarke F.M., Masters C.J., Winzor D.J.
openaire +4 more sources
Hybrid NPs are developed as efficient, scalable nanocarriers for in vitro microRNA delivery, ensuring high loading efficiency, controlled release, physiological and long‐term storage stability. They outperform commercial lipid‐based reagents in terms of transfection efficiency and biocompatibility.
Letizia Nicoletti+11 more
wiley +1 more source
False-positive troponin elevation due to an immunoglobulin-G-cardiac troponin T complex: a case report [PDF]
Abstract Background Troponin is a crucial biomarker for the diagnosis of an acute coronary syndrome (ACS). It rises in response to myocardial injury from significant acute myocardial ischaemia caused by obstructive coronary artery disease [‘classical’ myocardial infarction (MI)].
Paul Collinson+6 more
openaire +3 more sources
This review explores the transformative role of AI in biosensor technology and provides a holistic interdisciplinary perspective that covers a broader scope of AI‐enabled biosensor technologies across various sectors including healthcare, environmental monitoring, food safety, and agriculture. It also highlights the important role of novel materials in
Tuğba Akkaş+4 more
wiley +1 more source
Detecting single molecules on large interfaces is challenging due to minimal perturbations on the sensing surface. Some biological systems achieve this feat using amplification mechanisms, but their molecular foundations remain unclear. To investigate, a Design of Experiments (DoE) approach examines how pH and ionic strength in conditioning solutions ...
Michele Catacchio+9 more
wiley +1 more source
Mutations in TNNC1—the gene encoding cardiac troponin C (cTnC)—that have been associated with hypertrophic cardiomyopathy (HCM) and cardiac dysfunction may also affect Ca2+-regulation and function of slow skeletal muscle since the same gene is expressed ...
Jose R. Pinto+9 more
doaj +1 more source
Progress in Surface Plasmon and Other Resonance Biosensors for Biomedical Applications
This is the shortened version: Recent advancements in surface plasmon resonance and other optical resonance biosensors for biomedical applications are presented. Advanced sensing strategies are examined for the detection of diverse analytes, integration of nanomaterials and machine learning, and emerging nonplasmonic modes like guided mode resonance ...
Faten Bashar Kamal Eddin+8 more
wiley +1 more source
Toll-Like Receptor-Mediated Cardiac Injury during Experimental Sepsis
Sepsis is associated with global cardiac dysfunction and with high mortality rate. The development of septic cardiomyopathy is due to complex interactions of damage-associated molecular patters, cytokines, and complement activation products.
Ina Lackner+6 more
doaj +1 more source
PKCα-specific phosphorylation of the troponin complex in human myocardium: a functional and proteomics analysis. [PDF]
AIMS:Protein kinase Cα (PKCα) is one of the predominant PKC isoforms that phosphorylate cardiac troponin. PKCα is implicated in heart failure and serves as a potential therapeutic target, however, the exact consequences for contractile function in human ...
Viola Kooij+12 more
doaj +1 more source