Results 51 to 60 of about 6,673,815 (394)

Predictors and morphological properties of culprit healed plaques in patients with angina pectoris

Clinical Cardiology, Volume 45, Issue 12, Page 1199-1210, December 2022., 2022
Abstract Background Plaque healing may serve a vital function in the natural progression of atherosclerotic disease. This study sought to investigate predictors and morphological characteristics of healed plaque (HP) among angina pectoris (AP) patients.
Hongying Yao, Qianyun Guo, Yujing Cheng, Tianyu Zhu, Qian Ma, Yujie Zhou   +5 more
wiley   +1 more source

Comparison of ARCHITECT chemiluminiscent microparticle immunoassay for determination of Troponin I in serum with AXYM MEIA technology

Journal of Health Sciences, 2011
Introduction: The aim of this study was determination of troponin I at serum using Architect (Abbott) and AxSYM System (Abbott). Troponin is regulatory subunit of the troponin complex associate with actin filament within muscle cells and it is a marker ...
Nafija Serdarević
doaj   +1 more source

Effects of troponin T cardiomyopathy mutations on the calcium sensitivity of the regulated thin filament and the actomyosin cross-bridge kinetics of human β-cardiac myosin. [PDF]

PLoS ONE, 2013
Hypertrophic cardiomyopathy (HCM) and dilated cardiomyopathy (DCM) lead to significant cardiovascular morbidity and mortality worldwide. Mutations in the genes encoding the sarcomere, the force-generating unit in the cardiomyocyte, cause familial forms ...
Ruth F Sommese, Suman Nag, Shirley Sutton, Susan M Miller, James A Spudich, Kathleen M Ruppel   +5 more
doaj   +1 more source

Investigating the role of uncoupling of troponin I phosphorylation from changes in myofibrillar Ca(2+)-sensitivity in the pathogenesis of cardiomyopathy. [PDF]

, 2014
Contraction in the mammalian heart is controlled by the intracellular Ca2+ concentration as it is in all striated muscle, but the heart has an additional signalling system that comes into play to increase heart rate and cardiac output during exercise or ...
Marston, SB, Messer, AE
core   +2 more sources

Prognosis of PCI in AMI setting in the elderly population: Outcomes from the multicenter prospective e‐ULTIMASTER registry

Clinical Cardiology, Volume 45, Issue 12, Page 1211-1219, December 2022., 2022
Abstract Background Elderly patients with ST‐elevation myocardial infarction (STEMI) who undergo percutaneous coronary intervention (PCI) are usually excluded from major trials. Hyopthesis This study sought to assess 1‐year clinical outcomes following PCI with a drug‐eluting stent in patients older than 80 years old with STEMI.
Majdi Saada, Ofer Kobo, Jawed Polad, Majdi Halabi, Alexander J. J. IJsselmuiden, Ángel Puentes, Jacques Monségu, David Austin, Ruslan K. Baisebenov, Fabrizio Spanó, Ariel Roguin, e‐ULTIMASTER Investigators   +11 more
wiley   +1 more source

A Case Series of Disproportionate Elevations of Cardiac Troponin and Macrotroponin in Fabry Disease [PDF]

Journal of Inborn Errors of Metabolism and Screening
Fabry disease is a rare X-linked lysosomal storage disorder that causes progressive cellular accumulation of glycosphingolipids, leading to various end-organ manifestations such as chronic kidney disease and cardiomyopathy.
Yvonne Moussa, Cankayan Suthaharen, Kerry Devine, Michel Tchan, Rebecca Kozor, Yusof Rahman   +5 more
doaj   +1 more source

Troponins, Acute Coronary Syndrome and Renal Disease: From Acute Kidney Injury Through End-stage Kidney Disease [PDF]

, 2019
The diagnosis of acute coronary syndromes (ACS) is heavily dependent on cardiac biomarker assays, particularly cardiac troponins. ACS, particularly non-ST segment elevation MI, are more common in patients with acute kidney injury, chronic kidney disease (
Banerjee, A, Banerjee, D, Ferrett, C
core   +2 more sources

Biosensors for cardiac biomarkers detection: a review [PDF]

, 2012
The cardiovascular disease (CVD) is considered as a major threat to global health. Therefore, there is a growing demand for a range of portable, rapid and low cost biosensing devices for the detection of CVD.
Gurbuz, Yasar, Gürbüz, Yaşar, Kolkar Mohammed, Javed Hussain Niazi, Qureshi, Anjum   +3 more
core   +1 more source

Molecular characterization of the immediate wound response of the solitary ascidian Polycarpa mytiligera

Developmental Dynamics, Volume 251, Issue 12, Page 1968-1981, December 2022., 2022
Abstract Background Injury response is key to successful regeneration. Yet, transcriptome analyses of injury response were performed only on a handful of regenerative organisms. Here, we studied the injury response of the solitary ascidian Polycarpa mytiligera, an emerging model system, capable of regenerating any body part.
Noam Hendin, Tal Gordon, Noa Shenkar, Omri Wurtzel   +3 more
wiley   +1 more source

Dynamics and calcium association to the N-terminal regulatory domain of human cardiac troponin C: a multiscale computational study. [PDF]

, 2012
Troponin C (TnC) is an important regulatory molecule in cardiomyocytes. Calcium binding to site II in TnC initiates a series of molecular events that result in muscle contraction.
Huber, Gary, Kekenes-Huskey, Peter M, Lindert, Steffen, McCammon, J Andrew, Pierce, Levi   +4 more
core   +2 more sources