Results 131 to 140 of about 2,565,891 (293)

Loading regimen required to rapidly achieve therapeutic trough plasma concentration of teicoplanin and evaluation of clinical features

, 2012
Masafumi Seki,1,* Kaori Yabuno,1,2,* Koji Miyawaki,1,2 Yoshihiro Miwa,2 Kazunori Tomono11Division of Infection Control and Prevention, 2Department of Pharmacy, Osaka University Hospital, Suita, Osaka, Japan*These authors contributed equally to this ...
Yabuno K, Miyawaki K, Miwa Y, Seki M, Tomono K   +4 more
core  

Plasma trough concentration of Imatinib (400mg) in genotypes of rs2242480

Plasma trough concentration of Imatinib (400mg) in genotypes of ...
Asma Khan (18159340)
core   +1 more source

Development of Receivers for the DSG Process [PDF]

, 2006
The direct steam generation (DSG) in parabolic trough collectors is a promising option for improving the mature SEGS type parabolic trough solar thermal power plant technology. The European DISS and INDITEP projects have proven the feasibility of the DSG
Uhlig, Ralf, Benz, Nikolaus, Kuckelkorn, Thomas, Eck, Markus   +3 more
core  

GHRHR Deficiency Enhances Retinal Ganglion Cell Survival and Visual Functions in Experimental Glaucoma by Inhibiting Ferroptosis

Advanced Science, EarlyView.
Glaucoma, a major cause of blindness, involves retinal ganglion cell (RGC) degeneration. This study shows growth hormone‐releasing hormone receptor (GHRHR) deficiency preserves RGC survival and restores vision, unlike activation which only aids survival.
Yan Tong, Ming Ho Yam, Jiaxin Zhang, Lin Du, Linbin Zhou, Yolanda Wong Ying Yip, Bo Man Ho, Hemlata Bisnauthsing, Jiahui Li, Ivan Kong, Shushu Xu, Changzhen Fu, Karl K.H. So, Joaquim S.L. Vong, Ling‐Ping Cen, Ming‐Ming Yang, Khazeema Yousaf, Mai Har Sham, Sun On Chan, Poemen P. Chan, Chi Pui Pang, Clement C. Tham, Jing Na He, Jian Li, Wai Kit Chu   +24 more
wiley   +1 more source

A twin study of the trough plasma steady-state concentration of metformin

, 2015
OBJECTIVE: The aim of this study was to determine the intrapair similarity in trough steady-state plasma concentrations of metformin in monozygotic and dizygotic twin pairs.METHODS: We included 16 twin pairs (eight monozygotic and eight dizygotic twin ...
Damkier, Per; id_orcid, Pedersen, Rasmus S, Christiansen, Lene, Stage, Tore B; id_orcid, Christensen, Mette M H, Christensen, Kaare; id_orcid, Brosen, Kim   +6 more
core   +1 more source

Lactiplantibacillus Plantarum GUANKE Alleviates Allergic Asthma by Restricting Monocyte‐to‐DC Differentiation Via Microbiota‐Associated IAA

Advanced Science, EarlyView.
Lactiplantibacillus plantarum GUANKE remodels the indigenous gut microbiota and is associated with microbiota‐dependent restoration of circulating IAA. IAA treatment attenuates JAK3‐STAT3 and Jag1‐Notch4‐Hey1 signaling and reduces CX3CR1+Ly6C− monocytic precursor generation and pulmonary CD11b+ DC accumulation, together with reduced Th2 inflammation ...
Yujia He, Jielan Mi, Zhiping Zhao, Xiao Zhang, Zhihan Yang, Kun Yue, Yuanming Huang, Liqiong Song, Xiaoting Wen, Jianguo Xu, Zhihong Ren   +10 more
wiley   +1 more source

Is it time to recommend AUC-based vancomycin therapeutic drug monitoring only? A cross-sectional survey in China

Frontiers in Pharmacology
BackgroundThe latest published therapeutic drug monitoring (TDM) guidelines for vancomycin recommend changing trough-based monitoring to area under the concentration-to-time curve (AUC)-based monitoring.
Jieqiong Liu, Jieqiong Liu, Xuan Zhang, Gang Liang, Jianping Zhu, Yi Yang, Ying Zheng, Yun Han, Yun Han, Yun Han, Lingyan Yu, Lingyan Yu, Yuhua Zhao, Zhenwei Yu, Zhenwei Yu   +14 more
doaj   +1 more source

Determinants of Financial Stress and Recovery during the Great Recession [PDF]

In this paper, we explore the link between stress in the domestic financial sector and the capital flight faced by countries in the 2008-9 global crisis.
Gurnain Kaur Pasricha, Joshua Aizenman
core  

Polychip‐A High‐Throughput Droplet Microfluidics Platform for Interrogating Microbial Interactions

Advanced Science, EarlyView.
Polychip, a fully integrated droplet microfluidics platform, enables high‐throughput, single‐cell resolution screening of polymicrobial interactions. By seamlessly combining six automated microfluidics operations on a single chip, the system accelerates antimicrobial discovery by 11 to 14 times compared to traditional robotic methods.
Jeong Jae Han, Adrian Ryan Guzman, Aifen Zhou, Han Zhang, Rohit Gupte, Haemin Jung, Kaylee Delgado, Sini Skariah, Ali Sultan, Arul Jayaraman, Paul de Figueiredo, Arum Han   +11 more
wiley   +1 more source

Machine learning approach for personalized vancomycin steady-state trough concentration prediction: a superior approach over Bayesian population pharmacokinetic model

Frontiers in Pharmacology
IntroductionAppropriate vancomycin trough levels are crucial for ensuring therapeutic efficacy while minimizing toxicity. The aim of this study is to identify clinical factors that influence the steady-state trough concentration of vancomycin and to ...
Ting Hu, Xian Ding, Feifei Han, Zhuoling An   +3 more
doaj   +1 more source