Results 111 to 120 of about 57,485 (298)
, 2018 We hypothesized that dosing vancomycin to achieve trough concentrations of >15 mg/liter overdoses many adults compared to area under the concentration-time curve (AUC)-guided dosing.
Lauren Kato +9 more
core +1 more source
Advanced Science, EarlyView.A healthy gut barrier shields underlying fibroblasts from luminal shear forces, illustrating that “good fences make good neighbors.” Barrier damage exposes fibroblasts to shear stress, inducing cell death and the emergence of stress‐adapted, profibrotic fibroblasts. Sustained shear exposure promotes the formation of stiff aggregates of mechanoadapative
Soyoun Min +6 more
wiley +1 more source
Optimum design of V-trough concentrator for photovoltaic applications
, 2016 This paper presents new simulation of a V-trough concentrator used with photovoltaic module. OptisWorks, an advanced ray tracing software was used to determine the optimum design of the V-trough concentrator.
Al-Shohani, Wisam A.M. +3 more
core +1 more source
Does vancomycin trough concentration useful to predict optimal dosing during continuous venovenous haemofiltration? Preliminary findings from the valley study [PDF]
, 2017 Introduction: Achieving optimal vancomycin dosing, particularly in septic critically ill patients receiving continuous renal replacement therapy (CRRT) is crucial.
Mohd Samat, Noryani +5 more
core +1 more source
Targeting the PDK1/c‐Myc/SOX10 Signaling in Oligodendrocytes Alleviates Neuropathic Pain
Advanced Science, EarlyView.This work reveals that oligodendrocyte homeostasis, mediated by PDK1, is a critical determinant of neuropathic pain (NPP) pathogenesis. Disruption of PDK1 in oligodendrocytes impairs SOX10‐dependent myelination programs through c‐Myc accumulation, leading to disrupted myelination and the pathophysiology of NPP.
Pingping Qiao +7 more
wiley +1 more source
Frontiers in PharmacologyBackgroundThe latest published therapeutic drug monitoring (TDM) guidelines for vancomycin recommend changing trough-based monitoring to area under the concentration-to-time curve (AUC)-based monitoring.
Jieqiong Liu +14 more
doaj +1 more source
RRS Discovery Cruise 312, 11-31 Oct 2006. The extended Ellett Line 2006 [PDF]
, 2007 UK oceanographers have been making repeated measurements on a short section across the Rockall Trough, since 1975. The section consists of a series of stations from the Scottish continental shelf to Rockall.
Allen, J.T.
core
, 2016 International audienceBackground: Tenofovir disoproxil fumarate (TDF)-based regimen is a treatment option for HIV-infected patients. TDF dose adjustment is recommended in patients with impaired renal function.
Tamalet, Catherine +11 more
core +1 more source
Advanced Science, EarlyView.ABSTRACT Inflammatory bowel disease (IBD) is characterized by dysregulated T cell responses. RNA helicases, including DExD‐box helicase 21 (DDX21), are pivotal in RNA metabolism, but their role in T cell‐mediated pathology during IBD remains unclear. Here, we demonstrate that DDX21 expression in CD4+ T cells correlates with cell cycle and translation ...
Yujuan Zhang +11 more
wiley +1 more source
Characteristics of the high-latitude trough
, 1990 The EISCAT radar has provided data for a comprehensive study of the high-latitude trough in electron concentration, which occurs in the auroral zone. In this paper the characteristics of the trough are illustrated, the method of its formation is outlined
Jones, G.O.L. +3 more
core +1 more source