Results 91 to 100 of about 2,565,891 (293)

Enhancing voriconazole therapy in liver dysfunction: exploring administration schemes and predictive factors for trough concentration and efficacy

open access: yesFrontiers in Pharmacology
Introduction: The application of voriconazole in patients with liver dysfunction lacks pharmacokinetic data. In previous study, we proposed to develop voriconazole dosing regimens for these patients according to their total bilirubin, but the regimens ...
Yichang Zhao   +18 more
doaj   +1 more source

Output Characteristics Study of V-trough PV Concentration System

open access: yes, 2011
A V-trough PV system with polysilicon cell array and super cell array has been constructed and tested. Open-circuit voltage, short-circuit current, output power, fill factor and influence of temperature on V-trough PV concentration system have been ...
Cui Qiong Yan
core   +1 more source

Real‐World Longitudinal Data on the Impact of Hydroxychloroquine Blood Level Monitoring on Lupus Outcomes: Results of a Prospective Longitudinal Cohort Study

open access: yesArthritis Care &Research, EarlyView.
Objective Hydroxychloroquine (HCQ) is a cornerstone therapy in systemic lupus erythematosus (SLE), but the weight‐based dosing does not account for clinical factors that can introduce individual variability in drug metabolism and clearance. We leveraged longitudinal data from a prospective SLE cohort to identify clinical factors that predict ...
Jay J. Patel   +6 more
wiley   +1 more source

Is an Apple an Orange? A Large Language Model Benchmark for Candidate Term Extraction and Subclass Decisions Against Upper Ontologies in Engineering and Materials Science

open access: yesAdvanced Engineering Materials, EarlyView.
Building machine‐readable vocabularies for materials science is slow, expert‐driven work. This study benchmarks 13 large language models on two of its first steps: finding candidate terms in engineering articles and deciding where they belong in a class hierarchy.
Thomas Bjarsch   +3 more
wiley   +1 more source

Therapeutic Drug Monitoring and Nephrotoxicity of Teicoplanin Therapy in Chinese Children: A Retrospective Study

open access: yesInfection and Drug Resistance, 2020
Dan Sun,1,* Tao Zhang,1,* Jie Mi,2 Yuzhu Dong,3 Yang Liu,1 Ying Zhang,1 Di Zhang,1 Taotao Wang,1 Hua Cheng,2 Yalin Dong1 1Department of Pharmacy, The First Affiliated Hospital of Xi’an Jiaotong University, Xi’an, Shaanxi 710061, People&rsquo ...
Sun D   +9 more
doaj  

Concentration ratio for a circular trough with flat receiver

open access: yes, 2022
We present a simple analytical formula for the geometric concentration ratio of a circular trough optical concentrator coupled to a flat (planar) receiver.
Timpano, Matteo, Cooper, Thomas A.
core  

PASTA‐ELN: Simplifying Research Data Management for Experimental Materials Science

open access: yesAdvanced Engineering Materials, EarlyView.
Research data management faces ongoing hurdles as many ELNs remain complex and restrictive. PASTA‐ELN offers an open‐source, cross‐platform solution that prioritizes simplicity, offline access, and user control. Its in tuitive folder structure, modular Python add‐ons, and open formats enable seamless documentation, FAIR data practices, and easy ...
S. Brinckmann, G. Winkens, R. Schwaiger
wiley   +1 more source

A retrospective study to estimate serum vancomycin trough concentrations in pediatric patients with current recommended dosing regimen

open access: yesJournal of Medical Sciences, 2018
Background: Vancomycin is widely prescribed to treat infections caused by methicillin-resistant Staphylococcus aureus (MRSA). According to the Infectious Disease Society of America 2011 MRSA guidelines for adults, trough concentrations of 15–20 μg/ml ...
Chia-Ning Chang   +3 more
doaj   +1 more source

Airborne Shape Measurement of Parabolic Trough Collector Fields [PDF]

open access: yes, 2011
As the optical efficiency of the solar field has a high impact on the overall plant performance, qualification methods determining the geometrical accuracy of solar concentrator systems have gained high importance.
Hilgert, Christoph   +4 more
core  

Discrepancies Between Micro Versus Macroscale Viscoelastic Properties in a Microplastic‐Tissue Composite Model

open access: yesAdvanced Engineering Materials, EarlyView.
This study explores the discrepancies between bulk mechanics and spatial mapping in a tissue‐mimetic hydrogel model. Microplastic particles create localized stiff mechanical microenvironments that are detectable by cellular‐scale nanoindentation but leave bulk properties unchanged as measured by rheology.
Ahron T. Verschleisser   +3 more
wiley   +1 more source

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