Results 201 to 210 of about 2,565,891 (293)

Cohort Study to Determine the Impact of CYP3A5 Genotype on Tacrolimus Dosing Requirements and Trough Concentrations in Heart Transplant Recipients [PDF]

Yanting Wu, Michael T. Eadon, Laurie Schenkelberg, Roopa Akkadka Rao, Todd C. Skaar, Emma M. Tillman, Tyler A. Shugg   +6 more
openalex   +1 more source

OsCPK12‐OsATPD1 Module Regulates Photosynthetic Acclimation to Light Stress in Rice

Advanced Science, EarlyView.
OsCPK12 interacts and phosphorylates OsAtpD1 at Ser8 in its transit peptide. This phosphorylation promote its chloroplast translocation, thereby maintaining ATP synthase activity and proton gradient (ΔpH) homeostasis and regulating photosynthetic acclimation, photoprotection, and repair under light stress.
Beifang Wang, Aaron Chan, Yongyi Fan, Yanwu Wang, Pao Xue, Yingxin Zhang, Xiaodeng Zhan, Weixun Wu, Ping Yu, Daibo Chen, Junlin Fu, Yongbo Hong, Xihong Shen, Lianping Sun, Aike Zhu, Shihua Cheng, Qunen Liu, Liyong Cao   +17 more
wiley   +1 more source

Intra-Individual Variability of Vancomycin Trough Concentrations Before and After Implementation of a Standardized Operating Procedure in Orthopedic Inpatients

Moritz Diers, Laura Isabell Werneburg, Alexander Zeh, Natalia Gutteck, Karl-Stefan Delank, Felix Werneburg   +5 more
openalex   +2 more sources

Vancomycin Trough Concentrations and 24-Hour AUC Monitoring in Pediatric Patients

Justin Shiau, Shipra Roy, Paul Sabourenkov, Marc H. Scheetz   +3 more
openalex   +1 more source

Gut Microbiota‐Isoallolithocholic Acid Crosstalk Promotes Calcium Oxalate Kidney Stone Formation via PARP1‐Mediated Parthanatos

Advanced Science, EarlyView.
ABSTRACT Bile acids have been implicated in calcium oxalate (CaOx) nephrolithiasis. Here, we employ multi‐omics approaches to identify isoallolithocholic acid (isoalloLCA) as the key bile acid elevated in the feces, serum, kidney, and urine of CaOx rats, confirmed by spatial metabolomics.
Zijian Zhou, Ruixi Yu, Xuan Zhou, Feng Shi, Zeyu Lin, Peng Gao, Lujia Wang, Ninghan Feng, Zhong Wu, Dawei Wang   +9 more
wiley   +1 more source

Natural‐Inspired Engineered Microalgae With Selenium Enrichment Enabled Potent Anti‐Tumor Immunity

Advanced Science, EarlyView.
Se‐Ssp was engineered as a potent immunomodulator for activating innate immunity via the TLR and cGAS‐STING pathways, therefore converting “cold” tumors into “hot” tumors to achieve high efficacy and long‐term therapeutic outcomes. ABSTRACT Immunotherapy has shed light on clinical oncology for several decades.
Yuqi Yang, Xiaowei Cai, Xiaoyan Zhong, Tian Qiu, Qinwei Lu, Jiahao Qin, Fei Gong, Yecheng Huang, Chenyu Jiang, Youdong Chen, Yuan Cheng, Liang Cheng   +11 more
wiley   +1 more source

Comparison of Trough-Only and Peak–Trough Concentration Data for the Calculation of Vancomycin Area under the Concentration–Time Curve on Day 2 Using Previous and Updated Population Pharmacokinetic Models

Takashi Niwa, Yuto Yamada, Kazuyuki Sumi, Shino Ando, Koshi Sakaida, Rina Takenaka, Akari Nishimura, Mizuki Yamaguchi, Ayasa Goto-Fujibayashi, Koki Hara, Manami Otsubo, Ryohei Miyashita, Akio Suzuki   +12 more
openalex   +1 more source

Development and Validation of a Residual Deep Neural Network for Predicting Vancomycin Trough Concentration Categories in Pediatric Patients [PDF]

Jin Hee Kim, Bongjin Lee, Wonjin Jang, Youngchang Kim, Yonghyuk Jeon, Chunggang Jung, June Dong Park   +6 more
openalex   +1 more source

Mesoporous‐Shell Monolayer Plasmonic Architecture Enables Quantitative and Decision‐Guided SERS

Advanced Science, EarlyView.
Mesoporous‐shell‐regulated molecular transport combined with monolayer hotspot determinism transforms surface‐enhanced Raman spectroscopy (SERS) from ultrasensitive detection into quantitative and decision‐guided molecular sensing. ABSTRACT Quantitative surface‐enhanced Raman spectroscopy (SERS) has long been impeded by stochastic hotspot formation ...
Guangyao Huang, Ying Wang, Yue Fang, Jingyuan Shao, Sensen Hao, Mancun Zhao, Yuan Yao, Junping Wang, Wei Zhou, Hongzhi Wang   +9 more
wiley   +1 more source

Prospective evaluation of imipenem trough concentrations and clinical outcomes in critically ill patients

Mia Madeleine Lidén, Filippo Boroli, Elodie von Dach, Pierre Lescuyer, David Tonoli, Angela Huttner, the OPTIMAL TDM Study Group, Abderrahim Karmime, Rosanne Bourgeois-Pfister, Stephan Harbarth, Benedikt Huttner, Roselyne Ing, Dionysios Neofytos, Virginie Prendki, Xavier Roux   +14 more
openalex   +1 more source