Results 31 to 40 of about 171,760 (178)

A Regression Model to Predict Linezolid Induced Thrombocytopenia in Neonatal Sepsis Patients: A Ten-Year Retrospective Cohort Study

Frontiers in Pharmacology, 2022
Background: Linezolid-induced thrombocytopenia (LIT) is the main factor limiting the clinical application of linezolid (LZD). The incidence and risk factors of LIT in neonatal patients were possibly different from other populations based on ...
Lufen Duan, Qin Zhou, Zongtai Feng, Chenqi Zhu, Yan Cai, Sannan Wang, Meiying Zhu, Jingjing Li, Yunlong Yuan, Xin Liu, Jiantong Sun, Zuming Yang, Lian Tang   +12 more
doaj   +1 more source

Flow of evaporating, gravity-driven thin liquid films over topography [PDF]

, 2006
The effect of topography on the free surface and solvent concentration profiles of an evaporating thin film of liquid flowing down an inclined plane is considered.
H. M. Thompson, M. Sellier, P. H. Gaskell, P. K. Jimack, Trottenberg U.   +4 more
core   +1 more source

Toward Therapeutic Drug Monitoring of Lenalidomide in Hematological Malignancy? Results of an Observational Study of the Exposure-Safety Relationship

Frontiers in Pharmacology, 2022
Objective: Continuous lenalidomide (LEN) therapy is important to achieve a therapeutic effect in patients with multiple myeloma (MM) and non-Hodgkin lymphoma (NHL).
Zaiwei Song, Zaiwei Song, Lan Ma, Li Bao, Yi Ma, Yi Ma, Ping Yang, Ping Yang, Dan Jiang, Dan Jiang, Aijun Liu, Lu Zhang, Yan Li, Yinchu Cheng, Yinchu Cheng, Fei Dong, Rongsheng Zhao, Rongsheng Zhao, Hongmei Jing   +18 more
doaj   +1 more source

Pharmacokinetics and pharmacodynamics of tiotropium solution and tiotropium powder in chronic obstructive pulmonary disease [PDF]

, 2013
The aim of the study was to characterize pharmacokinetics of tiotropium solution 5 µg compared to powder 18 µg and assess dose-dependency of tiotropium solution pharmacodynamics in comparison to placebo.
Cornelissen, PJG, Derom, Eric, Disse, B, Hohlfeld, JM, Peterkin, V, Sharma, A, Towse, L, van Noord, JA   +7 more
core   +1 more source

Mantle melting as a function of water content beneath back-arc basins [PDF]

, 2006
Subduction zone magmas are characterized by high concentrations of H_(2)O, presumably derived from the subducted plate and ultimately responsible for melting at this tectonic setting.
Grove, Timothy L., Hauri, Erik, Kelley, Katherine A., Newman, Sally, Plank, Terry, Stolper, Edward M.   +5 more
core   +1 more source

Design of a Solar Greenhouse with energy Delivery by the Conversion of Near Infrared Radiation. Part 1. Optics and PV-Cells [PDF]

, 2009
In this paper the design and development of a new type of greenhouse with an integrated filter for reflecting near infrared radiation (NIR) and a solar energy delivery system is described.
Bot, G.P.A., Sonneveld, P.J., Swinkels, G.L.A.M.   +2 more
core   +6 more sources

Feasibility of Extrapolating Randomly Taken Plasma Samples to Trough Levels for Therapeutic Drug Monitoring Purposes of Small Molecule Kinase Inhibitors

Pharmaceuticals, 2021
Small molecule kinase inhibitors (SMKIs) are widely used in oncology. Therapeutic drug monitoring (TDM) for SMKIs could reduce underexposure or overexposure.
Ruben A. G. van Eerden, Esther Oomen-de Hoop, Aad Noordam, Ron H. J. Mathijssen, Stijn L. W. Koolen   +4 more
doaj   +1 more source

Isoniazid concentrations in hair and plasma area-under-the-curve exposure among children with tuberculosis. [PDF]

, 2017
We measured hair and plasma concentrations of isoniazid among sixteen children with tuberculosis who underwent personal or video-assisted directly observed therapy and thus had 100% adherence.
Bacchetti, Peter, Bharadwaj, Renu, Dooley, Kelly E., Gandhi, Monica, Gerona, Roy, Gupta, Amita, Gupte, Nikhil, Kagal, Anju, Khwaja, Sultanat, Kinikar, Aarti, Koli, Hari, Kumar, Hemanth, Mave, Vidya, Nimkar, Smita, Ramachandran, Geetha, Wen, Anita, Wilkinson, Katalin Andrea   +16 more
core   +4 more sources

Evaluation of the variability and safety of serum trough concentrations of vancomycin in patients admitted to the intensive care unit

International Journal of Infectious Diseases, 2017
Objective: To examine the variability and safety of serum trough concentrations of vancomycin in patients admitted to the intensive care unit (ICU) and to analyze the factors influencing the trough concentration.
Xiaodan Qian, Guantao Du, Chunmei Weng, Haijun Zhou, Xianju Zhou   +4 more
doaj   +1 more source

A Large Sample Retrospective Study on the Distinction of Voriconazole Concentration in Asian Patients from Different Clinical Departments

Pharmaceuticals, 2021
Voriconazole (VRZ) is widely used to prevent and treat invasive fungal infections; however, there are a few studies examining the variability and influencing the factors of VRZ plasma concentrations across different clinical departments. This study aimed
Yichang Zhao, Chenlin Xiao, Jingjing Hou, Jiamin Wu, Yiwen Xiao, Bikui Zhang, Indy Sandaradura, Miao Yan   +7 more
doaj   +1 more source