Results 131 to 140 of about 163,766 (299)

Tryptophan As a New Member of RNA‐Induced Silencing Complexes Prevents Colon Cancer Liver Metastasis

open access: yesAdvanced Science
Essential amino acids (EAA) and microRNAs (miRs) control biological activity of a cell. Whether EAA regulates the activity of miR has never been demonstrated. Here, as proof‐of‐concept, a tryptophan (Trp, an EAA) complex containing Argonaute 2 (Ago2) and
Fangyi Xu   +11 more
doaj   +1 more source

Trp-Cage Folding on Organic Surfaces

open access: yes, 2015
Trp-cage is an artificial miniprotein that is small, stable, and fast folding due to concerted hydrophobic shielding of a Trp residue by polyproline helices.
Sean A. Fischer (1339596)   +3 more
core   +1 more source

Binding Mode between Trp-Dy(III) Complex and Herring Sperm DNA

open access: yes, 2009
By means of UV and fluorescence spectra, the binding ratios between Dy(III)(Trp)(3) and DNA. in physiological pH environment(pH7.40) were determined as n(Dy(III)(Trp)),:n(DNA) = 2:1 and n(Dy(III)):n(Trp)=1:3.
Xu, Y   +6 more
core  

XPORT-Dependent Transport of TRP and Rhodopsin

open access: yes, 2011
SummaryTRP channels have emerged as key biological sensors in vision, taste, olfaction, hearing, and touch. Despite their importance, virtually nothing is known about the folding and transport of TRP channels during biosynthesis. Here, we identify XPORT (
Vasiljevic, Eva   +11 more
core   +1 more source

Prenatal Poly I:C exposure affects tryptophan-kynurenine metabolism associated with intestinal microbiome in female juvenile rats

open access: yesFrontiers in Immunology
BackgroundEmerging evidence suggests that disrupted tryptophan (TRP) metabolism may contribute to an increased risk of neurodevelopmental disorders (NDDs) in the context of maternal inflammation, with gut microbiota playing a pivotal role in regulating ...
Lirong Yang   +24 more
doaj   +1 more source

TRP channels and pruritus

open access: yes, 2013
Itch (pruritus) is one of the most often seen sensory phenomena in clinical practice. Recent neurophysiological findings proposed the existence of a novel pruriceptive system which includes a multitude of pruritogenic (itch-inducing) peripheral mediators,
Tóth, Balázs István, Bíró, Tamás
core   +1 more source

TRP's: Links to schizophrenia?

open access: yesBiochimica et Biophysica Acta (BBA) - Molecular Basis of Disease, 2007
Schizophrenia is a chronic psychiatric disorder the cause of which is unknown. It is considered to be a neurodevelopmental disorder that results from an interaction of genetic and environmental factors. Direct evidence for links between schizophrenia and TRP channels is lacking. However, several aspects of the pathophysiology of the disorder point to a
openaire   +3 more sources

Sulfoxide-mediated Cys-Trp-selective bioconjugation that enables protein labeling and peptide heterodimerization

open access: yes
A method was developed that enables the magnesium chloride (MgCl2)-activated S-acetamidomethyl cysteine sulfoxide (Cys(Acm)(O)) to induce the sp2(C−H) sulfenylation of the indole ring of Trp residues.
Kota, Hidaka   +15 more
core   +1 more source

Englerin A selectivity against TRP family and non-TRP family ion channels.

open access: yes, 2015
Englerin A selectivity against TRP family and non-TRP family ion channels.
Lei Xu (78676)   +31 more
core   +1 more source

TRP-1 and TPR-2 coordinate SMD neuronal activities with head bending and mediate head muscle contractions.

open access: yes, 2018
(A, C) Representative images showing GCaMP3 fluorescence in the SMD soma of a flp-22p-Δ4::GCaMP3 transgenic worm during dorsal and ventral head bending of the indicated genotypes. The head region (left) and a higher magnification of the boxed area (right)
Jinmahn Kim (787021)   +9 more
core   +1 more source

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