Results 51 to 60 of about 164,112 (301)

TRP channels in thermosensation

Current Opinion in Neurobiology, 2022
The ability to sense external temperature is assumed by somatosensory neurons, in which temperature information is converted to neural activity by afferent input to the central nervous system. Somatosensory neurons consist of various populations with specialized gene expression, including thermosensitive transient receptor potential ion channels ...
Makiko Kashio, Makoto Tominaga
openaire   +2 more sources

TRP channels as biological sensors [PDF]

, 2008
TRP is the most recently discovered family of ion channels and display the largest structure and function diversity among ion channels. Most TRP channels are key elements in sensory cells, where they are involved in the response to a broad range of ...
Astorga, Guadalupe, Bacigalupo, Juan
core  

Geometry and Efficacy of Cross-Strand Trp/Trp, Trp/Tyr, and Tyr/Tyr Aromatic Interaction in a β-Hairpin Peptide [PDF]

, 2016
The Trpzip2 peptide (WTWENGKWTWK-NH2), designed by Cochran and co-workers, contains two pairs of Trp's having cross-strand interaction and forms a stable antiparallel β-hairpin.
Ling Wu (151826), Takahiro Takekiyo (2293357), Dan McElheny (249371), Timothy A. Keiderling (1461238)   +3 more
core   +1 more source

Microfluidic Nano‐Assembly of Red‐Blood‐Cell (RBC) Lipids and Components for Engineering Extracellular Vesicles

Advanced Healthcare Materials, EarlyView.
Engineered red blood cell‐derived extracellular vesicles (eRBCEVs) are synthesized via controlled microfluidic assembly from native RBC lipids, enabling tunable encapsulation of proteins, nucleic acids, nanoparticles, and viral vectors. The platform demonstrates reproducible nanoscale architecture, preserved membrane composition, and functional cargo ...
Chiranth K. Nagaraj, Xilal Y. Rima, Kim T. Nguyen, Courtney Culkins, Nana Boateng, Jacob Doon‐Ralls, Alejandro Bresolin, Xin Huang, Hong Li, Vahedi Amid, Ajeet Pal Singh, Dharti Shantaram, Anastasiia Amari, Mangesh D. Hade, Nicholas R. Merriam, Zachary D. Schultz, Scott Q. Harper, Nizar Y. Saad, Setty M. Magaña, Willa A. Hsueh, Rachel E. Kopec, Blaise R. Kimmel, Andre F. Palmer, Eduardo Reátegui   +23 more
wiley   +1 more source

A self attention based deep learning framework for accurate and efficient dental disease detection in OPG radiographs

Scientific Reports
Oral diseases are increasing now-a-days and there is a high demand for the automatic diagnostic system that helps the clinician to detect these oral diseases with more accuracy and reduced human error.
Ramasubramanian Bhoopalan, S. Mirdula, Priyadharshini Kannusamy, D. Gayathri, D. Manikandan, Krishnaraj Ramaswamy   +5 more
doaj   +1 more source

Glu-Trp-ONa or its acylated analogue (R-Glu-Trp-ONa) administration enhances the wound healing in the model of chronic skin wounds in rabbits [PDF]

, 2015
Maxim A Shevtsov,1,2 Larisa V Smagina,1 Tatiana A Kudriavtceva,3 Sergey V Petlenko,4 Irina V Voronkina1 1Institute of Cytology of the Russian Academy of Sciences (RAS), St Petersburg, Russia; 2IP Pavlov State Medical University of St  ...
Shevtsov MA, Smagina LV, Kudriavtceva TA, Petlenko SV, Voronkina IV   +4 more
core  

Cellular Responses to Mechanical Cues Across Scales: From Fundamental Insights to Translational Potential

Advanced Healthcare Materials, EarlyView.
This review examines how cellular behavior is regulated by mechanical cues transmitted through soft biomaterials, from single‐cell mechanosensing to tissue‐level adaptation. It highlights why physiological relevance, rather than model complexity alone, is critical for translational mechanobiology and introduces a scoring framework linking material ...
Mathias Polz, Manuel P. Kainz, Niklas Haider, Theresa Rienmüller, Kerstin Lenk, Rupert Kargl, Michele Terzano, Gerhard Sommer, Gerhard A. Holzapfel, Julia Fuchs   +9 more
wiley   +1 more source

A successive framework for brain tumor interpretation using Yolo variants

Scientific Reports
Accurate identification and segmentation of brain tumors in Magnetic Resonance Imaging (MRI) images are critical for timely diagnosis and treatment. MRI is frequently used to diagnose these disorders; however medical professionals find it challenging to ...
S. Priyadharshini, Ramasubramanian Bhoopalan, D. Manikandan, Krishnaraj Ramaswamy   +3 more
doaj   +1 more source

Transient receptor potential (TRP) channels: a metabolic TR(i)P to obesity prevention and therapy [PDF]

, 2018
Cellular transport of ions, especially by ion channels, regulates physiological function. The transient receptor potential (TRP) channels, with 30 identified so far, are cation channels with high calcium permeability.
Bishnoi, M., Panchal, SK, Khare, P., Panchal, Sunil K. (R20071), Khare, Pragyanshu, L. Brown, Panchal, S. K., Brown, Lindsay, M. Bishnoi, P. Khare, Bishnoi, M, S. K. Panchal, Brown, L., Khare, P, Bishnoi, Mahendra, Brown, L   +15 more
core   +1 more source

Temporal Immune and Metabolic Shifts Drive the Anti‐Tumor Efficacy of Resiquimod‐Loaded Nanoparticles in Peritoneal Carcinomatosis

Advanced Healthcare Materials, EarlyView.
Peritoneal carcinomatosis is a hard‐to‐treat spread of abdominal cancers that often returns after therapy. Nanoparticles were developed to retain an immune‐boosting drug in the abdomen. When combined with chemotherapy in mice, this approach eliminated tumors in many cases and prevented recurrence, helping the immune system mount a stronger, longer ...
Vanessa Chan, Po‐Han Chao, XuXin Sun, Jun Han, Sarah MacPherson, Lucas J. Andrew, Noah Y. Brittain, Tien Do, Marcel B. Bally, Julian J. Lum, Shyh‐Dar Li   +10 more
wiley   +1 more source