Results 31 to 40 of about 163,766 (299)

Pan-cancer analyses reveal the genetic and pharmacogenomic landscape of transient receptor potential channels

npj Genomic Medicine, 2022
Transient-receptor potential (TRP) channels comprise a diverse family of ion channels, which play important roles in regulation of intracellular calcium.
Tao Pan, Yueying Gao, Gang Xu, Ping Zhou, Si Li, Jing Guo, Haozhe Zou, Qi Xu, Xiaoyan Huang, Juan Xu, Yongsheng Li   +10 more
doaj   +1 more source

Pan-Cancer Analysis of the TRP Family, Especially TRPV4 and TRPC4, and Its Expression Correlated with Prognosis, Tumor Microenvironment, and Treatment Sensitivity

Biomolecules, 2023
Background: Transient receptor potential (TRP) channels are involved in various physiological, pathological, and tumorigenesis-related processes. However, only a few studies have comprehensively analyzed TRP family members and their association with ...
Zhenghao Chen, Youquan Zhao, Ye Tian, Rui Cao, Donghao Shang   +4 more
doaj   +1 more source

Trp

, 2022
Decoding Trp regulatory ...
Guoji Guo (1374606)
core   +1 more source

Establishing an assay to evaluate d‐amino acid oxidase enzyme kinetics and inhibition using WST‐8 redox dye

FEBS Open Bio, EarlyView.
This study investigated a novel WST‐8‐based assay for evaluating d‐Amino acid oxidase (DAO) inhibitors. We confirmed its effectiveness using known inhibitors and found that uremic toxins possess relatively weak inhibitory activity compared to existing drugs.
Kahoko Miyake, Yuki Enoki, Yuka Nakazawa, Kazuaki Taguchi, Kazuaki Matsumoto   +4 more
wiley   +1 more source

Trp [PDF]

, 2019
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openaire   +3 more sources

A novel approach for the segmentation of retinal images by integration K-means clustering algorithm with graph cut for image segmentation

Scientific Reports
Diabetic retinopathy (DR) is a foremost cause of vision impairment, characterized by the presence of microaneurysms, exudates, and other intricate retinal lesions.
Ramasubramanian Bhoopalan, S. Priyadharshini   +1 more
doaj   +1 more source

AAV9-Mediated Overexpression of TRPM4 Increases the Incidence of Stress-Induced Ventricular Arrhythmias in Mice

Frontiers in Physiology, 2019
Ca2+ activated non-selective (CAN) cation channels have been described in cardiomyocytes since the advent of the patch clamp technique. It has been hypothesized that this type of ion channel contributes to the triggering of cardiac arrhythmias.
Andy Pironet, Ninda Syam, Frone Vandewiele, Chris Van den Haute, Sara Kerselaers, Silvia Pinto, Greetje Vande Velde, Rik Gijsbers, Rudi Vennekens   +8 more
doaj   +1 more source

TRP channels at a glance [PDF]

Journal of Cell Science, 2004
The t ransient r eceptor p otential (TRP) superfamily consists of a diverse set of proteins whose primary function is to regulate the plasma membrane permeability of animal cells to a variety of ions.
Raghu, Padinjat, Simon, Andrews
openaire   +2 more sources

Emergence of functional sensory subtypes as defined by transient receptor potential channel expression

, 2007
The existence of heterogeneous populations of dorsal root ganglion (DRG) neurons conveying different somatosensory information is the basis for the perception of touch, temperature, and pain. A differential expression of transient receptor potential (TRP)
Hjerling-Leffler, J, Ernfors, P, Ernfors, P,, Koltzenburg, M, AlQatari, M   +4 more
core   +1 more source

Decreased cold‐sensing function of the transient receptor potential channel TRPM8 from tailed amphibians

FEBS Open Bio, EarlyView.
Despite frogs avoiding low temperatures, examination of four salamander species revealed that none avoided cold and all possessed cold tolerance. Functional analysis of TRPM8, a cold sensor, showed that all salamander TRPM8s had lost their cold sensitivity.
Tadahiro Sawao, Daiki Kobayashi, Shogo Hori, Osamu Saitoh   +3 more
wiley   +1 more source