Results 41 to 50 of about 164,112 (301)

A novel approach for the segmentation of retinal images by integration K-means clustering algorithm with graph cut for image segmentation

Scientific Reports
Diabetic retinopathy (DR) is a foremost cause of vision impairment, characterized by the presence of microaneurysms, exudates, and other intricate retinal lesions.
Ramasubramanian Bhoopalan, S. Priyadharshini   +1 more
doaj   +1 more source

AAV9-Mediated Overexpression of TRPM4 Increases the Incidence of Stress-Induced Ventricular Arrhythmias in Mice

Frontiers in Physiology, 2019
Ca2+ activated non-selective (CAN) cation channels have been described in cardiomyocytes since the advent of the patch clamp technique. It has been hypothesized that this type of ion channel contributes to the triggering of cardiac arrhythmias.
Andy Pironet, Ninda Syam, Frone Vandewiele, Chris Van den Haute, Sara Kerselaers, Silvia Pinto, Greetje Vande Velde, Rik Gijsbers, Rudi Vennekens   +8 more
doaj   +1 more source

TRP channels at a glance [PDF]

Journal of Cell Science, 2004
The t ransient r eceptor p otential (TRP) superfamily consists of a diverse set of proteins whose primary function is to regulate the plasma membrane permeability of animal cells to a variety of ions.
Raghu, Padinjat, Simon, Andrews
openaire   +2 more sources

Hőérzékeny tranziens receptor potenciál (TRP) ioncsatornák vizsgálata humán dermális fibroblasztokon [PDF]

, 2017
Diplomadolgozatom témája a hőérzékeny tranziens receptor potenciál (TRP) ioncsatornák vizsgálata humán dermális fibroblasztokon. Megállapítottuk, hogy a TRPM3 ioncsatorna nem expresszálódik HDF sejteken.
Radnóti, Enikő
core  

Decreased cold‐sensing function of the transient receptor potential channel TRPM8 from tailed amphibians

FEBS Open Bio, EarlyView.
Despite frogs avoiding low temperatures, examination of four salamander species revealed that none avoided cold and all possessed cold tolerance. Functional analysis of TRPM8, a cold sensor, showed that all salamander TRPM8s had lost their cold sensitivity.
Tadahiro Sawao, Daiki Kobayashi, Shogo Hori, Osamu Saitoh   +3 more
wiley   +1 more source

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

FEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin, Naghme Radmannia, David N. Huynh, Liliane Ménard, Caroline Daneault, Maïté Veilleux, Ahsanullah Ahsanullah, André C. Carpentier, William D. Lubell, Matthieu Ruiz, Huy Ong, Sylvie Marleau, Simon‐Pierre Gravel   +12 more
wiley   +1 more source

Gut Microbiota Metabolite Indole Propionic Acid Targets Tryptophan Biosynthesis in Mycobacterium tuberculosis

mBio, 2019
Indole propionic acid (IPA), produced by the gut microbiota, is active against Mycobacterium tuberculosis in vitro and in vivo. However, its mechanism of action is unknown.
Dereje Abate Negatu, Yoshiyuki Yamada, Yu Xi, Mei Lin Go, Matthew Zimmerman, Uday Ganapathy, Véronique Dartois, Martin Gengenbacher, Thomas Dick   +8 more
doaj   +1 more source

Organellar TRP channels [PDF]

Nature Structural & Molecular Biology, 2018
Mammalian transient receptor potential (TRP) channels mediate Ca2+ flux and voltage changes across membranes in response to environmental and cellular signals. At the plasma membrane, sensory TRPs act as neuronal detectors of physical and chemical environmental signals, and receptor-operated (metabotropic) TRPs decode extracellular neuroendocrine cues ...
Xiaoli Zhang, Meiqin Hu, Yexin Yang, Haoxing Xu   +3 more
openaire   +2 more sources

Bismuth‐Based Photocatalysts for Water Remediation: Design Strategies, Mechanisms, and Challenges

Advanced Functional Materials, EarlyView.
This review highlights representative design strategies for bismuth‐based semiconductor photocatalysts in solar‐driven water purification. Emphasis is placed on electronic structure regulation, oxygen‐vacancy engineering, and interfacial coupling to enable efficient full‐spectrum light utilization, improved charge separation, and selective oxidation in
Shan Liu, Yi Zhao, Liming Cai, Simin Long, Jing Kang, Jingkai Lin, Jimin Shen, Zhonglin Chen, Shaobin Wang, Huayang Zhang   +9 more
wiley   +1 more source

High-precision non-destructive blade surface inspection via self learning transformer networks

Scientific Reports
Accurate identification of defects in Jet Engine Turbine and compressor blade surface plays a vital role in ensuring engine efficiency, safety and secure life.
Priyadharshini Kannusamy, D. Gayathri, S. Mirdula, Ramasubramanian Bhoopalan, D. Manikandan, Krishnaraj Ramaswamy   +5 more
doaj   +1 more source